FlyBase Allele Report: Mmus\Pelo[UASp.cYa]

General Information

Symbol

Mmus\Pelo^UASp.cYa

Species

M. musculus

Name

FlyBase ID

FBal0324971

Feature type

allele

Associated gene

Mmus\Pelo

Associated Insertion(s)

Carried in Construct

P{UASp-mPelo.Y}

Transgenic product class

cDNA

(Yang et al., 2015)

wild_type

(Yang et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Yang et al., 2015)

wild_type

(Yang et al., 2015)

Mutagen

in vitro construct

(Yang et al., 2015)

Progenitor genotype

Carried in construct

P{UASp-mPelo.Y}

Cytology

Description

UASp regulatory sequences drive expression of Mmus\Pelo cDNA.

(Yang et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

UASp

binary expression system - regulatory region

Encoded product / tool

Mmus\Pelo

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Mmus\Pelo^UASp.cYa/Scer\GAL4^αTub84B.PL is a suppressor of male sterile phenotype of pelo¹/pelo^PB60

(Yang et al., 2015)

NOT Suppressor of

Statement

Reference

Mmus\Pelo^UASp.cYa/Scer\GAL4^{VP16.nanos.UTR} is a non-suppressor of male sterile phenotype of pelo¹/pelo^PB60

(Yang et al., 2015)

Phenotype Manifest In

Suppressor of

Statement

Reference

Mmus\Pelo^UASp.cYa/Scer\GAL4^αTub84B.PL is a suppressor | partially of testis phenotype of pelo¹/pelo^PB60

(Yang et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

The spermatogenesis defects but not male sterility characteristic for pelo¹/pelo^PB60 transheterozygous flies can be partially rescued by expression of Mmus\Pelo^{Scer\UAS.P\T.cYa} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} while the Scer\GAL4^αTub84B.PL-driven expression restores male fertility to near wild-type level.

(Yang et al., 2015)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Mmus\Pelo^{Scer\UAS.P\T.cYa}

Mmus\Pelo^UASp.cYa

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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