Wikipedia

Geodin

Geodin is an antibiotic against Gram-positive bacteria with the molecular formula C17H8Cl2O7.[1][2] Geodin is produced by the fungus Aspergillus terreus.[3][4]

Geodin
Names
IUPAC name
Methyl (2R)-5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate[1]
Other names
  • Estin
  • Erdin methyl ester
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
UNII
  • InChI=1S/C17H12Cl2O7/c1-6-11(18)13(21)10-14(12(6)19)26-17(15(10)22)8(16(23)25-3)4-7(20)5-9(17)24-2/h4-5,21H,1-3H3/t17-/m1/s1
    Key: LUBKKVGXMXTXOZ-QGZVFWFLSA-N
  • CC1=C(C(=C2C(=C1Cl)O[C@]3(C2=O)C(=CC(=O)C=C3OC)C(=O)OC)O)Cl
Properties
C17H12Cl2O7
Molar mass 399.18 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

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  1. 1 2 "Geodin". Pubchem.ncbi.NLM.nih.gov.
  2. ↑ Korzybski, Tadeusz; Kowszyk-Gindifer, Zuzanna; Kurylowicz, Wlodzimierz (3 September 2013). Antibiotics: Origin, Nature and Properties. Elsevier. p. 1291. ISBN 978-1-4832-2304-9.
  3. ↑ Rønnest, Mads H.; Nielsen, Morten T.; Leber, Blanka; Mortensen, Uffe H.; Krämer, Alwin; Clausen, Mads H.; Larsen, Thomas O.; Harris, Pernille (15 March 2011). "(+)-Geodin from Aspergillus terreus". Acta Crystallographica Section C Crystal Structure Communications. 67 (3): o125–o128. Bibcode:2011AcCrC..67O.125R. doi:10.1107/S0108270111005816. PMID 21368412.
  4. ↑ Gottlieb, David; Shaw, Paul D. (14 December 2013). Biosynthesis. Springer. p. 96. ISBN 978-3-662-38441-1.

Further reading

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  • Vaidyanathan, Seetharaman; Harrigan, George G.; Goodacre, Royston (20 March 2006). Metabolome Analyses:: Strategies for Systems Biology. Springer Science & Business Media. p. 377. ISBN 978-0-387-25240-7.
  • Comprehensive Natural Products III. Elsevier. 22 July 2020. p. 299. ISBN 978-0-08-102691-5.


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