(1972) The migration of
lymphocytes across the vascular endothelium in lymphoid tissue.
Ahn, "Differences in immunophenotyping of mucosal
lymphocytes between ulcerative colitis and Crohn's disease," The Korean Journal of Internal Medicine, vol.
Nodular
lymphocyte predominant Hodgkin lymphoma (NLPHL) is a rare lymphoma derived from germinal center B
lymphocytes that represents about 5% of all Hodgkin lymphomas in Western countries [1].
NLR is measured by dividing the number of neutrophils by the number of
lymphocytes. NLR may be an indicator of systemic inflammation, as neutrophils and
lymphocytes are thought to be significant in tumour immunology and inflammation.
The findings of recent years suggests the possibility of a common pathogenic pathway in the course of the development of atopy, allergy and autoimmunity, as these processes are interrelated by a perturbation of the functioning of immune system where
lymphocytes play a central role [1-4].
Tak and Sengul (1) noted that "It can be assumed that hematologic parameters such as neutrophils,
lymphocytes, and platelets are easily affected by various conditions, or may be due to the small number of patients.
It has been more than a century after recognition of various numbers of
lymphocytes in malignant tumors.
As an immune constituent, T
lymphocytes are essential for adaptive immunity against the invasion of pathogens.
Platelets and
lymphocytes share regulatory mechanisms in the pathophysiology of thrombosis, inflammation, immunity, and atherosclerosis.
The significant low value of NLR that observed in Group II is simply due to the difference between the mean values of neutrophil and
lymphocytes were -1.2% and + 0.34% respectively.
After the return of spontaneous circulation (ROSC), OHCA patients present with a 'sepsis-like' syndrome, which is characteristic of the high levels of circulating cytokines and the presence of endotoxin in plasma.[1],[2] In vitro , the cytokine production and proliferation abilities of circulatory
lymphocytes of OHCA patients were impaired.[2],[3],[4] This is similar to
lymphocytes observed in sepsis.[5] After ROSC, OHCA patients are prone to infection, and infections occur in more than 2 out of 3 OHCA patients after successful resuscitation during hospitalization.[6],[7],[8] Therefore, immune dysregulation is an important feature of OHCA patients after ROSC.