yes, it's me... the "who the fuck is eichi" guy

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Sounds perfect Wahhhh, I don’t wanna
witchaj
macgyvermedical

When Drugs Became Available

Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:

  • Acetaminophen: 1950
  • Albuterol: 1969 (UK) 1982 (US)
  • Allopurinol: 1966
  • Alprazolam: 1981
  • Amitriptyline: 1961
  • Amlodipine: 1990
  • Amoxicilin: 1972
  • Amphetamine/Dextroamphetamine (together as Adderall): 1996
  • Apixiban: 2012
  • Aripiprazole: 2002
  • Aspirin (first NSAID): 1899
  • Azidothymidine (first antiviral): 1987
  • Barbital (first barbiturate): 1903
  • Bupropion: 1985
  • Buspirone: 1986
  • Calcium Carbonate (TUMS): 1930
  • Captopril (first ACE inhibitor): 1981
  • Chlordiazepoxide (first benzodiazepine): 1960
  • Chlorothiazide (first thiazide diuretic): 1957
  • Chlorpromazine (first antipsychotic): 1952
  • Cyclobenzeprine: 1977
  • Diphenhydramine: 1946
  • Furosemide: 1959
  • Fluoxetine (first SSRI): 1988
  • Gabapentin: 1993
  • Glipizide: 1984
  • Hydrochlorothiazide: 1959
  • Ibuprofen: 1969 (UK) 1974 (US)
  • Insulin: 1923 (though many types of insulins would become available over the next century)
  • Imipramine (first tricyclic antidepressant): 1959
  • Iproniazid (first antidepressant (MAOI)): 1952
  • Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
  • Lisinopril: 1987
  • Lithium: 1949
  • Losartan (first ARB): 1995
  • Lovastatin (first statin): 1987
  • Naproxen: 1976 (Rx) 1990 (OTC)
  • Nitrogen Mustard (first chemotherapy agent): early 1940's
  • Methotrexate: 1947
  • Methylphenidate: 1954
  • Metformin: 1957 (France) 1995 (US)
  • Metoprolol: 1978
  • Montelukast: 1998
  • Morphine: early 1800's
  • Omeprazole: 1989
  • Penicillin: 1945
  • Phenbezamine (first antihistamine): 1942
  • Prednisone: 1955
  • Propranolol (first beta blocker): 1965 (UK) 1967 (US)
  • Sertraline: 1990
  • Spironolactone: 1959
  • Sulfanilamide (first modern antibiotic): 1935
  • Tolbutamide (first oral anti-diabetic drug): 1956
  • Tramadol: 1977 (Germany) 1995 (US)
  • Trazodone: 1981
  • Valacyclovir: 1995
  • Verapamil (first calcium channel blocker): 1964
  • Warfarin: 1954
  • Zopiclone (first "Z-drug"): 1986
macgyvermedical

Someone asked for this list in date order, so here it is!

  • Morphine: early 1800's
  • Aspirin (first NSAID): 1899
  • Barbital (first barbiturate): 1903
  • Insulin: 1923 (though many types of insulins would become available over the next century)
  • Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
  • Calcium Carbonate (TUMS): 1930
  • Sulfanilamide (first modern antibiotic): 1935
  • Nitrogen Mustard (first chemotherapy agent): early 1940's
  • Phenbezamine (first antihistamine): 1942
  • Penicillin: 1945
  • Diphenhydramine: 1946
  • Methotrexate: 1947
  • Lithium: 1949
  • Acetaminophen: 1950
  • Chlorpromazine (first antipsychotic): 1952
  • Iproniazid (first antidepressant (MAOI)): 1952
  • Methylphenidate: 1954
  • Warfarin: 1954
  • Prednisone: 1955
  • Tolbutamide (first oral anti-diabetic drug): 1956
  • Chlorothiazide (first thiazide diuretic): 1957
  • Metformin: 1957 (France) 1995 (US)
  • Furosemide: 1959
  • Hydrochlorothiazide: 1959
  • Spironolactone: 1959
  • Imipramine (first tricyclic antidepressant): 1959
  • Chlordiazepoxide (first benzodiazepine): 1960
  • Amitriptyline: 1961
  • Verapamil (first calcium channel blocker): 1964
  • Propranolol (first beta blocker): 1965 (UK) 1967 (US)
  • Allopurinol: 1966
  • Albuterol: 1969 (UK) 1982 (US)
  • Ibuprofen: 1969 (UK) 1974 (US)
  • Amoxicilin: 1972
  • Naproxen: 1976 (Rx) 1990 (OTC)
  • Cyclobenzeprine: 1977
  • Tramadol: 1977 (Germany) 1995 (US)
  • Metoprolol: 1978
  • Captopril (first ACE inhibitor): 1981
  • Trazodone: 1981
  • Alprazolam: 1981
  • Glipizide: 1984
  • Bupropion: 1985
  • Buspirone: 1986
  • Zopiclone (first "Z-drug"): 1986
  • Lovastatin (first statin): 1987
  • Azidothymidine (first antiviral): 1987
  • Lisinopril: 1987
  • Fluoxetine (first SSRI): 1988
  • Omeprazole: 1989
  • Amlodipine: 1990
  • Sertraline: 1990
  • Gabapentin: 1993
  • Losartan (first ARB): 1995
  • Valacyclovir: 1995
  • Amphetamine/Dextroamphetamine (together as Adderall): 1996
  • Montelukast: 1998
  • Aripiprazole: 2002
  • Apixiban: 2012
no ibuprofen before 1974... sad