FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pwnunspecified
Open Close
General Information
Symbol
Dmel\pwnunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0060922
Feature type
allele
Associated gene
Dmel\pwn
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Somatic clones of pwnunspecified homozygous cells in the abdomen have normal planar polarity.

        (Lawrence et al., 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressed by
        Statement
        Reference

        pwnunspecified, stanE59 has trichome & adult abdomen | somatic clone | cell non-autonomous phenotype, suppressible | somatic clone by fzUAS.cSa/Scer\GAL4αTub84B.PL

        (Lawrence et al., 2004)
        Enhancer of
        Statement
        Reference

        pwnunspecified is an enhancer of trichome & adult abdomen phenotype of Vangstbm-6

        (Lawrence et al., 2004)
        Other
        Statement
        Reference

        pwnunspecified, stanE59 has trichome & adult abdomen | somatic clone phenotype

        (Lawrence et al., 2004)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The loss of polarity seen in Vangstbm-6 somatic clones in the adult abdomen is enhanced by pwnunspecified.

        In wings largely made up of pwnunspecified stanE59 homozygous somatic clones, the remaining heterozygous cells have normal polarity. pwnunspecified stanE59 homozygous somatic clones in the abdomen have a disheveled planar polarity phenotype. These clones occasionally cause non-autonomous effects on planar polarity just outside and usually anterior to the clone. This limited non-autonomous phenotype is suppressed if the clones are also fzScer\UAS.cSa; Scer\GAL4αTub84B.PL (produced by Scer\GAL80αTub84B.PL MARCM method).

        (Lawrence et al., 2004)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        The frequency of pwnunspecified clones produced by mitotic recombination during larval growth is greater in flies derived from crosses of pwnunspecified D.melanogaster females to D.melanogaster males than in flies derived from crosses of pwnunspecified D.melanogaster females to D.simulans males.

        (Sanchez et al., 1994)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        pwn
        (Lawrence et al., 2004)
        pwnunspecified
        unspecified
        (Sanchez et al., 1994)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)