uricase

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Related to urate oxidase: uricase, allopurinol

uricase

(ˈjʊərɪˌkeɪz)
n
(Biology) an enzyme found in organisms from bacteria to mammals but absent in humans
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Urate oxidase, or uricase, is an enzyme present in most mammals that oxidizes uric acid to the water-soluble and readily excreted metabolite allantoin.
Tumor Lysis Syndrome
Substitution of allopurinol with urate oxidase has been reported to decrease the incidence and severity of TLS (22), (23).
Hyperuricemia and tumor lysis syndrome in children with non-Hodgkin's lymphoma and acute lymphoblastic leukemia / Non-Hodgkin lenfoma ve akut lenfoblastik losemili cocuklarda hiperurisemi ve tumor lizis sendromu
Also, looking good in phase II clinical trials for long-term urate lowering to prevent recurrent attacks of gout is a pegylated form of urate oxidase, Dr.
Allopurinol doesn't work? Here's how to lower urate
Also, looking good in phase II clinical trials for long-term urate lowering to prevent recurrent attacks of gout is a pegy-lated form of urate oxidase. Thomas Bardin, M.D., noted at the annual European congress of rheumatology.
New gout drugs are expected, but until then ..
ALLN-346 is an orally administered, novel urate oxidase that has been optimized for stability in the gastrointestinal tract.
Allena Pharmaceuticals completes animal proof-of-concept study for ALLN-346
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase. Arthritis Res Ther.
Update on the management of hyperuricemia and gout
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