keep rows from the first file that do not match with second file

Question

I have 2 files, each has more than 1000 rows,

head file 1


3.3    6.6    10    0    0.6    0.33    "Ha1_00044004__C"
0      0       0   10     0       1     "Ha1_00043486__A"
3.3    6.6    10    0    0.6    0.3     "Ha1_00045379__C"
3      6       9    1    0.6    0.4     "Ha1_00045316__C"

head file 2
0    0    0    10    0    1     "Ha1_00043486__A"
0    0    0    10    0    1     "Ha1_00043840__A"
0    0    0    10    0    1     "Ha1_00043671__A"
0    0    0    10    0    1     "Ha1_00044403__A"
3.3    6.6    10    0    0.6    0.3     "Ha1_00045379__C"
3      6       9    1    0.6    0.4     "Ha1_00045316__C"

I want to keep only those rows from the file1 that the last column "does not" match with the last column of file2. I would appreciate any help.

my desired output

3.3    6.6    10    0    0.6    0.33    "Ha1_00044004__C"

Answer 1

You can create an associative array (or hash) keyed on the last fields of the first file, then check if the last field of the second file is NOT a valid key:

$ awk 'NR==FNR {a[$NF]++; next} !($NF in a)' file2 file1
3.3    6.6    10    0    0.6    0.33    "Ha1_00044004__C"

Answer 2

Try:

grep -vf <(awk '{print $7}' < file2) file1