FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ineRB.UAS.cLa
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General Information
Symbol
Dmel\ineRB.UAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Luan
FlyBase ID
FBal0302488
Feature type
allele
Associated gene
Dmel\ine
Associated Insertion(s)
Carried in Construct
P{UAS-ine.RB.L}
Key Links
Transgenic product class
wild_type
(Luan et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Luan et al., 2015)
Mutagen
in vitro construct
(Luan et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-ine.RB.L}
Cytology
Description

UASt regulatory sequences drive expression of the RB isoform of ine.

(Luan et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ine
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ineRB.UAS.cLa/Scer\GAL4Irk2.PL rescues ine2

      (Luan et al., 2015)

      ineRB.UAS.cLa/Scer\GAL4Irk2.PL rescues ine3

      (Luan et al., 2015)
      Fails to rescue

      ineRB.UAS.cLa/Scer\GAL4elav.PU fails to rescue ine2

      (Luan et al., 2015)

      ineRB.UAS.cLa/Scer\GAL4repo.PU fails to rescue ine2

      (Luan et al., 2015)

      ineRB.UAS.cLa/Scer\GAL4elav.PU fails to rescue ine3

      (Luan et al., 2015)

      ineRB.UAS.cLa/Scer\GAL4repo.PU fails to rescue ine3

      (Luan et al., 2015)
      Comments

      Expression of ineRB.Scer\UAS in the hindgut under the control of Scer\GAL4Irk2.PL rescues the lethality seen when ine2 mutant flies are raised on hypertonic medium. Expressing ineRB.Scer\UAS in neurons (Scer\GAL4elav.PU) or glia (Scer\GAL4repo.PU) does not rescue the lethality.

      Expression of ineRB.Scer\UAS in the hindgut under the control of Scer\GAL4Irk2.PL rescues the lethality seen when ine3 mutant flies are raised on hypertonic medium. Expressing ineRB.Scer\UAS in neurons (Scer\GAL4elav.PU) or glia (Scer\GAL4repo.PU) does not rescue the lethality.

      Expression of ineRB.Scer\UAS in the hindgut under the control of Scer\GAL4Irk2.PL rescues the increased sensitivity to lack of water seen when ine2 mutant flies. Expressing ineRB.Scer\UAS in neurons (Scer\GAL4elav.PU) or glia (Scer\GAL4repo.PU) does not rescue this increased sensitivity.

      (Luan et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ineRB.Scer\UAS.cLa
      ineRB.UAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Luan
      Secondary FlyBase IDs
        References (1)