FlyBase Allele Report: Dmel\aos[GMR.PC]

General Information

Symbol

Dmel\aos^GMR.PC

Species

D. melanogaster

Name

glass multimer reporter construct of Casci

FlyBase ID

FBal0097068

Feature type

allele

Associated gene

Dmel\aos

Associated Insertion(s)

Carried in Construct

P{GMR-argos.C}

Also Known As

GMR-argos

Key Links

Transgenic product class

wild_type

(Casci et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Casci et al., 1999)

Mutagen

in vitro construct

(Casci et al., 1999)

Progenitor genotype

Carried in construct

P{GMR-argos.C}

Cytology

Description

aos is expressed under the control of GMR regulatory sequences.

(Casci et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

aos

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Arya and Lakhotia, 2008, Tran et al., 2008, Casci et al., 1999)

Phenotype Manifest In

eye

(Mao and Freeman, 2009, Arya and Lakhotia, 2008, Tran et al., 2008, Casci et al., 1999)

interommatidial bristle

(Charroux et al., 2006)

ommatidium

(Arya and Lakhotia, 2008, Charroux et al., 2006)

Detailed Description

Statement

Reference

argos^GMR.PC flies display a rough-eye phenotype.

(Mao and Freeman, 2009)

aos^GMR.PC flies have reduced eyes with irregularly arranged ommatidia.

argos^GMR.PC flies have reduced eyes with irregularly arranged ommatidia.

(Arya and Lakhotia, 2008)

argos^GMR.PC flies have a rough eye phenotype.

(Tran et al., 2008)

Flies expressing one copy of argos^GMR.PC have a rough eye phenotype.

(Charroux et al., 2006)

Flies expressing argos^GMR.PC have a rough eye phenotype.

(Casci et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

aos^GMR.PC has visible phenotype, suppressible by Hsp60D^RNAi.Sym.UAS/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

aos^GMR.PC has visible phenotype, suppressible by sty[+]/sty^S73

(Casci et al., 1999)

aos^GMR.PC has visible phenotype, suppressible by sty[+]/sty^S88

(Casci et al., 1999)

NOT suppressed by

Statement

Reference

aos^GMR.PC has visible phenotype, non-suppressible by trbd^Delta/trbd[+]

(Tran et al., 2008)

Phenotype Manifest In

Enhanced by

Statement

Reference

aos^GMR.PC has interommatidial bristle phenotype, enhanceable by Gug^UAS.cCa/Scer\GAL4^GMR.PF

(Charroux et al., 2006)

aos^GMR.PC has ommatidium phenotype, enhanceable by Gug^UAS.cCa/Scer\GAL4^GMR.PF

(Charroux et al., 2006)

Suppressed by

Statement

Reference

aos^GMR.PC has eye phenotype, suppressible by Fas2[+]/Fas2^G0293

(Mao and Freeman, 2009)

aos^GMR.PC has eye phenotype, suppressible by Hsp60D^RNAi.Sym.UAS/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

aos^GMR.PC has ommatidium phenotype, suppressible by Hsp60D^RNAi.Sym.UAS/Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

aos^GMR.PC has interommatidial bristle phenotype, suppressible by Gug³⁵/Gug[+]

(Charroux et al., 2006)

aos^GMR.PC has ommatidium phenotype, suppressible by Gug³⁵/Gug[+]

(Charroux et al., 2006)

aos^GMR.PC has interommatidial bristle phenotype, suppressible by Gug¹⁴⁹⁶⁷

(Charroux et al., 2006)

aos^GMR.PC has ommatidium phenotype, suppressible by Gug¹⁴⁹⁶⁷

(Charroux et al., 2006)

aos^GMR.PC has eye phenotype, suppressible by sty[+]/sty^S73

(Casci et al., 1999)

aos^GMR.PC has eye phenotype, suppressible by sty[+]/sty^S88

(Casci et al., 1999)

NOT suppressed by

Statement

Reference

aos^GMR.PC has eye phenotype, non-suppressible by trbd^Delta/trbd[+]

(Tran et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

argos^GMR.PC rough eye phenotype is suppressed in the presence of Fas2^G0293/+.

(Mao and Freeman, 2009)

Co-expression of Hsp60D^{dsRNA.Sym.Scer\UAS} under the control of Scer\GAL4^GMR.PF suppresses the eye phenotype caused by aos^GMR.PC.

(Arya and Lakhotia, 2008)

The rough eye phenotype caused by argos^GMR.PC is not suppressed by trbd^Delta/+.

(Tran et al., 2008)

The rough eye phenotype seen when flies express one copy of argos^GMR.PC is substantially suppressed when these flies are heterozygous for Gug³⁵, and partially suppressed in Gug¹⁴⁹⁶⁷ heterozygotes.

Expression of Gug^Scer\UAS.cCa, under the control of Scer\GAL4^GMR.PF, enhances the rough eye phenotype seen in flies that express argos^GMR.PC.

(Charroux et al., 2006)

Null alleles of ru interact dominantly with argos^GMR.PC.

(Wasserman et al., 2000)

The argos^GMR.PC rough eye phenotype is dominantly suppressed by sty^S73 or sty^S88.

(Casci et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

aos^GMR.PC

argos^GMR.PC

Name Synonyms

glass multimer reporter construct of Casci

(Casci et al., 1999)

Secondary FlyBase IDs

References (8)

Report Sections

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