Log inOpen app
Fifty Years
2,937 posts
user avatar
Fifty Years
@fiftyyears
Make something civilization needs. Helping great scientists and engineers become great entrepreneurs is our jam.
San Francisco, CA
substack.fiftyyears.com
Joined July 2016
85
Following
15.5K
Followers
user avatar
@fiftyyears

See Fifty Years’s full profile

Open X

New to X?

Sign up now to get your own personalized timeline!

Create account

By signing up, you agree to the Terms of Service and Privacy Policy, including Cookie Use.

Terms·Privacy·Cookies·Accessibility·Ads Info·© 2026 X Corp.
Don't miss what's happening
People on X are the first to know.
Log inSign up
  • Pinned
    user avatar
    Fifty Years
    @fiftyyears
    Oct 13, 2024
    Make something civilization needs.
    31
    55
    1.1K
    129K
  • Fifty Years reposted
    user avatar
    Alex Teng
    Fifty Years
    @alexteng101
    7h
    LETS DO BETTER! the Star Trek future arrives because we make it arrive! we're here to help fiftyyears.com/5050
    user avatar
    Seth Bannon
    Fifty Years
    @sethbannon
    8h
    We can do better. Instead of the next AI calendar optimizer: medicine designed for your genome. Cargo crossing oceans without emissions. Cities on other worlds. If you're a scientist or engineer who wants to build this future -- 5050 applications are open.
    00:00
    2
    1
    7
    981
  • Fifty Years reposted
    user avatar
    Martin Borch Jensen
    @MartinBJensen
    3h
    @fiftyyears is the @DanielLurie of VC: Just do all the things an ideal investor would do, instead of talking of doing the things.
    user avatar
    Seth Bannon
    Fifty Years
    @sethbannon
    5h
    Hundreds of deeptech VCs were asked: which two funds are most helpful to founders? @fiftyyears ranked in the top tier 🥹 No compliment means more to us than "helpful to founders." We'd take it over anything -- smart, great returns, even good looking.
    1
    2
    7
    907
  • Fifty Years reposted
    user avatar
    Derya Unutmaz, MD
    @DeryaTR_
    10h
    This is the way! Congratulations to @fiftyyears helping to make something civilization needs!
    user avatar
    Seth Bannon
    Fifty Years
    @sethbannon
    Jul 7
    Ten years ago, almost everyone told us the same thing: back companies solving humanity's biggest problems, and you'll have to accept lower returns. Today we sent our LPs a note announcing that Fifty Years Fund I has reached 7.5x DPI.
    2
    20
    6.4K
  • Fifty Years reposted
    user avatar
    Seth Bannon
    Fifty Years
    @sethbannon
    8h
    We can do better. Instead of the next AI calendar optimizer: medicine designed for your genome. Cargo crossing oceans without emissions. Cities on other worlds. If you're a scientist or engineer who wants to build this future -- 5050 applications are open.
    00:00
    7
    14
    72
    6.3K
  • Fifty Years reposted
    user avatar
    Alex Teng
    Fifty Years
    @alexteng101
    Jul 8
    SO EXCITED I can finally talk about Capable!
    user avatar
    Isaak
    @isaakfreeman
    Jul 8
    We built the lab that's able to go from AI-led drug design to data in 24h. GPT-8 won't be bottlenecked by intelligence. It needs a biological compute layer. This is Capable. We're turning AI capabilities into human capabilities--starting with short-sleeper peptides.
    GIF
    1
    2
    16
    1.7K
  • Fifty Years reposted
    user avatar
    Seth Bannon
    Fifty Years
    @sethbannon
    Jul 8
    The crazy headline is the 24 hour turnaround from AI design to in-vivo data. But everything that's gone into that is what makes Capable special. 132 interviews for one hire. A second orthogonal system to validate every surprising result. Bringing in external labs to check
    This post is unavailable.
    5
    6
    83
    20K
  • Fifty Years reposted
    user avatar
    Astranis Space Technologies
    @Astranis
    Jul 8
    Chunghwa Telecom and Astranis are building Taiwan's first dedicated satellite to deliver secure digital infrastructure for flexibility and resilience. The partnership will also provide a critical real-time backup against natural disasters, submarine cable disruptions, and
    00:00
    2
    16
    43
    3.1K
  • Fifty Years reposted
    user avatar
    Matt Loszak
    Aalo Atomics
    @MattLoszak
    Jul 8
    PS, our crack marketing team also updated the website this week and it might be the coolest thing I've ever seen. aalo.com
    00:00
    15
    26
    350
    75K
  • Fifty Years reposted
    user avatar
    Fifty Years
    @fiftyyears
    Jul 7
    Replying to @sethbannon
    Make something civilization needs.
    1
    1
    18
    844
  • Fifty Years reposted
    user avatar
    Isaak
    @isaakfreeman
    Jul 8
    I chose to partner with 50 Years because they deeply care about enabling humanity to flourish and making their founders the best versions of themselves. On every single step along the way they double and triple down. Couldn't recommend Seth & the team more.
    user avatar
    Seth Bannon
    Fifty Years
    @sethbannon
    Jul 8
    The crazy headline is the 24 hour turnaround from AI design to in-vivo data. But everything that's gone into that is what makes Capable special. 132 interviews for one hire. A second orthogonal system to validate every surprising result. Bringing in external labs to check
    2
    3
    57
    5.8K
  • Fifty Years reposted
    user avatar
    george church
    @geochurch
    Jul 8
    you should consider joining. Great team.
    user avatar
    Isaak
    @isaakfreeman
    Jul 8
    Replying to @isaakfreeman
    We're a vibrant and intensely mission-driven team in San Francisco from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We're grateful to be backed early with $12M by: - 50 Years & HOF - OpenAI executives Wojciech Zaremba, Kevin Weil, Srinivas Narayanan, and Fidji Simo
    3
    7
    89
    42K
  • Fifty Years reposted
    user avatar
    Isaak
    @isaakfreeman
    Jul 8
    We built the lab that's able to go from AI-led drug design to data in 24h. GPT-8 won't be bottlenecked by intelligence. It needs a biological compute layer. This is Capable. We're turning AI capabilities into human capabilities--starting with short-sleeper peptides.
    GIF
    109
    124
    1.3K
    464K
  • Fifty Years reposted
    user avatar
    Sumner L Norman
    Merge Labs
    @SumnerLN
    Jul 7
    Build things that matter. Period.
    user avatar
    Seth Bannon
    Fifty Years
    @sethbannon
    Jul 7
    Ten years ago, almost everyone told us the same thing: back companies solving humanity's biggest problems, and you'll have to accept lower returns. Today we sent our LPs a note announcing that Fifty Years Fund I has reached 7.5x DPI.
    3
    3
    28
    3.8K