the problem is i really do love staying up until one billion o'clock. it just cant be helped
When Drugs Became Available
Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:
- Acetaminophen: 1950
- Albuterol: 1969 (UK) 1982 (US)
- Allopurinol: 1966
- Alprazolam: 1981
- Amitriptyline: 1961
- Amlodipine: 1990
- Amoxicilin: 1972
- Amphetamine/Dextroamphetamine (together as Adderall): 1996
- Apixiban: 2012
- Aripiprazole: 2002
- Aspirin (first NSAID): 1899
- Azidothymidine (first antiviral): 1987
- Barbital (first barbiturate): 1903
- Bupropion: 1985
- Buspirone: 1986
- Calcium Carbonate (TUMS): 1930
- Captopril (first ACE inhibitor): 1981
- Chlordiazepoxide (first benzodiazepine): 1960
- Chlorothiazide (first thiazide diuretic): 1957
- Chlorpromazine (first antipsychotic): 1952
- Cyclobenzeprine: 1977
- Diphenhydramine: 1946
- Furosemide: 1959
- Fluoxetine (first SSRI): 1988
- Gabapentin: 1993
- Glipizide: 1984
- Hydrochlorothiazide: 1959
- Ibuprofen: 1969 (UK) 1974 (US)
- Insulin: 1923 (though many types of insulins would become available over the next century)
- Imipramine (first tricyclic antidepressant): 1959
- Iproniazid (first antidepressant (MAOI)): 1952
- Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
- Lisinopril: 1987
- Lithium: 1949
- Losartan (first ARB): 1995
- Lovastatin (first statin): 1987
- Naproxen: 1976 (Rx) 1990 (OTC)
- Nitrogen Mustard (first chemotherapy agent): early 1940's
- Methotrexate: 1947
- Methylphenidate: 1954
- Metformin: 1957 (France) 1995 (US)
- Metoprolol: 1978
- Montelukast: 1998
- Morphine: early 1800's
- Omeprazole: 1989
- Penicillin: 1945
- Phenbezamine (first antihistamine): 1942
- Prednisone: 1955
- Propranolol (first beta blocker): 1965 (UK) 1967 (US)
- Sertraline: 1990
- Spironolactone: 1959
- Sulfanilamide (first modern antibiotic): 1935
- Tolbutamide (first oral anti-diabetic drug): 1956
- Tramadol: 1977 (Germany) 1995 (US)
- Trazodone: 1981
- Valacyclovir: 1995
- Verapamil (first calcium channel blocker): 1964
- Warfarin: 1954
- Zopiclone (first "Z-drug"): 1986
Someone asked for this list in date order, so here it is!
- Morphine: early 1800's
- Aspirin (first NSAID): 1899
- Barbital (first barbiturate): 1903
- Insulin: 1923 (though many types of insulins would become available over the next century)
- Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
- Calcium Carbonate (TUMS): 1930
- Sulfanilamide (first modern antibiotic): 1935
- Nitrogen Mustard (first chemotherapy agent): early 1940's
- Phenbezamine (first antihistamine): 1942
- Penicillin: 1945
- Diphenhydramine: 1946
- Methotrexate: 1947
- Lithium: 1949
- Acetaminophen: 1950
- Chlorpromazine (first antipsychotic): 1952
- Iproniazid (first antidepressant (MAOI)): 1952
- Methylphenidate: 1954
- Warfarin: 1954
- Prednisone: 1955
- Tolbutamide (first oral anti-diabetic drug): 1956
- Chlorothiazide (first thiazide diuretic): 1957
- Metformin: 1957 (France) 1995 (US)
- Furosemide: 1959
- Hydrochlorothiazide: 1959
- Spironolactone: 1959
- Imipramine (first tricyclic antidepressant): 1959
- Chlordiazepoxide (first benzodiazepine): 1960
- Amitriptyline: 1961
- Verapamil (first calcium channel blocker): 1964
- Propranolol (first beta blocker): 1965 (UK) 1967 (US)
- Allopurinol: 1966
- Albuterol: 1969 (UK) 1982 (US)
- Ibuprofen: 1969 (UK) 1974 (US)
- Amoxicilin: 1972
- Naproxen: 1976 (Rx) 1990 (OTC)
- Cyclobenzeprine: 1977
- Tramadol: 1977 (Germany) 1995 (US)
- Metoprolol: 1978
- Captopril (first ACE inhibitor): 1981
- Trazodone: 1981
- Alprazolam: 1981
- Glipizide: 1984
- Bupropion: 1985
- Buspirone: 1986
- Zopiclone (first "Z-drug"): 1986
- Lovastatin (first statin): 1987
- Azidothymidine (first antiviral): 1987
- Lisinopril: 1987
- Fluoxetine (first SSRI): 1988
- Omeprazole: 1989
- Amlodipine: 1990
- Sertraline: 1990
- Gabapentin: 1993
- Losartan (first ARB): 1995
- Valacyclovir: 1995
- Amphetamine/Dextroamphetamine (together as Adderall): 1996
- Montelukast: 1998
- Aripiprazole: 2002
- Apixiban: 2012












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