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Numerous men have been taking Viagra for erectile dysfunction, and it was noted that Viagra does not only have an effect to a man’s sexual function, but it also has an effect on the heart. Effects of the hormonal stress to the human heart were noted to be decreased in men taking Viagra. The study, when tried on mice, was more noticeable as it had the tendency to avert and undo the harmful long-term effects of chronic hypertension on their heart.

Since Viagra has an effect to dilate genital blood vessels to maintain an erection, research was done if it has an effect on the human heart. And it was found out that it has potential benefits for the treatment of pulmonary hypertension. And this study was headed by the Johns Hopkins researchers. But before that, Viagra was never thought to have an effect on the heart.
Viagra works to dull the increased heart beat, which is a product of chemically-induced stress. It works to decrease the force needed to pump an excessive amount of blood from the heart to the body.

David Kass, M.D., a cardiologist and study senior author of Johns Hopkins study, and his researchers performed experiments on mice and noticed that Viagra is effective in blocking short-term consequences of hormonal stresses in the heart. Long-term damages of chronic hypertension on the heart is also prevented and reversed by Viagra. Negative effects of heart failure and cardiac hypertrophy on the weakened heart muscles in mouse experiments performed by David Kass, M.D. and his researchers are also reversed by Viagra, but this was not tested on human hearts yet so no solid evidence has been gathered to prove this.

To prove this, they conducted the Johns Hopkins study, and it showed that Viagra also has an effect in slowing heart rate after an injection of dobutamine. Thirty five men and women volunteered to go on the Johns Hopkins study for a period of six months. Necessary measurements of heart function like echocardiogram, electrocardiogram, and blood pressure readings were taken before and after the injection of dobutamine (dobutamine is a synthetic derivative of dopamine that increases heart rate and heart contraction). It showed increased heart rate and increased heart contraction by 150%. Then they were separated into two groups; those who took sildenafil (Viagra) and those who took sugar pill placebo. Dobutamine was again given to the individuals to see what sildenafil and sugar placebo has on the heart. It showed that the first group’s heart rate and heart contraction decreased by 50% while those from the second group increased yet again to about 150%.

The success of the Johns Hopkins study started other researchers on how sildenafil works when it comes to the immediate and long-term effects on the heart and other potential benefits they could get from sildenafil.

But these studies are not yet finished. For now, it is good to know that it inhibits the action of phosphodiesterase 5 or PDE5A from breaking down cyclic GMP, a key molecule that aids in the controlling of stress and hypertrophy of the heart.

You can get Generic Viagra viagra cialis online pharmacy pharmacy.

By: Jerry Black

Article Directory: http://www.articledashboard.com


This Knowledge will help improve your sexual life in many ways.

The NFL lockout has led to a number of arrests of players with nothing better to do but drive around turning up the bass on their car stereo systems to ear-splitting levels. Examples:

Louis Murphy of the Oakland Raiders was pulled over for playing his music too loud, then refused to show his ID, then arrested for resisting arrest. A search of his car revealed an unlabeled bottle of online pharmacy viagra pills; Murphy claimed he took the label off so that his girlfriend would not know what the pills were, which would have suggested that he required extra assistance to get excited by the idea of sleeping with her.

Jason Peters of the Philadelphia Eagles was charged with violating the Shreveport, Louisiana, loud music policy and resisting arrest. No other reason was given for the arrest.

The Raiders may not have been “bad” on the field lately, but they certainly are bad when it comes to music. Another one of the team’s players, Mario Henderson, was pulled over for—yes—playing his music too loud. He was subsequently arrested for having a gun in his car without a concealed weapons permit handy.

These haven’t been the only arrests, nor for reasons as high-handed, but they are suggestive of the fact that being a high-paid black athlete is nothing to local police save a grinning “I got you.” You think police are not on the look-out for black athletes driving expensive cars, trying to show them who is the real “boss?” Frankly, I can’t stand some of this music blasting out of some of these cars, but besides my feelings, there are other good reasons to turn that bass down.

Meanwhile, remember George Stephanopoulos? He used to be a “player” inside the Clinton administration; after that he became a talking head on television, and now has devolved into a high-paying position on Good Morning America, interviewing so-called “newsmakers” such as Jenn Sterger last week. I don’t know who has the time to watch this stuff, maybe desperate housewives and unemployed people who need a titillating diversion in their lives, but apparently Sterger is still playing the victim (although she admits that she and Brett Favre never actually “met”), claims that she never intended things to go this far (of course not—now that she’s been out of job since she was fired from Versus), and she still claims that she doesn’t know how Deadspin got those voicemails and pictures that she gigglingly confessed to having to that website’s editor (they were “fun to laugh at” betwixt friends). Now, of course, she’s mad that her former manager won’t return the “goods” that Bus Cook claimed were being used to “suggest” a money deal over (i.e. blackmail), and plans on writing a “tell-all” book on the case; she knows that any idea of having a “serious” career would be over.

I’ve talked about this issue many times. What Favre did or alleged to have done was stupid given the fact that he was married. But it also remains true that facts suggest that Sterger was an enthusiastic attention-seeker, using whatever “assets” she had. There she was at those Florida State football games, the very sight of her would convince 5,000 “red-blooded American males” to enroll at the school; there she was posing in Playboy. The next logical step in her career trajectory? Getting gig on Sports Illustrated’s website, supposedly to provide “atmosphere” posting about college life, like partying. It was reported in September, 2007 that she had been fired. In her predictable cat-claw way, Sterger denied the charge, although given the fact that she had not been given an assignment for several months prior (in fact, her output consisted of a couple of innocuous items over three months), SI was probably just being nice by firing her without telling her. Then she became a New York Jets “hostess”—not a “team reporter” as was initially claimed. One sports reporter who examined Sterger’s blog noted that all of the posts dating from the Jets period were deleted. I wonder why. Sterger managed to find employment on Versus’ “The Daily Line,” which was already in trouble a month in; if someone thought that Sterger’s connection with Favre would bring ratings, it backfired. In between times, Sterger has been looking for “reality” TV work, which is generally the last option for talentless, self-enamored people looking for fame and a quick buck.

The National Sports Daily reported “rumors” that Sterger was less interested in Favre (the “old man” who was “fun to laugh at”), but in Brady Quinn, who was drafted as the “quarterback of the future” by Cleveland, but who since has been keeping the bench warm for Tim Tebow in Denver. If the story is right, Sterger wanted to have an “adult” relationship, which to Quinn apparently meant “wifing” her-up and having kids (god, this is getting worse and worse). However, Sterger didn’t want to be perceived as a “trophy” wife (Sterger a “trophy wife?” How much worse can things get now?). “He never liked what I did for living,” Sterger supposedly wrote. Does she mean this Notre Dame boy didn’t like her selling her frame for fame? Of course not--she meant is her alleged acting and writing career, which frankly is as non-existent today as his football career. But that’s all over; the next time she saw him, there were no butterflies in her stomach; it didn’t matter because he didn’t notice her or say hello anyways. “I ignored him…all was right in the world.”

OK,OK, OK. You win.

Orgasm Inc. director Liz Canner.

The load down



By Ed Rampell



In the early 1960s Pres. Kennedy announced America would land a man on the moon by the decade’s end. Science’s current counterpart to the space race is the cum-petition to send women over the moon. That is to say, to create something that’s a gender equivalent to those drugs and treatments aimed at overcoming erectile dysfunction. This sex aid for women to achieve orgasms could take the form of a sort of female Viagra, or perhaps cream, shot, surgery or even electrodes invasively inserted into the spine. In any case, the race is on, and, as every salesman knows, sex sells, so there’s gold in them thar hills.



Director Liz Canner’s uncanny documentary may have started out as a cinematic rumination on female pleasure, but it ended up becoming an expose of Big Pharma. According to Canner, she was originally hired by a pharmaceutical firm to edit erotic videos that would be used during clinical trials of a cream intended -- with a little help from our pornographic friends -- to aid human female lab rats to attain orgasms.



However, the company that hired the cagey Canner -- who has a background of making human rights documentaries about subjects such as Nicaragua, LAPD and the L.A. riots -- got much more than they bargained. Like that health insurance industry whistleblower Wendell Potter, Canner grew increasingly disturbed by what she was in a unique position to witness, and the filmmaker went rogue.



The result is Orgasm Inc., a probing look at what could be called the “Female Sexual Dysfunction Pharmaceutical Surgical Complex” (FSDPSC). Pills, surgery and other treatments can be costly and contain health risks, so according to the doc, in order to overcome these objections Big Pharma, et al, concocted the myth that Female Sexual Dysfunction (FSD) is a “disease.” Not only that, but having identified a dire need, the FSDPSC is riding to the rescue with the cure to this ailment it has identified and propagandizes about.



However, there’s a fly in the ointment (literally and figuratively). Females happen to be different from males, and the solution (assuming, of course, that there’s even a problem to be solved to begin with) is not simply a feminine version of those boner pills exalted in those schmaltzy commercials advising men what to do if their erections last longer than four hours, etc. As Dr. Sigmund Freud asked: “What do women want?” That’s the $64,000 question or, in the quest to create a female cheap cialis, etc., probably more like a $64 billion question. Like braggadocio partners, so far these pills, etc., promise more than they deliver, and in a sense, this is the perfect film to open in L.A. on April Fools’ Day.



Canner provides a valuable service in her doc by exposing the fact that most of the public pitchmen and women for these various drugs, etc., aimed at inducing vaginal and clitoral orgasms are paid by the same industry they are ballyhooing. In addition, these TV therapists, scientists and the like do not disclose their financial ties to the firms manufacturing the products they’re appraising and praising. During the Iraq War it was exposed that a number of those retired officers, etc., pontificating in news media outlets were actually paid by the Pentagon, and even provided daily talking points to them. When it was exposed that pundit/ bandit Armstrong Williams was secretly taking money from the Bush Administration while pushing Bush educational policies and bashing those of opponents, Williams’ “defense” was that he didn’t know he was doing anything wrong.



Perpetrators of these covert conflicts of interest are worse than immoral, they’re amoral, absolutely lacking any sort of ethical compass. When Charles Ferguson confronts culprits of “say for pay” and insider trading in his Oscar winning Inside Job, the perps have cognitive dissonance, since they operate in a realm that’s so sleazy and corrupt they simply can’t recognize what’s right and wrong. (The legal definition of insanity, by the way.)



The corruption Canner cannily exposes in Orgasm Inc. makes a strong case that during this High Renaissance of Insider Trading and Conflicts of Interest we need a sort of truth in advertising law applied to pitchmen/women, requiring them to disclose their financial ties regarding what they’re pitching. Instead of being fobbed off as an independent expert, if some talking head (no pun intended) is taking money from a company whose products or goals he/she is endorsing, this should be disclosed to viewers/listeners/ readers, etc. So when some behind-the-scenes Pentagon goon poses as a disinterested commentator, but is really being paid off by a think tank funded by the defense industry, a label will identify him/her as such onscreen, etc. Let’s call a flack a flack -- and Canner does a great job doing just this. (BTW, in the interests of full disclosure I think that the United States of America should now be legally forced to change its name to the Incorporated States of America. I’m just saying…)



The worst abuse Canner exposes in Orgasm Inc. has to do with what’s called Designer Laser Vaginal Rejuvenation surgery. Much has been revealed about the dangers involved with “boob jobs," but this doc exposes plastic surgery on female private parts, to reduce the length of their vaginal lips and so on. (Maybe soon we’ll need labia labels?) In any case, the doc’s feminist spokespersons make a strong case that this is just a high tech version of the kind of female genital mutilation decried in “backwards” Third World nations. Holy clit!



Sexuality is a very powerful force, and our acceptance, sense of self-worth, being attractive, intimacy, need for physical and emotional satisfaction, and much mysteriously more, are wrapped up in it. Human beings are social animals; we’re not created through asexual reproduction. What Canner craftily shows is that the Female Sexual Dysfunction Pharmaceutical Surgical Complex preys upon women, exploits and heightens their insecurities and feelings of inadequacy, promising them pleasure, cum-panionship, approval, etc. All of which they, and their purveyors, stand to profiteer from -- whether they deliver the goods or -- like so many snake oil salesmen/women of the past -- don’t.



Canner’s technique (filmmaking, that is) is pretty conventional here. No Michael Moore-ian panache or cinematic style a la The Kid Stays in the Picture, that well-made 2002 doc about producer Robert Evans. She is also guilty of a certain amount of Puritanism when it comes to nudity. Like the pill pitchers she exposes, Canner knows full well that sex sells -- hence her doc’s catchy title, and its titillating, provocative ad depicting an apparently naked young blonde embracing a bottle of pills in between her spread thighs, head tossed back in what seems to be an orgasmic delight worthy of Meg Ryan in that famous When Harry Met Sally restaurant scene.



Yet there is no graphic nudity in Orgasm Inc. -- even when this could have greatly benefited viewers. For instance, when discussing vaginal plastic surgery, it would have been useful for audiences to actually see what’s being spoken about. Labia, vulva, etc., before and after operations. After all, film is a visual art form, not just talking heads (of which this doc is full of), and artists have fought valiantly for decades for the freedom to depict sexuality openly. It’s a mystery that, having legally won this free expression battle in America, so few of today’s (non-porn) filmmakers use that hard fought for liberty. The only genitalia to be seen onscreen in Orgasm Inc. comes in the form of pubic puppets (I kid thee not, Dear Reader). If there is sexual dysfunction en masse in America, it is precisely this unnatural attitude toward the human body, male and female, which results in puritanical perversity, obsessions and sexual repression. Alas, this otherwise insightful, inciting documentary may be somewhat guilty of perpetrating what it condemns.