Antiandrogens for the treatment of COVID‐19 patients: A meta‐analysis of randomized controlled trials

Cheema et al., Journal of Medical Virology, doi:10.1002/jmv.28740, Apr 2023
Mortality 63% improvement lower risk ← → higher risk Antiandrogens  Cheema et al.  META ANALYSIS c19early.org Cheema et al., J. Medical Virology, Apr 2023 0 0.5 1 1.5 2+ RR
7th treatment shown to reduce risk in September 2020, now with p = 0.000000056 from 49 studies.
No treatment is 100% effective. Protocols combine treatments.
6,600+ studies for 220+ treatments. c19early.org
Meta analysis of 14 antiandrogen RCTs for COVID-19, showing significantly lower mortality with treatment.
2 meta-analyses show significant improvements with antiandrogens for mortality1,2, hospitalization2, recovery2, and progression1.
Currently there are 49 antiandrogens for COVID-19 studies, showing 37% lower mortality [21‑50%], 47% lower ventilation [23‑64%], 36% lower ICU admission [5‑57%], 32% lower hospitalization [11‑48%], and 8% fewer cases [1‑14%].
risk of death, 63.0% lower, RR 0.37, p < 0.001.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Cheema et al., 18 Apr 2023, peer-reviewed, 9 authors.
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