FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\vitoUAS.cMa
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General Information
Symbol
Dmel\vitoUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Marinho
FlyBase ID
FBal0256649
Feature type
allele
Associated gene
Dmel\vito
Associated Insertion(s)
Carried in Construct
P{UAS-vito.M}
Key Links
Transgenic product class
cDNA
(Marinho et al., 2011)
wild_type
(Marinho et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Marinho et al., 2011)
wild_type
(Marinho et al., 2011)
Mutagen
in vitro construct
(Marinho et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-vito.M}
Cytology
Description

UASt drives expression of the full-length vito LD10447 cDNA clone.

(Marinho et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
vito
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4ptc-559.1-mediated expression of vitoGD10890 results in reduced larval salivary gland growth. The nucleoli show a dramatic reorganization into two distinct regions: a peripheral and highly compact region with very smooth borders that surround internal vacuole-like structures. Salivary gland cells are significantly smaller than controls owing to a reduction in cytoplasmic volume and decrease in nuclear size.

      (Marinho et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      vitoUAS.cMa/Scer\GAL4ey.PU rescues vitoGD10890

      (Marinho et al., 2011)
      Comments

      Co-expression of vitoScer\UAS.cMa in the vitoGD10890, Scer\GAL4ey.PU background significantly rescues eye disc size, adult eye size and morphology, and several other cellular parameters.

      (Marinho et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      vitoScer\UAS.cMa
      vitoUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Marinho
      Secondary FlyBase IDs
        References (1)