thromboxane


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throm·box·ane

 (thrŏm-bŏk′sān)
n.
Any of several compounds, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
[thromb(o)- + ox(o)- + -ane.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

thromboxane

(θrɒmˈbɒkseɪn)
n
a substance formed from prostaglandin precursors in platelets that promotes the constriction of blood vessels and aids blood clotting
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

throm•box•ane

(θrɒmˈbɒk seɪn)

n.
a compound, C20H32O5, formed in blood platelets, that constricts blood vessels and promotes clotting.
[1975; thromb (us) + ox- + -ane]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
This risk reduction is due to the antiplatelet effects of aspirin: inhibiting production of thromboxane decreases activation and clumping of platelets.
NSAIDs: risks and benefits
Its antiplatelet mechanism is different from the action of aspirin on prostaglandin E2 and thromboxane A2.
Aspirin in combination with clopidogrel in the treatment of acute myocardial infarction patients undergoing percutaneous coronary intervention
Aspirin inhibits platelet cyclooxygenase and thromboxane A2 and has been the most widely used antiplatelet agent.
TRENDS IN PRESCRIBING ANTIPLATELET DRUGS FOR SECONDARY PREVENTION OF NON-CARDIOEMBOLIC ISCHEMIC STROKE
Effect of endogenously produced leukotrienes and thromboxane on renal vascular resistance in rabbit hydronephrosis.
THE CORRELATION OF RENAL RESISTIVE INDEX AND SERUM CREATININE IN PREDICTING RENAL FUNCTION IN ACUTE URETERAL OBSTRUCTION
Currently, the rationale for using aspirin to prevent preeclampsia lies with its ability to inhibit platelet production of thromboxane and block NF-kB, a protein complex that plays a role in systemic and /or decidual inflammation.
The value of low-dose aspirin for prevention of preeclampsia
Some authors have suggested the ventricular dysfunction is secondary to either pulmonary hypertension caused by serotonin and thromboxane or systemic hypotension caused by vagal stimulation [1,11].
Atypical Amniotic Fluid Embolism Managed with a Novel Therapeutic Regimen
(12,13) The specific inhibition of COX-2 alters the balance between platelet-derived thromboxane [A.sub.2] ([TXA.sub.2]) and endothelium-derived [PGI.sub.2], leading to increases in the risk of thrombosis due to altered vascular tone.
Prostaglandin terminal synthases as novel therapeutic targets
Patients were considered nonresponsive (not protected) if their serum thromboxane level remained high enough to raise the risk of blood clotting within 72 hours after taking three doses of aspirin.
Why aspirin may not always prevent a heart attack: researchers uncover a new reason for "aspirin resistance"
Inhibitory effects of resveratrol on platelet activation induced by thromboxane a(2) receptor agonist in human platelets.
Greatest threat to longevity
Thromboxane [A.sub.2] ([TXA.sub.2]) is mainly derived from platelets and vascular endothelial cells.
Downregulation of Thromboxane [A.sub.2] Receptor Occurs Mainly via Nuclear Factor-KappaB Signaling Pathway in Rat Renal Artery
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