FlyBase Allele Report: Dmel\Rps6kc1[HMJ22016]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Rps6kc1^HMJ22016

General Information

Symbol

Dmel\Rps6kc1^HMJ22016

Species

D. melanogaster

Name

FlyBase ID

FBal0300503

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ22016}

Key Links

Genomic Maps

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMJ22016}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^da.G32

(Planas-Serra et al., 2025)

decreased rate of adult locomotory behavior, with Scer\GAL4^da.G32

(Planas-Serra et al., 2025)

decreased rate of adult locomotory behavior, with Scer\GAL4^elav.PU

(Planas-Serra et al., 2025)

decreased size, with Scer\GAL4^da.G32

(Planas-Serra et al., 2025)

short lived, with Scer\GAL4^da.G32

(Planas-Serra et al., 2025)

short lived, with Scer\GAL4^elav.PU

(Planas-Serra et al., 2025)

Phenotype Manifest In

indirect flight muscle, with Scer\GAL4^da.G32

(Planas-Serra et al., 2025)

NMJ bouton, with Scer\GAL4^da.G32

(Planas-Serra et al., 2025)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Rps6kc1^HMJ22016, Scer\GAL4^elav.PU has decreased rate of adult locomotory behavior phenotype, enhanceable by mTor^HMS00904, Scer\GAL4^elav.PU

(Planas-Serra et al., 2025)

Suppressed by

Statement

Reference

Rps6kc1^HMJ22016, Scer\GAL4^elav.PU has decreased rate of adult locomotory behavior phenotype, suppressible | partially by mTor^UAS.Tag:MYC, Scer\GAL4^elav.PU

(Planas-Serra et al., 2025)

Rps6kc1^HMJ22016, Scer\GAL4^elav.PU has short lived phenotype, suppressible | partially by mTor^UAS.Tag:MYC, Scer\GAL4^elav.PU

(Planas-Serra et al., 2025)

Other

Statement

Reference

Rps6kc1^HMJ22016, Scer\GAL4^elav.PU, mTor^HMS00904 has short lived phenotype

(Planas-Serra et al., 2025)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

58101

y¹ v¹; P{TRiP.HMJ22016}attP40

HMJ22016

y¹ v¹; P{TRiP.HMJ22016}attP40/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG7156^HMJ22016

Rps6kc1^HMJ22016

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections