The ICD-O classification includes further morphological codes, such as balloon cell M, regressing M, amelanotic M, M in junctional nevus, M in precancerous melanosis, desmoplastic M, neurotropic M, mucosal lentiginous M, M in giant pigmented nevus/congenital melanocytic nevus, mixed epithelioid and
spindle cell M, epithelioid cell M,
spindle cell M (not otherwise specified),
spindle cell M (type A),
spindle cell M (type B), and malignant blue nevus (3).
Sarcomatoid carcinoma (SaC) is a rare variant of squamous cell carcinoma with sarcomatoid features having biphasic characteristic malignant mesenchymal
spindle cell and squamous cell component comprising of dysplasia, carcinoma in situ, or invasive carcinoma.
Keywords: Parotid gland, Dermatofibrosarcoma,
Spindle cell lesion, Recurrence, Salivary gland.
Fifteen (55.5%) tumors were
spindle cell tumors, 7 (25.9%) were epithelioid tumors, and 5 (18.5%) were mixed form tumors (Figure 6).
Most tumors were
spindle cell type n=53 (84.1%) followed by pure epithelioid type n=5 (7.9%) and mixed spindle and epithelioid type, n=4 (6.3%).
Cells with variable atypia and view of
spindle cell neoplasm containing lots of collagen fibers are remarkable in H and E staining.
DIAGNOSTIC APPROACH TO CUTANEOUS
SPINDLE CELL NEOPLASMS
Mycobacterial
spindle cell pseudotumour (MSP) is a rare inflammatory benign pseudotumour which was first reported by Wood et al.
The pathological differential diagnosis includes pleomorphic dermal sarcoma,
spindle cell squamous cell carcinoma, malignant melanoma, and leiomyosarcoma [4].
Microscopy revealed a
spindle cell and sclerosing rhabdomyosarcoma (Figure 4).
The differential diagnosis of IMT comprises low grade myofibroblastic sarcomas as well as a long list of benign, reactive, or neoplastic
spindle cell lesions, such as leiomyoma, solitary fibrous tumor,
spindle cell carcinoma, nodular fasciitis, peripheral nerve sheath tumor, and sex cord stromal tumors.
Histologically, the major differential diagnostic considerations are malignant
spindle cell tumors and fibromatosis [1].