The olive nerite snail, Neritina reclivata, is irregularly distributed along coastal regions in the Gulf of Mexico and Caribbean Sea (Lehman and Hamilton, 1981).
Preliminary studies of secondary metabolites from seaweeds have shown biological activity against bacteria (Sieburth and Conover, 1965), Mytilus edulis larvae (Katsuoka et al., 1990), bryozoan (Bugula neritina) larvae (Schmitt et al., 1995) and Balanus amphitrite larvae (Willemsen, 1994).
Another chemotherapeutic agent is Bryostatin-1(Bryo-1) which is a macrocyclic lactone isolated from the marine bryozoan Bugula neritina. It is an activator of the serine-threonine kinase PKC, an enzyme involved in diverse cellular processes including cell proliferation, differentiation, and stimulus--response coupling (24), (25).