Արտակարգ վիճակների ախտաֆիզիոլոգիաShock states
Some problems for thinking from Jim Russel (from Pathophysiology of Septic Shock, Russel et al., 2018):
Patients with septic shock are almost always hypovolemic to varying extents because of obvious fluid losses (diarrhea, vomiting) or increased insensitive losses (fever, tachypnea). In addition, as described, there may be ongoing fluid losses because of redistribution of fluid from the vascular to the extravascular space owing to increased vascular permeability. Direct measurement of the degree of fluid losses is not possible; a decline in plasma radiolabeled albumin can be used to measure protein loss and implied vascular permeability, but this is not feasible as a routine clinical tool. Hemoconcentration may be an indirect marker of such fluid redistribution, but does not address how much fluid has been redistributed.Ստայնբեքի սիրահարների համար․
The grapes and wrath: using resveratrol to treat the pathophysiology of hemorrhagic shock
