No granuloma,
hyalinization or perforation was detected.
Using histopathology they found an increase in hyperplasia and
hyalinization in syncytial nodules and stromal cells of the placenta.
In contrast to BSNS, they often exhibit alternating hypocellular and hypercellular areas with more stromal
hyalinization, and, similar to synovial sarcomas, can have thick bands of "ropey" collagen.
Cytologic atypia, loss of the muscularis mucosa layer, submucosal fibrosis,
hyalinization, presence of atrophy in the lymphoid tissue, and presence of acellular mucin inside the appendiceal wall were the histological findings leading to a correct diagnosis.
There was stromal
hyalinization between trabeculae.
Diffuse vascular
hyalinization was present throughout the tumor.
Stromal
hyalinization occurs in the majority of cases and ranges from mild perivascular
hyalinization to dense
hyalinization (Figure 1(c)).
Paneth and neuroendocrine cells with focal
hyalinization of the stroma could be identified in a subset of cases [3].
Pigmentation associated with a small number of inflammatory cells and
hyalinization of collagen fibers was detected in the superficial dermis.
The underlying stroma consisted of a variably cellular, benign spindle cell proliferation with an associated background of
hyalinization [Figure 2], calcification and ossification [Figure 3], and focal chondroid change [Figure 4] in a vague lobule-like arrangement.
The histopathological results were negative for arteritis, autoimmune pathology, or infection, and only changes related to coronary artery disease, i.e., media disruption with focal calcification and
hyalinization with lipid and cholesterol crystal deposits were found.
Phase I lesions are reported in all species lacking dystrophin (humans, mice, dogs and cats) and are characterized by
hyalinization, hypertrophy, intracellular accumulation of calcium salts and necrosis with subsequent regeneration of myofibers to compensate degeneration, in addition to the expressive inflammatory response (NGUYEN et al., 2002; MIYAZATO et al., 2011a; MIYAZATO et al., 2011b).
Its characteristic histopathological features are defined as a patternless form of growth, spindle cells, hypo- and hypercellular sites, keloid-like
hyalinization, neural type palisade formation, and ectatic branching vasculature.10
