Regex:
>>> import re
>>> re.sub(r'|'.join(map(re.escape, replace_list)), '', words)
' word2 word4, '
The above one-liner is actually not as fast as your string.replace version, but definitely shorter:
>>> words = ' '.join([hashlib.sha1(str(random.random())).hexdigest()[:10] for _ in xrange(10000)])
>>> replace_list = words.split()[:1000]
>>> random.shuffle(replace_list)
>>> %timeit remove_multiple_strings(words, replace_list)
10 loops, best of 3: 49.4 ms per loop
>>> %timeit re.sub(r'|'.join(map(re.escape, replace_list)), '', words)
1 loops, best of 3: 623 ms per loop
Gosh! Almost 12x slower.
But can we improve it? Yes.
As we are only concerned with words what we can do is simply filter out words from the words string using \w+ and compare it against a set of replace_list(yes an actual set: set(replace_list)):
>>> def sub(m):
return '' if m.group() in s else m.group()
>>> %%timeit
s = set(replace_list)
re.sub(r'\w+', sub, words)
...
100 loops, best of 3: 7.8 ms per loop
For even larger string and words the string.replace approach and my first solution will end up taking quadratic time, but the solution should run in linear time.
['apple', 'banana'], and the string is'banappleana', should that become''or'banana'? Your current code would produce''.