the problem is i really do love staying up until one billion o'clock. it just cant be helped
Inconvenient Exit , Detail - Simon Bang , 2026.
Danish , b. 1960 -
Acrylic on canvas , 54 x 95 cm.
Naches Peak and Dewey Lake, July 29th, Mount Rainier/Tahoma National Park
When Drugs Became Available
Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:
- Acetaminophen: 1950
- Albuterol: 1969 (UK) 1982 (US)
- Allopurinol: 1966
- Alprazolam: 1981
- Amitriptyline: 1961
- Amlodipine: 1990
- Amoxicilin: 1972
- Amphetamine/Dextroamphetamine (together as Adderall): 1996
- Apixiban: 2012
- Aripiprazole: 2002
- Aspirin (first NSAID): 1899
- Azidothymidine (first antiviral): 1987
- Barbital (first barbiturate): 1903
- Bupropion: 1985
- Buspirone: 1986
- Calcium Carbonate (TUMS): 1930
- Captopril (first ACE inhibitor): 1981
- Chlordiazepoxide (first benzodiazepine): 1960
- Chlorothiazide (first thiazide diuretic): 1957
- Chlorpromazine (first antipsychotic): 1952
- Cyclobenzeprine: 1977
- Diphenhydramine: 1946
- Furosemide: 1959
- Fluoxetine (first SSRI): 1988
- Gabapentin: 1993
- Glipizide: 1984
- Hydrochlorothiazide: 1959
- Ibuprofen: 1969 (UK) 1974 (US)
- Insulin: 1923 (though many types of insulins would become available over the next century)
- Imipramine (first tricyclic antidepressant): 1959
- Iproniazid (first antidepressant (MAOI)): 1952
- Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
- Lisinopril: 1987
- Lithium: 1949
- Losartan (first ARB): 1995
- Lovastatin (first statin): 1987
- Naproxen: 1976 (Rx) 1990 (OTC)
- Nitrogen Mustard (first chemotherapy agent): early 1940's
- Methotrexate: 1947
- Methylphenidate: 1954
- Metformin: 1957 (France) 1995 (US)
- Metoprolol: 1978
- Montelukast: 1998
- Morphine: early 1800's
- Omeprazole: 1989
- Penicillin: 1945
- Phenbezamine (first antihistamine): 1942
- Prednisone: 1955
- Propranolol (first beta blocker): 1965 (UK) 1967 (US)
- Sertraline: 1990
- Spironolactone: 1959
- Sulfanilamide (first modern antibiotic): 1935
- Tolbutamide (first oral anti-diabetic drug): 1956
- Tramadol: 1977 (Germany) 1995 (US)
- Trazodone: 1981
- Valacyclovir: 1995
- Verapamil (first calcium channel blocker): 1964
- Warfarin: 1954
- Zopiclone (first "Z-drug"): 1986
Someone asked for this list in date order, so here it is!
- Morphine: early 1800's
- Aspirin (first NSAID): 1899
- Barbital (first barbiturate): 1903
- Insulin: 1923 (though many types of insulins would become available over the next century)
- Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
- Calcium Carbonate (TUMS): 1930
- Sulfanilamide (first modern antibiotic): 1935
- Nitrogen Mustard (first chemotherapy agent): early 1940's
- Phenbezamine (first antihistamine): 1942
- Penicillin: 1945
- Diphenhydramine: 1946
- Methotrexate: 1947
- Lithium: 1949
- Acetaminophen: 1950
- Chlorpromazine (first antipsychotic): 1952
- Iproniazid (first antidepressant (MAOI)): 1952
- Methylphenidate: 1954
- Warfarin: 1954
- Prednisone: 1955
- Tolbutamide (first oral anti-diabetic drug): 1956
- Chlorothiazide (first thiazide diuretic): 1957
- Metformin: 1957 (France) 1995 (US)
- Furosemide: 1959
- Hydrochlorothiazide: 1959
- Spironolactone: 1959
- Imipramine (first tricyclic antidepressant): 1959
- Chlordiazepoxide (first benzodiazepine): 1960
- Amitriptyline: 1961
- Verapamil (first calcium channel blocker): 1964
- Propranolol (first beta blocker): 1965 (UK) 1967 (US)
- Allopurinol: 1966
- Albuterol: 1969 (UK) 1982 (US)
- Ibuprofen: 1969 (UK) 1974 (US)
- Amoxicilin: 1972
- Naproxen: 1976 (Rx) 1990 (OTC)
- Cyclobenzeprine: 1977
- Tramadol: 1977 (Germany) 1995 (US)
- Metoprolol: 1978
- Captopril (first ACE inhibitor): 1981
- Trazodone: 1981
- Alprazolam: 1981
- Glipizide: 1984
- Bupropion: 1985
- Buspirone: 1986
- Zopiclone (first "Z-drug"): 1986
- Lovastatin (first statin): 1987
- Azidothymidine (first antiviral): 1987
- Lisinopril: 1987
- Fluoxetine (first SSRI): 1988
- Omeprazole: 1989
- Amlodipine: 1990
- Sertraline: 1990
- Gabapentin: 1993
- Losartan (first ARB): 1995
- Valacyclovir: 1995
- Amphetamine/Dextroamphetamine (together as Adderall): 1996
- Montelukast: 1998
- Aripiprazole: 2002
- Apixiban: 2012
wedding dresses are white specifically so that if the bride goes axe-crazy you can rest assured you will see the blood stains all over her and it'll be sick as fuck
we all love dynamics that remind us of the moon and the sun but I am baffled by the lack of love for dynamics that are reminiscent of the moon and the EARTH.
I am so full of life but you are the reason my tides have a rhythm. you are the reason my oceans are brimming with life. you are the reason I can see the light in myself even when it all seems dark and you are the reason my orbit is stable and my seasons make sense. do you see it
Moon has scars from meteors that would’ve otherwise hit us
AOAOIUUHHH. NOBODY TALK TO ME
What to Read After Watching The Odyssey 🏺
Top BL Series: Director Edition
Starting a new poll series. Gonna start with one of the most well-known.






