FlyBase Allele Report: Bant\EF[UAS.cGa]

General Information

Symbol

Bant\EF^UAS.cGa

Species

B. anthracis

Name

FlyBase ID

FBal0321163

Feature type

allele

Associated gene

Bant\EF

Associated Insertion(s)

Carried in Construct

P{UAS-EF.G}

Also Known As

UAS-EF

Transgenic product class

wild_type

(Guichard et al., 2006)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Guichard et al., 2006)

Mutagen

in vitro construct

(Guichard et al., 2006)

Progenitor genotype

Carried in construct

P{UAS-EF.G}

Cytology

Description

UAS regulatory sequences drive expression of Bant\EF coding sequences.

(Guichard et al., 2006)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Bant\EF

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal, with Scer\GAL4^ap-md544

(Guichard et al., 2006)

lethal, with Scer\GAL4^dpp.blk1

(Guichard et al., 2006)

lethal, with Scer\GAL4^ptc-559.1

(Guichard et al., 2006)

viable | temperature conditional, with Scer\GAL4^dpp.blk1

(Guichard et al., 2006)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Guichard et al., 2006)

eye, with Scer\GAL4^GMR.PF

(Guichard et al., 2006)

wing, with Scer\GAL4^71B

(Guichard et al., 2006)

wing, with Scer\GAL4^bs-1348

(Guichard et al., 2010, Guichard et al., 2006)

wing, with Scer\GAL4^Bx-MS1096

(Guichard et al., 2010, Guichard et al., 2006)

wing, with Scer\GAL4^sca-109-68

(Guichard et al., 2006)

wing, with Scer\GAL4^vg.PM

(Guichard et al., 2006)

wing cell | temperature conditional, with Scer\GAL4^dpp.blk1

(Guichard et al., 2006)

wing vein, with Scer\GAL4^bs-1348

(Guichard et al., 2010)

wing vein, with Scer\GAL4^Bx-MS1096

(Guichard et al., 2010)

wing vein L3 | temperature conditional, with Scer\GAL4^dpp.blk1

(Guichard et al., 2006)

Detailed Description

Statement

Reference

Expression of Zzzz\EF^Scer\UAS.cGa in the wing disc primordium under the control of Scer\GAL4^bs-1348 results in mild occasional notching of the wing margin and small wings with altered vein spacing.

Expression of Zzzz\EF^Scer\UAS.cGa in the wing disc primordium under the control of Scer\GAL4^Bx-MS1096 results in mild occasional notching of the wing margin and small wings with altered vein spacing.

(Guichard et al., 2010)

Expression of Zzzz\EF^Scer\UAS.cGa under the control of Scer\GAL4^ap-md544, Scer\GAL4^ptc-559.1, or Scer\GAL4^dpp.blk1 at 25[o]C results in lethality.

Expression of Zzzz\EF^Scer\UAS.cGa under the control of Scer\GAL4^71B, Scer\GAL4^bs-1348, Scer\GAL4^sca-109-68, Scer\GAL4^Bx-MS1096 or Scer\GAL4^vg.PM results in strong composite wing phenotypes.

Expression of Zzzz\EF^Scer\UAS.cGa under the control of Scer\GAL4^ey.PH or Scer\GAL4^GMR.PF results in small or rough eyes.

Expression of Zzzz\EF^Scer\UAS.cGa under the control of Scer\GAL4^dpp.blk1 at 29[o]C, unlike many other drivers, produces viable adult flies. However, these flies have a reduced spacing between the L3 and L4 veins and occasional truncations of the L3 vein.

Expression of Zzzz\EF^Scer\UAS.cGa under the control of Scer\GAL4^dpp.blk1 does not cause a detectable phenotype in the leg, and only a moderate hh-like phenotype in the wing.

(Guichard et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^dpp.blk1/Bant\EF^UAS.cGa is a suppressor of lethal | pharate adult stage phenotype of Pka-R1^BDK.UAS

(Guichard et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Bant\EF^UAS.cGa, Scer\GAL4^bs-1348 has wing phenotype, enhanceable by Rab11^{S25N.UASp.YFP}/Scer\GAL4^Bx-MS1096

(Guichard et al., 2010)

Bant\EF^UAS.cGa has wing vein L3 | temperature conditional phenotype, enhanceable by hh^unspecified/Scer\GAL4^dpp.blk1

(Guichard et al., 2006)

Bant\EF^UAS.cGa has wing cell | temperature conditional phenotype, enhanceable by hh^unspecified/Scer\GAL4^dpp.blk1

(Guichard et al., 2006)

Suppressed by

Statement

Reference

Bant\EF^UAS.cGa, Scer\GAL4^Bx-MS1096 has wing phenotype, suppressible by Rab11^UAS.EGFP, Scer\GAL4^Bx-MS1096

(Guichard et al., 2010)

Suppressor of

Statement

Reference

Scer\GAL4^dpp.blk1/Bant\EF^UAS.cGa is a suppressor of wing phenotype of Pka-R1^BDK.UAS

(Guichard et al., 2006)

Scer\GAL4^dpp.blk1/Bant\EF^UAS.cGa is a suppressor of leg phenotype of Pka-R1^BDK.UAS

(Guichard et al., 2006)

Other

Statement

Reference

Bant\EF^UAS.cGa, Bant\lef^UAS.cGa, Scer\GAL4^bs-1348 has wing margin phenotype

(Guichard et al., 2010)

Bant\EF^UAS.cGa, Bant\lef^UAS.cGa, Scer\GAL4^Bx-MS1096 has wing margin phenotype

(Guichard et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Co-expression of Zzzz\EF^Scer\UAS.cGa and Zzzz\lef^Scer\UAS.cGa in the wing disc primordium under the control of Scer\GAL4^bs-1348 produces a strong and penetrant wing margin notching phenotype.

Co-expression of Zzzz\EF^Scer\UAS.cGa and Zzzz\lef^Scer\UAS.cGa in the wing disc primordium under the control of Scer\GAL4^Bx-MS1096 produces a strong and penetrant wing margin notching phenotype.

Expression of Rab11^{S25N.Scer\UAS.P\T.T:Avic\GFP-YFP} in the wing disc primordium enhances the activity of Zzzz\EF^Scer\UAS.cGa (when both are under the control of Scer\GAL4^Bx-MS1096).

Expression of Rab11^{Scer\UAS.T:Avic\GFP-EGFP} in the wing disc primordium suppresses the activity of Zzzz\EF^Scer\UAS.cGa (when both are under the control of Scer\GAL4^Bx-MS1096).

(Guichard et al., 2010)

Expression of Zzzz\EF^Scer\UAS.cGa under the control of Scer\GAL4^dpp.blk1 in a hh^unspecified background significantly enhances the Zzzz\EF^Scer\UAS.cGa phenotype.

(Guichard et al., 2006)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Bant\EF^Scer\UAS.cGa

Bant\EF^UAS.cGa

Zzzz\EF^Scer\UAS.cGa

Name Synonyms

Secondary FlyBase IDs

FBal0320549
FBal0247341

References (4)

Report Sections

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