Resources for Researchers

NIAID offers many resources to support your research, including reagents, model organisms, and tissue samples, to name just a few. Use the filters under Filter Search Results to narrow your search, or simply enter specific search terms in the search field.

93 Results

NIAID’s controlled access, secure cloud-based data platform that provides sharing of and access to de-identified, participant-level data sets and related metadata from NIAID supported and other clinical research and trials. 

The ACTG NL consists of Core Laboratory groups in immunology, pharmacology, virology and TB.

The specimen repositories are a collaboration between the ACTG and IMPAACT clinical trial networks to make the large body of specimens collected for HIV research available to investigators.

The specimens stored at the repositories were initially collected for specific studies that have concluded, and are now available to investigators conducting new research.

Standard operating procedures for small animal models for fungal pathogens that are intended to help researchers establish and use these models and ensure uniform testing.

The ARLG biorepositories were created to aid in the development and evaluation of novel diagnostic tests and laboratory techniques, study mechanisms of resistance, generate preliminary data for study concepts, and support/mentor early-stage investigators pursuing research in the field of antibacterial resistance.

The BEI Resources Repository is a central repository that supplies organisms and reagents to the broad community of microbiology and infectious diseases researchers. Materials are available through an online catalog. There is no charge for research materials, but domestic investigators will be required to pay for shipping costs.

The NIAID-funded Bioinformatics Resource Centers provide data-driven, production-level, sustainable computational platforms to enable sharing and access to data, portable computational tools, and standards that support interoperability for the infectious diseases research community.

The Capacity-building Hubs to Enhance the Science of HIV Implementation REsearch (CHESHIRE) network advances rigorous implementation science by providing tailored support, cross-project information sharing, and technical assistance, rapidly accelerating implementation knowledge to end the HIV epidemic in

NIAID CEIRS provides the BEI Resources Repository with high-priority reagents from the CEIRS community. Reagents include plasmids, antibodies, proteins, and virus isolates. Reagents not available through BEI can be requested on this page. Non-BEI reagents may be available from CEIRS researchers upon request.

The CIBMTR database contains data on outcomes of hematopoietic (blood and bone marrow) cell transplant (HCT) procedures. The CIBMTR collaborates with government agencies, professional groups, international partners, and patient organizations via 15 active scientific/research working committees.

The Centers for Research on Structural Biology of Infectious Diseases (CRSTAL-ID) provide the research community with: 3-D protein structures and protein-ligand complexes; Sequence-verified clones and peptides; Services that deliver requested 3-D structure determination; and Molecular screening of proteins in complex with inhibitors, cofactors and substrate analogs

The ChemDB database contains information extracted from scientific literature on the structure and activity of compounds that have been tested against HIV, opportunistic pathogens, and TB. This database is continually updated with information extracted from published literature, including the chemical structure and biological activity of compounds.

 

The Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB) is a NIAID-led partnership with RTI International, which oversees the design, synthesis, and management of external investigator-submitted libraries of chemical compounds specifically targeting Gram-negative bacteria.

ClinRegs is an online database of country-specific clinical research regulatory information designed to assist in planning and implementing international clinical research. By providing well-documented and current information in a single place, ClinRegs serves as a central resource and time-saver for those involved in clinical research.

CARD is a comprehensive web-application for integrated analysis and interactive visualization of RNA interference (RNAi) screening data.

The RSC Public Website, run by the DAIDS Regulatory Support Center (RSC) contractor, has been used in the DAIDS community for over 15 years and is a primary platform to communicate updates to templates, process changes, and other information needed by the RSC research community.

The STAT3base contains a listing of STAT3 mutations in human HIES identified in the Laboratory of Clinical Immunology and Microbiology as well as those published in the literature.

NIAID’s Diagnostics Development Services program offers reagents, platform testing, and planning and design support to accelerate product development of in vitro diagnostics (IVD) for infectious diseases, from research feasibility through clinical validation.

The Early Phase Clinical Trial Units (EPCTUs) support the design, development, implementation, and conduct of Phase 0 to Phase 2 clinical trials, including proof-of-concept studies in healthy, special, and disease-specific populations, carried out in an expeditious and efficient manner, aided by bioanalysis when necessary, against viral, bacterial, parasitic, and fungal pathogens and

The Feasibility of Novel Diagnostics for TB in Endemic Countries (FEND for TB) program supports the evaluation of early-stage diagnostics and novel diagnostic strategies for TB, in TB endemic countries to address an urgent need for improved tuberculosis (TB) diagnostics.

The Filariasis Research Reagent Resource Center (FR3) maintains oversight of filarial parasites, SOPs, and molecular reagents. FR3 is comprised of two divisions: The Parasite Resource Division and the Molecular Resources Division.

Glucocorticoids are the cornerstone of anti-inflammatory and immunosuppressive therapy in humans. They are often the drugs of choice when rapid and potent control of an overactive immune system is necessary. This was exemplified recently by their successful use in the treatment of patients with severe COVID-19.

The GCID use, develop and improve innovative applications of genomic technologies, such as DNA and RNA sequencing and metagenomics, and provide rapid and cost-efficient production of high-quality genome sequences of microorganisms, invertebrate vectors of infectious diseases, and hosts and host microbiomes.

The Genomic Research Integration System (GRIS) Portal provides meaningful collaborative analysis of integrated clinical, family, and genomic data generated from the Clinical Genomics Program and its collaborators’ studies.

Hedwig is the major Electron Microscopy image repository in NIAID. Researchers can submit projects, process images, explore light microscopy data, and view and download their images and movies. Hedwig can also be used to run and manage a microscopy service lab.