Table of Contents
From the Editor
- Localized dead bone, a potential hint to an underlying condition
The discovery of osteonecrosis by imaging, whether the patient is symptomatic or not, warrants consideration for the presence of an underlying condition.
The Clinical Picture
- Sclerotic lesions in the metadiaphysis regions of the knee
The patient presented with left knee pain located over her patella that had progressively worsened over 4 months.
- An uncommon skin manifestation after radial artery catheterization
A rash developed over the dorsum of the patient’s right hand immediately after compression bands were placed over the radial arteriotomy site.
1-Minute Consult
- What screening approach could improve early detection of ‘at-risk’ metabolic dysfunction–associated steatohepatitis in my patients?
Screening for MASH follows a stepwise, sequential approach, beginning with calculation of the fibrosis-4 index
- Should I prescribe statins for primary prevention of cardiovascular disease in older adults?
This decision should reflect the patient’s biological age and functional status rather than chronological age alone.
Symptoms to Diagnosis
- A 70-year-old man with lower-extremity weakness and falls
After multiple imaging studies were performed, a thorough examination at the bedside appropriately broadened the differential diagnosis.
Review
Treatment-refractory hypothyroidism: Don’t just increase the doseA systematic diagnostic approach can avert the cascade of unnecessary dose escalations and laboratory testing and the morbidity of persistent hypothyroidism.
Letters to the Editor
Corrections
- A 20-year-old woman with a 9-year history of shortness of breath
The following article in the April 2026 issue contained an error: Johnson J, Lukose K, Labanowski MC. A 20-year-old woman with a 9-year history of shortness of breath Cleve Clin J Med 2026; 93(4):211–217, doi:10.3949/ccjm.93a.25073.
Commentary
Comfort care plans are always individualized and should naturally evolve as the patient’s clinical status changes.