FlyBase Allele Report: Scer\GAL4[MsrA.657]

General Information

Symbol

Scer\GAL4^MsrA.657

Species

S. cerevisiae

Name

FlyBase ID

FBal0141520

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{MsrA-GAL4.657}

Also Known As

Eip71CD-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Cherbas et al., 2003, Cherbas, 2002.12)

Progenitor genotype

Carried in construct

P{MsrA-GAL4.657}

Cytology

Description

Eip71CD promoter sequences from -657bp to +11bp regulate expression of a GAL4 driver.

(Cherbas et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

MsrA

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval epidermis

(Bloomington Drosophila Stock Center, 2017, Kester and Nambu, 2011)

larval brain | restricted

(Bloomington Drosophila Stock Center, 2017)

larval brain

(Kester and Nambu, 2011)

wandering third instar larval stage

salivary gland

(Cherbas et al., 2003)

Additional Information

Statement

Reference

ScerGAL4^Eip71CD.657 drives expression in the larval epidermis and in brain cells starting at the mid-third instar transition.

(Bloomington Drosophila Stock Center, 2017)

Expressed in the larval epidermis and in brain cells starting at the mid-third instar transition.

(Kester and Nambu, 2011)

Expression is observed at the mid-third instar transition in the salivary glands.

(Cherbas et al., 2003)

Marker for

Reflects expression of

MsrA

(Bloomington Drosophila Stock Center, 2017, Cherbas et al., 2003)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body size | P-stage, with EcR^GD1428

(Heredia et al., 2021)

abnormal body size | P-stage, with Ilp8^HMS06016, Scer\GAL4^A58

(Heredia et al., 2021)

abnormal circadian rhythm | adult stage, with Cpes^RNAi.UAS.IR1

(Chen et al., 2022)

abnormal eclosion, with Scer\GAL4^btl.PS, cPges^KK111193

(Fujinaga et al., 2025)

abnormal heat stress response | larval stage, with Phae1^KK106428

(Matsumura et al., 2025)

lethal - all die before end of larval stage, with Cyp18a1^UAS.cGa

(Scanlan and Robin, 2024)

lethal - all die before end of P-stage, with wall^EY20330

(Scanlan and Robin, 2024)

lethal - all die before end of P-stage, with wall^UAS.pU

(Scanlan and Robin, 2024)

lethal - all die before end of pupal stage, with Atf3^UAS.cSa

(Sekyrova et al., 2010)

lethal - all die during pupal stage, with spg^{RNAi.1447-1632.UAS}

(Eguchi et al., 2013)

some die during pharate adult stage, with Scer\GAL4^btl.PS, cPges^KK111193

(Fujinaga et al., 2025)

some die during pupal stage, with Atf3^UAS.cSa

(Sekyrova et al., 2010)

some die during pupal stage, with Scer\GAL4^btl.PS, cPges^KK111193

(Fujinaga et al., 2025)

visible, with Atf3^UAS.cSa

(Sekyrova et al., 2010)

Phenotype Manifest In

adult abdomen | dorsal, with Atf3^UAS.cSa

(Sekyrova et al., 2010)

adult cuticle | dorsal, with Atf3^UAS.cSa

(Sekyrova et al., 2010)

imaginal disc, with EcR^{B1-ΔC655.F645A.UAS}

(Cherbas et al., 2003)

pupa, with EcR^{B1-ΔC655.F645A.UAS}

(Cherbas et al., 2003)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Hsap\PTGES3^UAS.cFa/Scer\GAL4^MsrA.657 is a suppressor of lethal - all die before end of P-stage | recessive phenotype of cPges^KO

(Fujinaga et al., 2025)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

cPges^{UAS.Tag:FLAG,Tag:HA}/Scer\GAL4^MsrA.657 rescues cPges^KO

(Fujinaga et al., 2025)

Fails to rescue

Pgr^{UAS.Tag:FLAG,Tag:HA}/Scer\GAL4^MsrA.657 fails to rescue Pgr^A1/Pgr^B1

(Fujinaga et al., 2025)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

6871

w¹¹¹⁸; P{MsrA-GAL4.657}TP1-1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Scer\GAL4^Eip71CD.657

Scer\GAL4^Eip71CD.PC

Scer\GAL4^MsrA.657

Name Synonyms

Secondary FlyBase IDs

References (15)

Report Sections

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