FlyBase Gene Report: Dmel\aPKC

enzymatic study, autoradiography

(Colosimo et al., 2010)

aPKC - Cdc42

anti bait coimmunoprecipitation, western blot, Identification by mass spectrometry, pull down, autoradiography

(Leibfried et al., 2013)

aPKC - Dap160

(Chabu and Doe, 2008)

aPKC - Magi

proximity ligation assay, fluorescence microscopy, anti bait coimmunoprecipitation, western blot

(Padash Barmchi et al., 2016)

aPKC - Myo10A

two hybrid, pull down, autoradiography

(Liu et al., 2008)

aPKC - Patj

pull down, western blot, anti tag western blot

(Sotillos et al., 2004)

aPKC - Rap1

anti tag coimmunoprecipitation, anti tag western blot

(Carmena et al., 2011)

aPKC - Tsp2A

(Xu et al., 2019)

aPKC - Vhl

enzymatic study, autoradiography

(Duchi et al., 2010)

aPKC - aurA

(Wirtz-Peitz et al., 2008)

aPKC - clu

phenotype-based detection assay, fluorescence microscopy, inferred by author, pull down, western blot, anti tag western blot

(Goh et al., 2013)

aPKC - crb

(Kempkens et al., 2006, Sotillos et al., 2004)

aPKC - dlg1

enzymatic study, Identification by mass spectrometry

(Golub et al., 2017)

aPKC - futsch

(Ruiz-Canada et al., 2004)

aPKC - fz

(Djiane et al., 2005)

aPKC - kibra

anti bait coimmunoprecipitation, western blot, experimental knowledge based, proximity ligation assay, fluorescence microscopy, anti tag coimmunoprecipitation, peptide massfingerprinting

(Jin et al., 2015)

aPKC - l(2)gl

(Portela et al., 2024, Calero-Cuenca et al., 2016, Goh et al., 2013, Guruharsha et al., 2011, Tian and Deng, 2008, Wirtz-Peitz et al., 2008, Betschinger et al., 2003)

aPKC - mira

anti bait coimmunoprecipitation, western blot, enzymatic study, autoradiography, pull down, anti tag coimmunoprecipitation, anti tag western blot

(Atwood and Prehoda, 2009, Wirtz-Peitz et al., 2008)

aPKC - mts

anti tag coimmunoprecipitation, anti tag western blot, anti bait coimmunoprecipitation, western blot

(Chabu and Doe, 2009, Ogawa et al., 2009)

aPKC - nuf

pull down, western blot, protein kinase assay, autoradiography, anti tag coimmunoprecipitation, peptide massfingerprinting

(Calero-Cuenca et al., 2016)

aPKC - numb

pull down, western blot

(Wirtz-Peitz et al., 2008)

aPKC - par-1

anti tag coimmunoprecipitation, peptide massfingerprinting, western blot

(Calero-Cuenca et al., 2016, Tian and Deng, 2008)

aPKC - pbl

anti bait coimmunoprecipitation, anti tag western blot

(Rosa et al., 2015)

aPKC - pon

pull down, western blot

(Wirtz-Peitz et al., 2008)

aPKC - ref(2)P

(Avila et al., 2002)

aPKC - sdt

anti tag coimmunoprecipitation, anti tag western blot, anti bait coimmunoprecipitation

(Koch et al., 2016)

aPKC - sif

(Wang et al., 2018)

aPKC - tws

(Chabu and Doe, 2009)

aPKC - wupA

enzymatic study, autoradiography, peptide massfingerprinting, anti bait coimmunoprecipitation, western blot, pull down

(Casas-Tintó and Ferrús, 2019)

aPKC - yrt

(Gamblin et al., 2014)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

arm

(Kaplan et al., 2011)

suppressible

baz

(Jiang et al., 2015)

suppressible

Dhc64C

(Jiang et al., 2015)

enhanceable

Egfr

(Tian et al., 2023)

enhanceable

eIF4E5

(Shao et al., 2023)

suppressible

(Lee et al., 2006)

enhanceable

(Ogawa et al., 2009)

enhanceable

numb

(Wirtz-Peitz et al., 2008)

suppressible

numb

(Haenfler et al., 2012, Wirtz-Peitz et al., 2008)

enhanceable

(Xu et al., 2014)

suppressible

(Jiang et al., 2015)

suppressible

pins

(Guilgur et al., 2012)

arm|aPKC

enhanceable

sgg

(Kaplan et al., 2011)

enhanceable

sgg|arm

(Kaplan et al., 2011)

suppressible

Su(Tpl)|lilli

(Liu et al., 2017)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

arm

enhanceable

aPKC|sgg

(Kaplan et al., 2011)

aurA

suppressible

(Wang et al., 2006)

baz

enhanceable

(Shao et al., 2010)

baz

suppressible

(Heiden et al., 2021)

cactin

suppressible

(Miao et al., 2022)

crb

suppressible

(Sotillos et al., 2004)

cyst

enhanceable

(Silver et al., 2019)

suppressible

(Ma et al., 2009)

suppressible

(Uttekar et al., 2024)

eIF4E5

enhanceable

(Shao et al., 2023)

Fmr1

suppressible

(Zarnescu et al., 2005)

hoka

suppressible

(Izumi et al., 2021)

l(2)gl

suppressible

(Haenfler et al., 2012, Atwood and Prehoda, 2009, Lee et al., 2006, Rolls et al., 2003)

l(2)gl

enhanceable

(Rolls et al., 2003)

peb

suppressible

(Wilk et al., 2004)

Pfdn2

suppressible

(Zhang et al., 2016)

suppressible

(Fic et al., 2021)

enhanceable

(Kaplan et al., 2011)

sgg|arm

enhanceable

(Kaplan et al., 2011)

slmb

suppressible

(Morais-de-Sá et al., 2014, Skwarek et al., 2014)

Syx7

suppressible

(Lu and Bilder, 2005)

tws

suppressible

(Chabu and Doe, 2009)

Zif

suppressible

(Chang et al., 2010)

zip

enhanceable