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yes, it's me... the "who the fuck is eichi" guy

@rythyme / rythyme.tumblr.com

Theo | 29 | Seattle | they/them | queer | Join me for memes and gay shit! Currently reblogging mostly BL dramas with a few other fruity things mixed in. Find my fic on AO3 under pugglemuggle.
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Reblogged witchaj

When Drugs Became Available

Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:

  • Acetaminophen: 1950
  • Albuterol: 1969 (UK) 1982 (US)
  • Allopurinol: 1966
  • Alprazolam: 1981
  • Amitriptyline: 1961
  • Amlodipine: 1990
  • Amoxicilin: 1972
  • Amphetamine/Dextroamphetamine (together as Adderall): 1996
  • Apixiban: 2012
  • Aripiprazole: 2002
  • Aspirin (first NSAID): 1899
  • Azidothymidine (first antiviral): 1987
  • Barbital (first barbiturate): 1903
  • Bupropion: 1985
  • Buspirone: 1986
  • Calcium Carbonate (TUMS): 1930
  • Captopril (first ACE inhibitor): 1981
  • Chlordiazepoxide (first benzodiazepine): 1960
  • Chlorothiazide (first thiazide diuretic): 1957
  • Chlorpromazine (first antipsychotic): 1952
  • Cyclobenzeprine: 1977
  • Diphenhydramine: 1946
  • Furosemide: 1959
  • Fluoxetine (first SSRI): 1988
  • Gabapentin: 1993
  • Glipizide: 1984
  • Hydrochlorothiazide: 1959
  • Ibuprofen: 1969 (UK) 1974 (US)
  • Insulin: 1923 (though many types of insulins would become available over the next century)
  • Imipramine (first tricyclic antidepressant): 1959
  • Iproniazid (first antidepressant (MAOI)): 1952
  • Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
  • Lisinopril: 1987
  • Lithium: 1949
  • Losartan (first ARB): 1995
  • Lovastatin (first statin): 1987
  • Naproxen: 1976 (Rx) 1990 (OTC)
  • Nitrogen Mustard (first chemotherapy agent): early 1940's
  • Methotrexate: 1947
  • Methylphenidate: 1954
  • Metformin: 1957 (France) 1995 (US)
  • Metoprolol: 1978
  • Montelukast: 1998
  • Morphine: early 1800's
  • Omeprazole: 1989
  • Penicillin: 1945
  • Phenbezamine (first antihistamine): 1942
  • Prednisone: 1955
  • Propranolol (first beta blocker): 1965 (UK) 1967 (US)
  • Sertraline: 1990
  • Spironolactone: 1959
  • Sulfanilamide (first modern antibiotic): 1935
  • Tolbutamide (first oral anti-diabetic drug): 1956
  • Tramadol: 1977 (Germany) 1995 (US)
  • Trazodone: 1981
  • Valacyclovir: 1995
  • Verapamil (first calcium channel blocker): 1964
  • Warfarin: 1954
  • Zopiclone (first "Z-drug"): 1986

Someone asked for this list in date order, so here it is!

  • Morphine: early 1800's
  • Aspirin (first NSAID): 1899
  • Barbital (first barbiturate): 1903
  • Insulin: 1923 (though many types of insulins would become available over the next century)
  • Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
  • Calcium Carbonate (TUMS): 1930
  • Sulfanilamide (first modern antibiotic): 1935
  • Nitrogen Mustard (first chemotherapy agent): early 1940's
  • Phenbezamine (first antihistamine): 1942
  • Penicillin: 1945
  • Diphenhydramine: 1946
  • Methotrexate: 1947
  • Lithium: 1949
  • Acetaminophen: 1950
  • Chlorpromazine (first antipsychotic): 1952
  • Iproniazid (first antidepressant (MAOI)): 1952
  • Methylphenidate: 1954
  • Warfarin: 1954
  • Prednisone: 1955
  • Tolbutamide (first oral anti-diabetic drug): 1956
  • Chlorothiazide (first thiazide diuretic): 1957
  • Metformin: 1957 (France) 1995 (US)
  • Furosemide: 1959
  • Hydrochlorothiazide: 1959
  • Spironolactone: 1959
  • Imipramine (first tricyclic antidepressant): 1959
  • Chlordiazepoxide (first benzodiazepine): 1960
  • Amitriptyline: 1961
  • Verapamil (first calcium channel blocker): 1964
  • Propranolol (first beta blocker): 1965 (UK) 1967 (US)
  • Allopurinol: 1966
  • Albuterol: 1969 (UK) 1982 (US)
  • Ibuprofen: 1969 (UK) 1974 (US)
  • Amoxicilin: 1972
  • Naproxen: 1976 (Rx) 1990 (OTC)
  • Cyclobenzeprine: 1977
  • Tramadol: 1977 (Germany) 1995 (US)
  • Metoprolol: 1978
  • Captopril (first ACE inhibitor): 1981
  • Trazodone: 1981
  • Alprazolam: 1981
  • Glipizide: 1984
  • Bupropion: 1985
  • Buspirone: 1986
  • Zopiclone (first "Z-drug"): 1986
  • Lovastatin (first statin): 1987
  • Azidothymidine (first antiviral): 1987
  • Lisinopril: 1987
  • Fluoxetine (first SSRI): 1988
  • Omeprazole: 1989
  • Amlodipine: 1990
  • Sertraline: 1990
  • Gabapentin: 1993
  • Losartan (first ARB): 1995
  • Valacyclovir: 1995
  • Amphetamine/Dextroamphetamine (together as Adderall): 1996
  • Montelukast: 1998
  • Aripiprazole: 2002
  • Apixiban: 2012
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Reblogged boatkong

having a headache while hydrated is so unfair. you were supposed to protect me.

“my father is a boy and my mother is a girl so i’m mixed” is the funniest possible response to someone asking your gender and it came from 6’5 Viking footballer and notable weird little guy Erling Haaland on a Snapchat

comedians can only dream of writing something this funny

we all love dynamics that remind us of the moon and the sun but I am baffled by the lack of love for dynamics that are reminiscent of the moon and the EARTH.

I am so full of life but you are the reason my tides have a rhythm. you are the reason my oceans are brimming with life. you are the reason I can see the light in myself even when it all seems dark and you are the reason my orbit is stable and my seasons make sense. do you see it

Moon has scars from meteors that would’ve otherwise hit us

AOAOIUUHHH. NOBODY TALK TO ME