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As automated tools accelerate both the discovery and the exploitation of software vulnerabilities, organizations must redesign their defences and workflows to keep pace.
In vivo ligation of clinically used therapeutic antibodies via bioorthogonal click chemistry to antibody–drug conjugates leads to enhanced antitumour activity in heterogeneous and treatment-resistant tumours.
Naked mole-rat (Heterocephalus glaber) queens produce isopropyl myristate, a low-volatility ester that high-ranking animals detect and avoid, which alters prolactin and progesterone in other females to suppress reproduction and preserve eusocial hierarchy.
Satellite imagery and machine learning used for the mapping of six seminatural open wetland types and land-use disturbance in European countries shows that wetlands are highly fragmented and have uneven restoration needs.
A 54-qubit realization of non-Abelian S3 topological order demonstrates that combining anyon braiding with fusion enables universal topological quantum computation.
Scenario simulations using global economic models show that by 2050 the transformation of food systems towards healthy diets, improved productivity and halving of food waste result in a restructuring of global agriculture.
A new class of materials, quantum statistical plasmonic metacrystals, is described, which can selectively transmit different types of light based only on their quantum coherence, showing bands of allowed and forbidden photon statistics.
A molten salt, high-pressure synthesis method enables solution-based production of diverse refractory metal nitride nanocrystals, expanding access to technologically important nitride materials for advanced applications.
A Bayesian generative framework that integrates longitudinal electronic health records with genetic data to identify latent disease signatures is presented.
Elastic instabilities in mechanical metamaterials can be harnessed to programme fracture behaviour, transforming instability from a failure mechanism into a design principle that increases fracture energy by up to tenfold.
The saturation of geomagnetic activity with solar wind strength can be explained by a regression to the mean effect, suggesting that the impact of extreme geomagnetic storms can be twice as large as previously thought
