PyCharm is no longer recognizing Python files. The interpreter path is correctly set.

Please check File | Settings (Preferences on macOS) | Editor | File Types, ensure that file name or extension is not listed in Text files.
To fix the problem remove it from the Text files and double check that .py extension is associated with Python files.
Setting | Editor | File Types. (2017.3.2)New > File instead of New > Python File. It created an text file with no extension. When I manually added a .py extension to the filename, PyCharm automatically created a rule to treat that filename as a text file.I had a similar problem where certain .py files were showing up as regular text files after completion, thus rendering the code without syntax coloring, tab completion features, etc. Through using this post as a starting point for debugging the issue, I found the following:
Recognized File Types (in my case, Text Files)Registered Patterns were the names of the files that I was having naming/syntax issues with. I clicked on each of those and then clicked on the - for each in turn to remove them from the Registered Patterns list.ApplyI had a similar problem and none of the answers already submitted helped to resolve it.
I eventually discovered that my affected filename was listed in the
Auto-detect file type by content section in Preferences->Editor->File Types. Removing the filename from there and apply the changes resolved my issue immediately.
I accidently made a text file myfilename, renamed it to the myfilename.py version but it stayed with text file formatting even after the extension change. 
Here's how I fixed it for For PyCharm 2017.2 for Windows.
File > Settings > Editor > File Types > TextRegistered Patterns, I found the new myfilename.py in the list. - buttonOkGot it to work finally!
I had this same problem. I tried removing the pycharm caches in the ~/Library folders to no avail. Kept saying in the log that "Some skeletons failed to generate..."
So, here is what worked.
The most common issue is that you have .py in your txt file types
The other one that happens every now and again, is that you have associated the actual file name to the txt file type
Solution remains the same
navigate to file->settings->file types->text files and look for .py or the "file name" that is being formatted as text
foo) and hit enter.foo to foo.py thinking that I need a file name. 4. I renamed the file to foo.py thinking it didn't work or something. 5. Now the file is named foo.py and I have a rule saying that foo.py is a text file.I faced a similar issue on PyCharm 2021.1. As mentioned in the other solutions, the .py file that was being rendered as a text file was not present in the following menu:
File | Settings | Editor | File Types | Recognized File Types | Text | File name patterns
The following worked for me instead:
Select the file in the editor | File | File properties | Associate with File Type...
There is a section called "File type auto-detected by file content" under Editor->File Types->Recognized File Types, my file was listed, after removing from there, it got formatted to python
To revive an old conversation here, none of the above answers worked for the newer version of PyCharm due to updates. Upon creating new .py files they were being detected as .txt files and thus not able to run the files, as many others experienced above. I did not get any errors, there was just not any ability to run the file even though it had a .py extension because it was not being detected as a Python file.
PyCharm Version: 2020.1.4 Build: 201.8743.11
Here's what works instead now:
File > Manage IDE Settings > Restore Default Settings
The only problem with this is if you've added a lot of custom settings you'll have to go back in and add them again.
I had a text file that was not recognized by Pycharm as .py after I changed its ending on Windows. The solution was to right click on it in the Project menu (the one on the left that details all files in the project). One of the options was Override File Type. Changing that to Python was successful.
I had the same situation here. Ubuntu 18 - PyCharm2022.1.1 (Community Edition).
Solved as mention above with the right click above the file type.
Note: Remember to write the correct extension for Python which is .py in most cases. You can check the extension types in File, Settings, Editor, Code Style, File Types.
I hope it help, regards.
Had a similar issue after changing the project name and the above didn't help (it kept using an old interpreter). What did help was the following:
Keep coding happily :)
p.s. my error message was of the following form:
Error running ...: Cannot run program "...\python.exe" (in directory "C:\Users\pathToProject"): CreateProcess error=2, The system cannot find the file specified
I've tried many methods. My pycharm version is 2020. I've checked the settings and file types, and both are OK. Finally, I got my solution from the link below.
I right-click the XXX_XXX.py (error file) file, click overwrite file type, and then choose python. Problem solved.
right click on urls.py -> Override File Type -> Python
software tools commonly used by programmersis listed in the FAQ sectionWhat kind of questions can I ask here?, it's exactly this case. Why voting to close it?