FlyBase Allele Report: Dmel\ci[Zn:C.UAS]

General Information

Symbol

Dmel\ci^Zn:C.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0057690

Feature type

allele

Associated gene

Dmel\ci

Associated Insertion(s)

Carried in Construct

P{UAS-ciZn/C}

Also Known As

UAS-ciZn/C

Key Links

Transgenic product class

inframe_deletion

(Hepker et al., 1997)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Hepker et al., 1997)

Mutagen

in vitro construct

(Hepker et al., 1997)

Progenitor genotype

ci^UAS.cHb

(Hepker et al., 1997)

Carried in construct

P{UAS-ciZn/C}

Cytology

Description

Deletion of N-terminal ci coding region up to amino acid 440. Expression is governed by UASt regulatory sequences.

(Hepker et al., 1997)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^c591

(Amin et al., 1999)

Phenotype Manifest In

dorsal tracheal branch primordium, with Scer\GAL4^btl.PS

(Kato et al., 2004)

glial cell & eye disc | somatic clone, with Scer\GAL4^Act5C.PP

(Rangarajan et al., 2001)

ocellus, with Scer\GAL4^c591

(Amin et al., 1999)

tracheal tip cell | embryonic stage, with Scer\GAL4^btl.PS

(Kato et al., 2004)

ventral denticle belt, with Scer\GAL4^en-e16E

(Hepker et al., 1997)

Detailed Description

Statement

Reference

Dorsal tracheal branches in ci^{Zn:C.Scer\UAS}; Scer\GAL4^btl.PS embryos migrate aberrantly. The terminal cells of these branches produce multiple cytoplasmic extensions per cell instead of the single extensions seen in wild-type and, also unlike wild-type, these extensions are not confined to the posterior compartment.

(Kato et al., 2004)

When clones of ci^{Zn:C.Scer\UAS} are made in the developing eye (under the control of Scer\GAL4^Act5C.PP) glial cells are seen to overshoot anteriorly in the eye disc, past the axonal boundary.

(Rangarajan et al., 2001)

When driven by Scer\GAL4^c591 ocelli size is increased. This phenotype is stronger than that seen when ci^Scer\UAS.cHb is expressed under the control of Scer\GAL4^c591.

(Amin et al., 1999)

When expression is driven by Scer\GAL4^en-e16E, cuticles of embryos are relatively normal, though the denticles appear to have fewer denticles. When expression is driven by Scer\GAL4^ptc-559.1, cuticles of embryos are near normal.

(Hepker et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

Scer\GAL4^Act5C.PP, ci^Zn:C.UAS, eya^unspecified has glial cell & eye phenotype

(Rangarajan et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

When clones of ci^{Zn:C.Scer\UAS} (under the control of Scer\GAL4^Act5C.PP) are made in the developing eye in a eya^unspecified background, glial cells never enter the eye disc.

(Rangarajan et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

ci^{Zn/C.Scer\UAS}

ci^Zn/C.UAS

ci^{Zn:C.Scer\UAS}

ci^Zn:C.UAS

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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