Benefits of Nanocurcumin on Mortality in Patients with COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
et al., Journal of Integrative and Complementary Medicine, doi:10.1177/27683605251379004, Sep 2025
Curcumin for COVID-19
16th treatment shown to reduce risk in
February 2021, now with p = 0.0000000061 from 28 studies.
No treatment is 100% effective. Protocols
combine treatments.
6,600+ studies for
220+ treatments. c19early.org
|
Systematic review and meta-analysis of six RCTs showing significantly lower COVID-19 mortality with nanocurcumin treatment.
6 meta-analyses show significant improvements with curcumin for mortality1-6,
mechanical ventilation6,
hospitalization1,4,
recovery3,6,
progression6, and
symptoms1.
Currently there are 28 curcumin for COVID-19 studies, showing 63% lower mortality [36‑78%], 80% lower ventilation [25‑95%], 78% lower ICU admission [-27‑96%], and 27% lower hospitalization [18‑34%].
|
risk of death, 53.0% lower, RR 0.47, p = 0.02.
|
| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
1.
Vahedian-Azimi et al., Effectiveness of Curcumin on Outcomes of Hospitalized COVID-19 Patients: A Systematic Review of Clinical Trials, Nutrients, doi:10.3390/nu14020256.
2.
Kow et al., The effect of curcumin on the risk of mortality in patients with COVID-19: A systematic review and meta-analysis of randomized trials, Phytotherapy Research, doi:10.1002/ptr.7468.
3.
Shafiee et al., Curcumin for the treatment of COVID-19 patients: A meta-analysis of randomized controlled trials, Phytotherapy Research, doi:10.1002/ptr.7724.
4.
Shojaei et al., The effectiveness of nano‐curcumin on patients with COVID‐19: A systematic review of clinical trials, Phytotherapy Research, doi:10.1002/ptr.7778.
Shang et al., 16 Sep 2025, peer-reviewed, 3 authors.
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