Aleph-6, or ALEPH-6, also known as 4-phenylthio-2,5-dimethoxyamphetamine, is a psychedelic drug of the phenethylamine, amphetamine, and DOx families.[1][2][3] It is one of the Aleph series of compounds.[1][2][3]
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| Other names | ALEPH-6; DOT-6; 4-Phenylthio-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-4-phenylthioamphetamine; 4-PhS-DMA |
| Routes of administration | Oral[1] |
| Drug class | Serotonergic psychedelic; Hallucinogen |
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| Pharmacokinetic data | |
| Duration of action | "Probably long" (at least 12 hours)[1] |
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| Formula | C17H21NO2S |
| Molar mass | 303.42 g·mol−1 |
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In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists Aleph-6's dose as greater than 40 mg orally and its duration as "probably long".[1][2][3] The effects of Aleph-6 have been reported to include "un-worldliness", among others.[1] It was reported to have synergized with LSD when taken in combination with it.[1] Overall however, Shulgin regarded Aleph-6 as a "disappointment" and that it may be a "forever threshold thing".[1]
The chemical synthesis of Aleph-6 has been described.[1][2] The 2C analogue, 2C-T-6, has never been synthesized.[1]
Aleph-6 was first described in the literature by Shulgin in PiHKAL in 1991.[1][2][3] It is a controlled substance in Canada under phenethylamine blanket-ban language.[4]
See also
editReferences
edit- 1 2 3 4 5 6 7 8 9 10 11 Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. https://erowid.org/library/books_online/pihkal/pihkal006.shtml
- 1 2 3 4 5 Shulgin A, Manning T, Daley P (2011). The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley: Transform Press. ISBN 978-0-9630096-3-0.
- 1 2 3 4 Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived from the original on 13 July 2025.
- ↑ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.