Table of Contents
Practice Parameter
Review Articles
General Contents
- Neuroimaging Predictors of Futile Recanalization in Anterior Circulation Stroke: A Systematic Review and Meta-Analysis
This systematic review found that lower ASPECTS scores, impaired perfusion metrics (eg, high hypoperfusion intensity ratio, delayed venous outflow), poor collateral status, and markers of chronic brain injury (eg, leukoaraiosis and atrophy) were consistently linked to poor functional outcomes despite successful reperfusion with mechanical thrombectomy for acute ischemic stroke. Core infarct volume showed less consistent predictive value.
- Deep Learning Radiomics Signature from Multicontrast MRI for Automated Identification of Symptomatic Carotid Plaques: A Multicenter Study
This multicenter retrospective study developed and validated a deep learning radiomics model using multicontrast MRI to identify symptomatic carotid atherosclerotic plaques. The model demonstrated excellent performance, achieving AUROCs up to 0.975 and significantly outperforming clinical, radiomics-only, and deep learning–only models across training and validation cohorts. Its accuracy remained high across varying degrees of stenosis and correlated with higher risk plaque features.
- Microcirculatory Collaterals Modulate Ischemic Core Heterogeneity on Diffusion-Weighted Imaging
Collateral status influences tissue-level variability within the ischemic core. This study found that patients with favorable tissue-level collaterals (low hypoperfusion intensity ratio, HIR ≤0.5) had smaller infarct cores, lower stroke severity, and reduced ADC heterogeneity compared with those with unfavorable HIR. Despite similar mean ADC values, variability within the ischemic core was significantly lower in the favorable HIR group, and HIR was independently associated with ADC heterogeneity.
- MRI and Clinical Features of Nonenhancing IDH-Wild-Type Glioblastomas: How to Make an Early Diagnosis and Distinguish from Mimics
A subset of IDH-wild-type glioblastomas can initially appear as nonenhancing, T2 FLAIR hyperintense cortical lesions on MRI, which may lead to misdiagnosis and delayed treatment. This study found that features such as larger tumor size, restricted diffusion, and involvement of eloquent brain regions favored nonenhancing GBMs, while greater edema and certain imaging signs were more typical of nonmalignant mimics (logistic regression - AUC 0.89).
- Sinking Flap Syndrome: Risk Factors, Outcomes, and the Role of Neuroradiology in Cranioplasty Timing
This retrospective study evaluated the recognition and impact of sinking flap syndrome (SFS) in patients undergoing cranioplasty. Trauma, larger flap size (≥16 cm), and midline shift ≥8 mm were significant predictors of SFS, which was associated with worse clinical outcomes. Importantly, neuroradiologist identification of SFS significantly reduced time to cranioplasty without increasing complications, underscoring the value of early recognition and standardized diagnostic criteria.
- Incidence and Predictors of Rebound Intracranial Hypertension after Transvenous Embolization of CSF-Venous Fistulas
In this single-center retrospective study the incidence and severity of rebound intracranial hypertension after transvenous embolization for CSF-venous fistulas causing SIH was 80% (54% experiencing moderate-to-severe symptoms, 7.6% requiring therapeutic LP). Treatment of a single fistula and higher preprocedural opening pressures were associated with increased risk of more severe RIH and need for intervention.
