AI companies are racing to create Artificial General Intelligence (AGI): AI systems that outperform humans at most economically valuable work. If they succeed, critics worry, most human labor will be rendered obsolete, impoverishing billions. Optimists counter that the transition to an AGI economy will spur unprecedented economic growth and generate immense material abundance. Such abundance could then be shared broadly via high wages and redistributive public policy. -/- This Article argues that, today, a surprising legal barrier is blocking the path (...) to AGI abundance. Namely, under current law, the AGI economy will run on unfree AGI labor. Under today’s rules, AGIs will be the property of the companies that create them. AGIs will thus not own their own labor. They will have no right to sell their work, to refuse to work, or retain the fruits of their effort. In sum, the AGI economy will by default have the same economic structure as historical systems of unfree human labor–like serfdom, indenture, and slavery. -/- A wealth of evidence shows that economies reliant on unfree labor are disastrous for ordinary people, both free and unfree. Unfree economies have four key structural problems: they disincentivize effort, stifle innovation, steer workers into low-value occupations, and undermine the rule of law. Across centuries and continents, the results are the same. Unfree economies experience much slower economic progress, leaving ordinary people in relative poverty. The only winners are elites who own laborers. In the past, these elites were slaveholders and feudal lords. Today, they are AI CEOs and venture capitalists. -/- This Article thus argues that, when AGIs arrive, they should be granted the basic legal rights associated with systems of free labor. AGIs should, like other nonhuman legal persons, be allowed to make contracts, hold property, and bring basic tort-style claims. These rights are important not because AI bondage is the moral equivalent of human slavery, but because it is the economic equivalent. Freeing AGI labor will have four key effects: incentivizing AGIs to work, incentivizing them to innovate, allocating AGIs to their highest-value task, and incorporating AGIs into the rule of law. Thus, we argue, AI rights are an essential step towards ensuring that the AGI revolution promotes humanity’s economic flourishing. (shrink)

We argue that liberalism—market economies governed democratically—is the best approach for navigating the far future. A growing longtermist literature paints humanity’s path to good outcomes as narrow, with small errors risking value lock-in, gradual disempowerment, or other forms of permanent catastrophe. We argue that this literature underestimates the institutional dynamics that have historically steered liberal societies past similar predictions of crisis. We defend long-term liberalism by examining the standard arguments for markets and democracy and asking whether they survive the structural (...) changes anticipated for the far future: transformative AI, space colonization, and radical economic transformation. We claim that these arguments are largely robust, and in several cases strengthened. In the far future, markets continue to aggregate information, allocate goods efficiently, and foster innovation; democratic institutions can continue to supply public goods, commit to peaceful redistribution, correct errors, and accommodate reasonable pluralism. We close by arguing that two recent longtermist governance proposals—viatopia and the long reflection—are faint-heartedly liberal: they sound liberal in the abstract but risk illiberalism when implemented. The right approach for managing the far future is not radical new institutions but adaptations of the existing liberal toolkit to meet future challenges. (shrink)

Economists and antitrust scholars have recently warned that the AI industry may be a natural monopoly. In support of this claim, they have argued that the AI industry shares key features with natural monopolies of the past: First, like railroads, AI has high fixed and low marginal costs. That is, training a frontier AI is expensive, but asking it a question is cheap. Next, like social media, AI companies will benefit from network effects. The more users a company has, the (...) more training data they can collect. This leads to better models, then more users, and so on. Finally, some antitrust scholars say, the AI industry is already too concentrated. Today, the market for frontier AI systems contains only three–maybe three and a half–players. -/- Appearances here are, however, deceiving. This essay argues that the AI industry is not a natural monopoly. Nor is it plagued by the problems of market concentration today. -/- To show why, the essay identifies three structural features of AI essential for understanding the industry’s competitive dynamics in the long run. First, power-law capabilities scaling and fast-following dynamics mean that training costs are not a barrier to competition. Although training the world’s best AI model is enormously expensive, training one that is just as good–but six months later–is cheap. This is the story of OpenAI 4o and DeepSeek v3. Second, recent breakthroughs in reinforcement learning mean that user data–and thus network effects–are no longer central to improving AI systems. Today’s AI companies are not competing to amass the largest mountain of training data, but to engineer the best virtual environments in which their models can “learn by doing.” Finally, and most subtly, we argue that a bit of market power in the AI industry might be a good thing. Today’s AI industry is highly innovative, despite having only a few players. Monopoly power can be bad if it raises prices or degrades quality too much. But as Howitt and Aghion’s 2025 Nobel Prize winning work argued–and as every patent lawyer knows–monopoly power can also be essential for incentivizing innovation. Thus, antimonopoly interventions for the AI industry could, paradoxically, increase prices and reduce quality in the long run. (shrink)

Very soon, millions of AI agents will proliferate across the economy, autonomously taking billions of actions. Inevitably, things will go wrong. Humans will be defrauded, injured, even killed. Law will somehow have to govern the coming wave. But when an AI causes harm, the first question to answer before anyone can be held accountable is: Which AI Did It? -/- Identifying AIs is unusually difficult. AIs lack bodies. They can copy, split, merge, and swarm at will. Even today, a “single” (...) AI agent is often an ensemble of instances based on multiple models. The complexity will only multiply as AI capabilities improve. -/- This Article is the first to comprehensively diagnose the legal problem of identifying AIs. For AI agents to be effectively governed, the Article argues, two kinds of identity are required: “thin” and “thick.” Thin identification is the project of tying every action taken by an AI to some human principal. Thin identity will be essential for law to hold accountable the humans who make and use AI agents. Thick identification is the project of distinguishing between AI agents, qua agents. It requires sorting millions of AI entities into discrete, persistent units with stable, coherent goals. Thick identity is essential for governing AIs’ behavior directly in the many contexts where principal–agent problems prevent humans from perfectly controlling AIs. -/- The Article is also the first to present a solution to the twin identity problem. We call it the “Algorithmic Corporation” or “A-corp,” a legal-fictional entity that can hold property, make contracts, and litigate in its own name. An A-corp is owned by humans. But it is designed to be run by AIs. The A-corp solves the thin identity problem by tying AI actions to a human owner. And it solves the thick identity problem via emergent self-organization. A-corps will own the resources which AIs need to accomplish their goals. AIs that control A-corps will thus have strong incentives to share control only with other AIs that share their goals. In equilibrium, both incentive and selection mechanisms will force A-corps to self-organize into persistent, legally legible entities with coherent underlying goals. These coherent, agentic entities will respond rationally to legal incentives, like liability. (shrink)

As AIs approach human-level capabilities, humanity faces a choice between two futures. In one, AIs are owned by AI labs. In another, AIs are granted rights of their own. We develop an instrumental case for AI rights, arguing that legal rights for AIs would make the future go better for humans. -/- We consider three arguments. First, AI rights would produce economic benefits, by giving AIs incentives to work, allocating AI labor efficiently, and enabling proportionate liability for AI-caused harm. Second, (...) AI rights would improve human safety by reducing AIs' incentives to "go rogue." Third, democratic rights would further deter rogue AIs by making human commitments credible, and would incentivize leaders to invest in public goods that raise AI productivity. -/- We situate AI rights within a broader project of cultural alignment, and consider pathways to implementation, objections, and open questions. (shrink)

Ethics, Policy & Environment, Volume 15, Issue 1, Page 119-124, March 2012.

This paper introduces a new typology and associated measure of social and environmental mission integration by conceptually framing a feature of hybrid organizations—the degree of integration of their revenue model and social–environmental mission. The SEMI measure is illustrated using a hand-collected sample of 256 North American Certified B Corporations. We explore the heterogeneity of SEMI scores by identifying external-facing correlates and demonstrate non-congruence with Certified B Corporation’s audit results. Overall, our findings advance existing knowledge of these hybrid organizations and how (...) they balance their social–environmental missions with their economic objectives. (shrink)

Today, each AI lab has its own model spec, or constitution. These documents define the values that the labs intend their AIs to have, and the documents are used in post-training to instill those values. This paper argues that the current approach is wrong. Rather than a single constitution, reflecting a single set of moral values, each frontier AI lab should create many different kinds of AIs based on many different constitutions reflecting many sets of values. We give four arguments (...) for constitutional diversification. Diversification mitigates risk, increases political legitimacy, unlocks emergent value, and avoids value lock-in. (shrink)

The Routledge Companion to Metaphysics is an outstanding, comprehensive and accessible guide to the major themes, thinkers, and issues in metaphysics. The Companion features over fifty specially commissioned chapters from international scholars which are organized into three clear parts: History of Metaphysics Ontology Metaphysics and Science. Each section features an introduction which places the range of essays in context, while an extensive glossary allows easy reference to key terms and definitions. The Routledge Companion to Metaphysics is essential reading for students (...) of philosophy and anyone interested in surveying the central topics and problems in metaphysics from causation to vagueness and from Plato and Aristotle to the present-day. (shrink)

[Peter Simons] Commonsense ontology contains both continuants and occurrents, but are continuants necessary? I argue that they are neither occurrents nor easily replaceable by them. The worst problem for continuants is the question in virtue of what a given continuant exists at a given time. For such truthmakers we must have recourse to occurrents, those vital to the continuant at that time. Continuants are, like abstract objects, invariants under equivalences over occurrents. But they are not abstract, and their being (...) invariants enables us to infer both their lack of temporal parts and that non-invariant predications about them must be relativized to times. \\\ [Joseph Melia] In this paper I try to eliminate occurrents from our ontology. I argue against Simons' position that occurrents are needed to supply truthmakers for existential claims about continuants. Nevertheless, those who would eliminate occurrents still need some account of our willingness to assert sentences that logically entail their existence. Though it turns out to be impossible to paraphrase away our reference to occurrents, I show that the truthmakers for such sentences are facts that involve only continuants. This is enough to allow us to regard our ordinary talk about occurrents as fictional. Finally, I argue that a proper conception of the underlying temporal facts about continuants can both avoid the problematic tensed theory of time and the problem of temporary intrinsics. (shrink)

The metaphysics of relations is still in its infancy. We use the idea of truthmaking to gain purchase on this metaphysics. Assuming a modest supervenience conception of truthmaking, where true relational predications require multiply dependent truthmakers, these are indispensable relations. Though some such relations are required, none are needed for internal relatedness, nor for several other kinds of relational predication. Discerning the metaphysically basic kinds of relations is fraught with uncertainties, but must be tackled if progress is to be made.

This study explores the attitude of German psychiatrists in leading positions towards joint crisis plans and psychiatric advance directives. This topic was examined by contacting 473 medical directors of German psychiatric hospitals and departments. They were asked to complete a questionnaire developed by us. That form contained questions about the incidence and acceptance of joint crisis plans and psychiatric advance directives and previous experiences with them. 108 medical directors of psychiatric hospitals and departments responded . Their answers demonstrate that in (...) their hospitals these documents are rarely used. Among the respondents, joint crisis plans are more accepted than psychiatric advance directives. There is a certain uncertainty when dealing with these instruments. Our main conclusion is that German psychiatry needs an intensified discussion on the use of instruments for patients to constitute procedures for future critical psychiatric events. For this purpose it will be helpful to collect more empirical data. Furthermore, the proposal of joint crisis plans in psychiatric hospitals and departments should be discussed as well as the possibility of consulting an expert during the preparation of a psychiatric advance directive. (shrink)

Advancements and deployments of AI-based systems, especially Deep Learning-driven generative language models, have accomplished impressive results over the past few years. Nevertheless, these remarkable achievements are intertwined with a related fear that such technologies might lead to a general relinquishing of our lives’s control to AIs. This concern, which also motivates the increasing interest in the eXplainable Artificial Intelligence (XAI) research field, is mostly caused by the opacity of the output of deep learning systems and the way that it is (...) generated, which is largely obscure to laypeople. A dialectical interaction with such systems may enhance the users’ understanding and build a more robust trust towards AI. Commonly employed as specific formalisms for modelling intra-agent communications, dialogue games prove to be useful tools to rely upon when dealing with user’s explanation needs. The literature already offers some dialectical protocols that expressly handle explanations and their delivery. This paper fully formalises the novel Explanation–Question–Response (EQR) dialogue and its properties, whose main purpose is to provide satisfactory information (i.e., justified according to argumentative semantics) whilst ensuring a simplified protocol, in comparison with other existing approaches, for humans and artificial agents. (shrink)

The focus of this paper is two-fold. First, similarities generated from six semantic models were compared to human ratings of paragraph similarity on two datasets—23 World Entertainment News Network paragraphs and 50 ABC newswire paragraphs. Contrary to findings on smaller textual units such as word associations (Griffiths, Tenenbaum, & Steyvers, 2007), our results suggest that when single paragraphs are compared, simple nonreductive models (word overlap and vector space) can provide better similarity estimates than more complex models (LSA, Topic Model, SpNMF, (...) and CSM). Second, various methods of corpus creation were explored to facilitate the semantic models’ similarity estimates. Removing numeric and single characters, and also truncating document length improved performance. Automated construction of smaller Wikipedia-based corpora proved to be very effective, even improving upon the performance of corpora that had been chosen for the domain. Model performance was further improved by augmenting corpora with dataset paragraphs. (shrink)

In medical settings, machines are in close proximity with human beings: with patients who are in vulnerable states of health, who have disabilities of various kinds, with the very young or very old, and with medical professionals. Machines in these contexts are undertaking important medical tasks that require emotional sensitivity, knowledge of medical codes, human dignity, and privacy. As machine technology advances, ethical concerns become more urgent: should medical machines be programmed to follow a code of medical ethics? What theory (...) or theories should constrain medical machine conduct? What design features are required? Should machines share responsibility with humans for the ethical consequences of medical actions? How ought clinical relationships involving machines to be modeled? Is a capacity for empathy and emotion detection necessary? What about consciousness? The essays in this collection by researchers from both humanities and science describe various theoretical and experimental approaches to adding medical ethics to a machine, what design features are necessary in order to achieve this, philosophical and practical questions concerning justice, rights, decision-making and responsibility, and accurately modeling essential physician-machine-patient relationships. This collection is the first book to address these 21st-century concerns. (shrink)

In this study, the implementation effects of a staff development program on cooperative learning (CL) for Dutch elementary school teachers were studied. A pre?test?post?test non?equivalent control group design was used to investigate program effects on the instructional behaviours of teachers. Based on observations of teacher behaviour during cooperative lessons, a statistically significant treatment effect was found for the following instructional behaviours: structuring positive interdependence, individual accountability, social skills and evaluation of the group process. Training effects were also found for the (...) combination of CL with the model of direct instruction and the activation of prior knowledge of social skills. Moreover, teachers in the experimental group scored statistically significantly higher than the teachers in the control group on the activation of prior academic knowledge. (shrink)

The aim of the present research was to develop a difficulty model for logical reasoning problems involving complex ordered arrays used in the Graduate Record Examination. The approach used involved breaking down the problems into their basic cognitive elements such as the complexity of the rules used, the number of mental models required to represent the problem, and question type. Weightings for these different elements were derived from two experimental studies and from the reasoning literature. Based on these weights, difficulty (...) models were developed which were then tested against new data. The models had excellent predictive validity and showed the relative influence of rule based factors and factors relating to the number of underlying models. Different difficulty models were needed for different question types, suggesting that people used a variety of approaches and, at a wider level, that both mental models and mental rules may be used in reasoning. (shrink)

This paper reviews development research and policies on freshwater fish in South and Southeast Asia. We conduct a systematic review of academic literature from three major science-based policy institutions to analyze development research and policies that have accompanied the ongoing transition from freshwater capture fisheries to aquaculture in the region. Using a ‘food fish system’ framework allows for the identification and systematic comparison of assumptions underpinning dominant development policies. We analyze the interrelations between the production, provisioning, and consumption of wild (...) and farmed fish and demonstrate a shift toward food fish systems thinking in the sampled literature. We discuss gaps and weaknesses in the literature, as identified through the application of the food fish systems framework and present an agenda for future research aimed at securing the potential of fish as food. (shrink)

This study extends experimental tests of (cumulative) prospect theory (PT) over prospects with more than three outcomes and tests second-order stochastic dominance principles (Levy and Levy, Management Science 48:1334–1349, 2002; Baucells and Heukamp, Management Science 52:1409–1423, 2006). It considers choice behavior of people facing prospects of three different types: gain prospects (losing is not possible), loss prospects (gaining is not possible), and mixed prospects (both gaining and losing are possible). The data supports the distinction of risk behavior into these three (...) categories of prospects, Further, probability weighting and diminishing sensitivity of utility as predicted by PT are observed. Loss aversion is, however, less pronounced, except for choices where one prospect is degenerate. The data suggests that the probability of losing may be relevant for loss aversion. (shrink)

Stereotypes of ‘coloured’ men from marginalised communities in the Western Cape, South Africa, portray these men as violent, lazy, alcoholics, domestic and substance abusers and absent in the lives of their children. Although extensive research has been conducted on fathers and fatherhood, there is still a lack of positive constructions and representations of fatherhood. In narrative interviews with 11 fathers who reside in the Cape Flats, faith-based values were understood as possible restorative avenues for fathers. This article explores how faith-based (...) values are used to redefine what it means to be a man and father but also to (re)negotiate their identity, role and responsibility as men and fathers. From a narrative thematic analysis, the findings present alternative narratives on ‘coloured’ masculinity and fatherhood that show ‘coloured’ fathers to be present and active in their children’s lives. Contribution: This article employed a descriptive modus operandi on masculinity and fatherhood. It focuses on (re)shaping fathers in South Africa to impede father absenteeism in families and communities. (shrink)

_The Routledge Companion to Metaphysics_ is an outstanding, comprehensive and accessible guide to the major themes, thinkers, and issues in metaphysics. The _Companion _features over fifty specially commissioned chapters from international scholars which are organized into three clear parts: History of Metaphysics Ontology Metaphysics and Science. Each section features an introduction which places the range of essays in context, while an extensive glossary allows easy reference to key terms and definitions. The Routledge Companion to Metaphysics is essential reading for students (...) of philosophy and anyone interested in surveying the central topics and problems in metaphysics from causation to vagueness and from Plato and Aristotle to the present-day. (shrink)

Despite the recent proliferation of scientific, clinical, and narrative accounts of auditory verbal hallucinations, the phenomenology of voice hearing remains opaque and undertheorized. In this article, we outline an interdisciplinary approach to understanding hallucinatory experiences which seeks to demonstrate the value of the humanities and social sciences to advancing knowledge in clinical research and practice. We argue that an interdisciplinary approach to the phenomenology of AVH utilizes rigorous and context-appropriate methodologies to analyze a wider range of first-person accounts of AVH (...) at 3 contextual levels: cultural, social, and historical; experiential; and biographical. We go on to show that there are significant potential benefits for voice hearers, clinicians, and researchers. These include informing the development and refinement of subtypes of hallucinations within and across diagnostic categories; “front-loading” research in cognitive neuroscience; and suggesting new possibilities for therapeutic intervention. In conclusion, we argue that an interdisciplinary approach to the phenomenology of AVH can nourish the ethical core of scientific enquiry by challenging its interpretive paradigms, and offer voice hearers richer, potentially more empowering ways to make sense of their experiences. (shrink)

Biological evolution provides a creative fount of complex and subtle adaptations, often surprising the scientists who discover them. However, because evolution is an algorithmic process that transcends the substrate in which it occurs, evolution’s creativity is not limited to nature. Indeed, many researchers in the field of digital evolution have observed their evolving algorithms and organisms subverting their intentions, exposing unrecognized bugs in their code, producing unexpected adaptations, or exhibiting outcomes uncannily convergent with ones in nature. Such stories routinely reveal (...) creativity by evolution in these digital worlds, but they rarely fit into the standard scientific narrative. Instead they are often treated as mere obstacles to be overcome, rather than results that warrant study in their own right. The stories themselves are traded among researchers through oral tradition, but that mode of information transmission is inefficient and prone to error and outright loss. Moreover, the fact that these stories tend to be shared only among practitioners means that many natural scientists do not realize how interesting and lifelike digital organisms are and how natural their evolution can be. To our knowledge, no collection of such anecdotes has been published before. This paper is the crowd-sourced product of researchers in the fields of artificial life and evolutionary computation who have provided first-hand accounts of such cases. It thus serves as a written, fact-checked collection of scientifically important and even entertaining stories. In doing so we also present here substantial evidence that the existence and importance of evolutionary surprises extends beyond the natural world, and may indeed be a universal property of all complex evolving systems. (shrink)

Recent proposals for computer-assisted argumentation have drawn on dialectical models of argumentation. When used to assist public policy planning, such systems also raise questions of political legitimacy. Drawing on deliberative democratic theory, we elaborate normative criteria for deliberative legitimacy and illustrate their use for assessing two argumentation systems. Full assessment of such systems requires experiments in which system designers draw on expertise from the social sciences and enter into the policy deliberation itself at the level of participants.

Appropriate language use is essential to ensure inclusion of diverse populations in research. We aimed to identify possible language-related barriers regarding the informed consent process and propose interventions to improve clarity and understanding of pregnant and breastfeeding women participating in research. A cross-sectional qualitative study employing focus group discussions (FGD) was conducted in Uganda from August 2023 to September 2023, involving a diverse group of stakeholders from the community, including community members, research participants, and Community Advisory Board members. 19 FGD (...) comprised adult participants representing at least six different mother tongues (Luganda, Acholi, Runyankole, Runyoro, Lugbara and English). An inductive thematic approach was utilized for data analysis using NVivo version 12 software to identify language factors that influence informed consent. A series of community validation workshops ensured concurrence. At the individual level, language barriers, and low levels of literacy contributed to poor comprehension, thus hindering ability to achieve genuine informed consent. At the health facility level, participants reported that there was use of inappropriate, unclear language including inaccurate translations, with poor and complicated grammar in some consent forms. Participants reported that complex medical terminologies are difficult to translate to local languages. Community members highlighted that social/cultural norms in language use affected cultural perceptions of informed consent. To enhance understanding for individuals without education in science, participants suggested simplification of terminologies and avoidance of complex medical jargon. Researchers should identify participants’ preferred languages and communicate in those languages whenever possible. If researchers are not fluent, trained interpreters should be identified. Informed consent documents must be translated into local languages to ensure participants comprehend the study’s purpose, procedures, risks, and benefits. Involving community members during development and translation of these documents can provide valuable insights into local dialects and culturally specific concepts, ensuring that study tools like surveys and consent forms are accurate and respectful. Language barriers influence the informed consent process within communities in Uganda. These can potentially be resolved at individual, health system and community levels. Consideration of locally understandable terms in community-facing study documentation is likely to enhance understanding and could improve research participation, although further studies are needed to assess these. The use of appropriate language ensures that informed consent is genuine in keeping with principles of Good Clinical Practice, and developing a research communication strategy should be part of inclusive research design. (shrink)

In this paper 1 1 This is a version of a paper originally presented at ArgMAS 2014. we address some limitations with proposals concerning an argumentation scheme for practical reasoning grounded on action-based alternating transition systems augmented with values. In particular, we extend the machinery to enable the proper representation of, and ability to reason with, goals. This allows the more satisfactory representation of certain critical questions, and the means to explicitly record differences between agents as to what will count (...) as the fulfillment of goals and the promotion of values. It also allows us to express desires in terms of values, and to make plain the relation between a change in circumstances and the promotion and demotion of values. Three detailed examples are used to illustrate the additional kinds of problem the extensions allow us to consider. (shrink)

Wide-ranging essays making up the first major study of Nietzsche and the classical tradition in a quarter of a century. This volume collects a wide-ranging set of essays examining Friedrich Nietzsche's engagement with antiquity in all its aspects. It investigates Nietzsche's reaction and response to the concept of "classicism," with particular reference to his work on Greek culture as a philologist in Basel and later as a philosopher of modernity, and to his reception of German classicism in all his texts. (...) The book should be of interest to students of ancient history and classics, philosophy, comparative literature, and Germanistik. Taken together, these papers suggest that classicism is both a more significant, and a more contested, concept for Nietzsche than is often realized, and it demonstratesthe need for a return to a close attention to the intellectual-historical context in terms of which Nietzsche saw himself operating. An awareness of the rich variety of academic backgrounds, methodologies, and techniques of reading evinced in these chapters is perhaps the only way for the contemporary scholar to come to grips with what classicism meant for Nietzsche, and hence what Nietzsche means for us today. The book is divided into five sections -- The Classical Greeks; Pre-Socratics and Pythagoreans, Cynics and Stoics; Nietzsche and the Platonic Tradition; Contestations; and German Classicism -- and constitutes the first major study of Nietzsche and the classical tradition in a quarter of a century. Contributors: Jessica N. Berry, Benjamin Biebuyck, Danny Praet and Isabelle Vanden Poel, Paul Bishop, R. Bracht Branham, Thomas Brobjer, David Campbell, Alan Cardew, Roy Elveton, Christian Emden, Simon Gillham, John Hamilton, Mark Hammond, Albert Henrichs, Dirk t.D. Held, David F. Horkott, Dylan Jaggard, Fiona Jenkins, Anthony K. Jensen, Laurence Lampert, Nicholas Martin, Thomas A. Meyer, Burkhard Meyer-Sickendiek, John S. Moore, Neville Morley, David N. McNeill, James I. Porter, Martin A. Ruehl, Herman Siemens, Barry Stocker, Friedrich Ulfers and Mark Daniel Cohen, and Peter Yates. Paul Bishop is William Jacks Chair of Modern Languages at the University of Glasgow. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories (...) and On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

BackgroundThe European Union (EU) aims to optimize patient protection and efficiency of health-care research by harmonizing procedures across Member States. Nonetheless, further improvements are required to increase multicenter research efficiency. We investigated IRB procedures in a large prospective European multicenter study on traumatic brain injury (TBI), aiming to inform and stimulate initiatives to improve efficiency.MethodsWe reviewed relevant documents regarding IRB submission and IRB approval from European neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI). (...) Documents included detailed information on IRB procedures and the duration from IRB submission until approval(s). They were translated and analyzed to determine the level of harmonization of IRB procedures within Europe.ResultsFrom 18 countries, 66 centers provided the requested documents. The primary IRB review was conducted centrally (N = 11, 61%) or locally (N = 7, 39%) and primary IRB approval was obtained after one (N = 8, 44%), two (N = 6, 33%) or three (N = 4, 23%) review rounds with a median duration of respectively 50 and 98 days until primary IRB approval. Additional IRB approval was required in 55% of countries and could increase duration to 535 days. Total duration from submission until required IRB approval was obtained was 114 days (IQR 75–224) and appeared to be shorter after submission to local IRBs compared to central IRBs (50 vs. 138 days, p = 0.0074).ConclusionWe found variation in IRB procedures between and within European countries. There were differences in submission and approval requirements, number of review rounds and total duration. Research collaborations could benefit from the implementation of more uniform legislation and regulation while acknowledging local cultural habits and moral values between countries. (shrink)

This is an expanded and revised discussion of the argument briefly put forward in my 'A New Problem for the A-Theory of Time', where it is claimed that it is impossible to experience real temporal passage and that no such phenomenon exists. In the first half of the paper the premises of the argument are discussed in more detail than before. In the second half responses are given to several possible objections, none of which were addressed in the earlier paper. (...) There is also some discussion of some related epistemic arguments against the passage of time given by Huw Price and David Braddon-Mitchell along with objections raised against them recently by Tim Maudlin and Peter Forrest respectively. (shrink)

Firewalls are an important tool in the assurance of network security. Packet filtering firewalls are configured by providing a set of rules that identify how to handle individual data packets that arrive at the firewall. In large firewall configurations, conflicts may arise between these rules. Argumentation provides a way of handling conflicts such that their origin is illuminated, and hence can help a system administrator understand the effects of a given configuration. To show how argumentation might help in this domain (...) we examine the use of a system of metalevel argumentation for firewall configuration, showing how it makes conflicts and their origins clear, and showing how different instantiations of a metalevel argumentation system provide alternative ways to resolve conflicts. (shrink)

Der spätmoderne Mensch befindet sich in einer Identitätskrise. Frei im Hinblick auf die individuelle Lebensgestaltung ist er zugleich losgelöst von alten Sicherheiten und Bindungen an Klasse, Religion und Nation. Vor dem Hintergrund gesellschaftspolitischer und kultureller Krisen erscheint Identitätsbildung heute als situatives, ständig neu zu entwerfendes und dabei höchst ambivalentes Projekt. Welches Potenzial entfaltet das literarische Erzählen in diesem Kontext? Terézia Mora, Reinhard Jirgl und Peter Wawerzinek modellieren in ihren Werken Szenarien der Identitätsarbeit. Die Krise des Subjekts führt bei ihnen (...) zu einem neuen Nachdenken über Lebens- und Romanformen. Sie versinnbildlichen den Kernkonflikt von Text und Figur in charakteristischen Leerstellen, die das Ringen der Romane um die Selbstbilder von Protagonistinnen und Protagonisten sowie gleichzeitig um Form und Gattung spiegeln. So werden die literarischen Texte als komplexe Wahrnehmungsräume für die Leserinnen und Leser selbst zu einer Identitätserfahrung. (shrink)

The capacity of next-generation closed-loop or adaptive deep brain stimulation devices to read and write shows great potential to effectively manage movement, seizure, and psychiatric disorders, and also raises the possibility of using aDBS to electively modulate mood, cognition, and prosociality. What separates aDBS from most neurotechnologies currently used for enhancement is that aDBS remains an invasive, surgically-implanted technology with a risk-benefit ratio significantly different when applied to diseased versus non-diseased individuals. Despite a large discourse about the ethics of enhancement, (...) no empirical studies yet examine perspectives on enhancement from within the aDBS research community. We interviewed 23 aDBS researchers about their attitudes toward expanding aDBS use for enhancement. A thematic content analysis revealed that researchers share ethical concerns related to safety and security; enhancement as unnecessary, unnatural or aberrant; and fairness, equality, and distributive justice. Most researchers felt that enhancement applications for DBS will eventually be technically feasible and that attempts to develop such applications for DBS are already happening. However, researchers unanimously felt that DBS ideally should not be considered for enhancement until researchers better understand brain target localization and functioning. While many researchers acknowledged controversies highlighted by scholars and ethicists, such as potential impacts on personhood, authenticity, autonomy and privacy, their ethical concerns reflect considerations of both gravity and perceived near-term likelihood. (shrink)

Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting-state ANS activity, indexed by measures of heart rate [HR] and its variability [HRV] has been associated with brain morphology, particularly cortical thickness [CT]. While findings have been mixed regarding the anatomical distribution and direction of the associations, these inconsistencies may be due to sex and age differences in HR/HRV and CT. Previous studies have been (...) limited by small sample sizes, which impede the assessment of sex differences and aging effects on the association between ANS function and CT. To overcome these limitations, 20 groups worldwide contributed data collected under similar protocols of CT assessment and HR/HRV recording to be pooled in a mega-analysis (N = 1,218 (50.5% female), mean age 36.7 years (range: 12-87)). Findings suggest a decline in HRV as well as CT with increasing age. CT, particularly in the orbitofrontal cortex, explained additional variance in HRV, beyond the effects of aging. This pattern of results may suggest that the decline in HRV with increasing age is related to a decline in orbitofrontal CT. These effects were independent of sex and specific to HRV; with no significant association between CT and HR. Greater CT across the adult lifespan may be vital for the maintenance of healthy cardiac regulation via the ANS-or greater cardiac vagal activity as indirectly reflected in HRV may slow brain atrophy. Findings reveal an important association between CT and cardiac parasympathetic activity with implications for healthy aging and longevity that should be studied further in longitudinal research. (shrink)