Chaperone-mediated autophagy

Latest research

1. AKT (Ser473) suppression mediates ceritinib cardiotoxicity through autophagic flux impairment and mitochondrial injury

   • Feng Jiang
   • Huang-xi Fu
   • Zhi-fei Xu

   in Acta Pharmacologica Sinica

   Article 21 August 2026

   

2. DH-AUTAC induces ferroptosis in colorectal cancer by targeting DHODH for autophagic degradation through KCTD10–SQSTM1 signaling

   • Weibing Wang
   • Xigang Hu

   in Journal of Gastroenterology

   Article 20 August 2026

   

3. SRPK3 exacerbates cardiac ischemia/reperfusion injury by regulating KLF3-mTOR/P70 S6K-mediated autophagy

   • Yun Xing
   • Sai-yang Xie
   • Qi-zhu Tang

   in Acta Pharmacologica Sinica

   Article Open access 18 August 2026

   

4. Astrocytic LCN2 mediates pathological crosstalk with neurons to promote neuronal loss in sepsis-associated encephalopathy

   • Cuiping Guo
   • Yi Liu
   • Xiaochuan Wang

   in Cell Death & Differentiation

   Article 18 August 2026

   

5. A standards-based framework for medical image encryption using ChaCha20, HKDF, and integrated HMAC authentication

   • Osama Ouda

   in Journal of King Saud University Computer and Information Sciences

   Article Open access 14 August 2026

   

6. Inhibition of PINK1/Parkin-mediated mitophagy enhances the susceptibility of breast cancer to cuproptosis

   • Chaoyi Tang
   • Ka Su
   • Jiehua Li

   in Oncogene

   Article 13 August 2026

   

7. Chrysosplenetin-induced TMED3 aggregation triggers unfolded protein response in pancreatic cancer

   • Zhe Zhang
   • Ningna Weng
   • Qi Zhang

   in EMBO Molecular Medicine

   Article Open access 13 August 2026

   

8. Erjingwan Alleviates Parkinson’s Disease via Activation of PPARA-Mediated Autophagy

   • Shaopeng Cao
   • Yongmei Wu
   • Zhaoyang Qiu

   in Applied Biochemistry and Biotechnology

   Article 12 August 2026

   

9. Puerarin alleviates sciatic nerve injury in diabetic peripheral neuropathy rat via HSP90AA1

   • Nuo Shen
   • Lulin Zheng
   • Guoming Shen

   in 3 Biotech

   Article 11 August 2026

   

10. RNF5 promotes acute lung injury through HSPA5 ER-to-cytosol translocation and resultant PERK activation

    • Ya-Zhou Sun
    • Xin-Yan Li
    • Xiao-Jing Zhang

    in Cell Death & Differentiation

    Article 10 August 2026

    

11. Selenium Nanoparticles Alleviate Intestinal Epithelial Barrier Dysfunction by Coordinating Mitochondria-lysosome Communication under Dual Organelle Stress

    • Jiajing Chang
    • Xiaonan Zeng
    • Chunlan Xu

    in Biological Trace Element Research

    Article 10 August 2026

    

12. Inhibition of miR-106a/b Modulates Autophagy-Related Gene Expression in the ULK1–Beclin-1–ATG12 Axis in Experimental Colitis

    • Elif Ayça Şahi̇n
    • Süheyla Esra Özkoçer
    • Ece Konac

    in Bratislava Medical Journal

    Article 10 August 2026

    

13. PGAM1 rheostat in glycolysis and autophagy

    • Kay F. Macleod

    in Nature Cell Biology

    Article 07 August 2026

    

14. Intranasal Delivery of Berberine via QbD-Engineered Chitosan Coated Liposomes: Formulation Fabrication and Cellular Efficacy for Alzheimer’s Intervention

    • Mansi Negi
    • Vivek Phatale
    • Saurabh Srivastava

    in BioNanoScience

    Article 07 August 2026

    

15. FUNDC1-mediated mitochondrial quality control protects against immune checkpoint inhibitor–associated cardiac injury

    • Nengfeng Zhang
    • Yao Zhou
    • Haiyun Liu

    in Immunologic Research

    Article 06 August 2026

    

16. Yiqi Huoxue Jiedu formula protects against sepsis-associated lung injury by modulating macrophage mitophagy and mtDNA-STING signaling

    • Shuqi Ma
    • Qiusha Pan
    • Rui Chen

    in Chinese Medicine

    Article Open access 04 August 2026

    

17. Beyond the Pump: Unravelling Immunometabolic Crosstalk and Organelle Dynamics in Sepsis-Induced Cardiomyopathy

    • Guangfu Liu
    • Liya Hao
    • Zhenzhu Liu

    in Journal of Cardiovascular Translational Research

    Article 04 August 2026

    

18. Pharmacological evolution of natural product–based and chemically engineered autophagy-modulating strategies in neurodegenerative diseases: a bibliometric mapping analysis (2006–2025)

    • Menghao Liu
    • Shumin Ye

    in Naunyn-Schmiedeberg's Archives of Pharmacology

    Article 03 August 2026

    

19. Recombinant humanized collagen type Ⅲ-modified rapamycin liposomes for promoting osteoarthritis repair

    • Chenxin Liu
    • Wenling Dai
    • Xingdong Zhang

    in Collagen and Leather

    Article Open access 02 August 2026

    

20. The glycolytic enzyme PGAM1 functions as a metabolic–autophagy checkpoint to coordinate growth and stress tolerance

    • Yi Zhang
    • Pengwei Zhao
    • Cong Yi

    in Nature Cell Biology

    Article 29 July 2026