BoltzGen: Toward Universal Binder Design
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Updated
May 1, 2026 - Jupyter Notebook
BoltzGen: Toward Universal Binder Design
Propose CDR single-point mutations that rescue antibody expression without disrupting antigen binding, using bound vs. unbound ProteinMPNN logit analysis.
Benchmarking antibody-specific PLMs vs. BLOSUM62 for variant fitness prediction on combinatorial CDR-H3 libraries
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