replicase

Our results indicated a relationship between genetic variation in the replicase gene (rep) and the geographic regions, as well as the feasibility of using the rep gene for virus detection and molecular epidemiology investigations.

What emerged were distinct classes of drug that targeted three major areas of the virus, namely the NS3/4A protease, the NS5A replicase and the NS5B polymerase.

DNA polymerase delta: a second eucaryotic DNA replicase. Bioessays 1990; 12: 231-236, doi: 10.1002/bies.950120507.

Based on amino acid sequences of RNA-dependent RNA polymerase (RdRp, replicase) and CP, Ivanov et al.

These nonstructural proteins are Coronaviridae-wide conserved domains in replicase polyprotein pp lab.

The NS5 protein is the largest viral protein; a larger C-terminal domain serves as the RNA-dependent RNA polymerase (replicase), whereas a smaller N-terminal domain functions as a methyltransferase that synthesizes the 50 cap on new genomic RNA strands.

The process starts when the virus produces replicase and once the translation inside the cell has taken place, the replicase is translated and any further translation is stopped by a stop codon.

Basener applies mathematical dynamic modeling analysis to evolution based on an extinction of human civilization and in vitro QP replicase experiments.

The IBD viruses like many RNA viruses evolve quickly because of the low proofreading activity of their viral replicase [10].