A 31-year-old man presented with the following complaints: (a)
depigmented patches over hands and genitalia of 2 months; (b) erythematous itchy papules over limbs, trunk, head and neck of 3 months; (c) patchy hair loss over beard and scalp of 6 months without any prior medication.
Description ([female]).--Body: medium-sized hypogean species with weak troglomorphic facies and
depigmented integument; weak hispid granulation on lateral surfaces of carapace, on cheliceral hand, on base of fixed chelal finger and distally on ventral part of chelal hand.
Depigmented skin lesions were also found that time on the right shoulder and chest.
During the follow-up period, the patient developed multiple
depigmented patches around the lips, trunk, and periorbital and inguinal area, which are typical of vitiligo.
Lee, "
Depigmented genital extramammary Paget's disease: a possible histogenetic link to Toker's clear cells and clear cell papulosis," Journal of Cutaneous Pathology, vol.
Therefore, extrapolating these results to the cattle species, the same arguments can be used to justify the greater fragility observed in
depigmented hooves when compared to pigmented hooves (Rabelo et al.).
a) A large distended
depigmented CHRPE now impinging on the optic nerve head
Halo nevus (HN) usually occurs as a
depigmented halo around a melanocytic nevus.[1],[2] Although the pathogenesis of HN remains unclear, the lesion-infiltrating CD8+ T-lymphocytes are regarded as having a key role in the immune-mediated melanocytic degeneration in this condition.[3],[4],[5] HN has been shown to be associated with many autoimmune diseases, of which vitiligo is the most closely related.[2],[6] Currently, no standard signs are available to identify HN patients at risk of vitiligo, and the relevant data obtained in previous studies are somewhat conflicting.[7],[8],[9] This study aimed to identify factors affecting the presence of vitiligo in HN patients using uni- and multi-variate analyses.
It is characterized by discrete or confluent scaly, discolored or
depigmented patches mainly on the upper trunk1.
[7] In the case report by Wong et al., a biopsy was taken from one of the patients and it showed that the number of melanocytes in the
depigmented lesions was fewer than the patient's normal skin and dendritic processes were decreased.
They had
depigmented hairs, skin and iris along with reduced visual acuity, photophobia and exhibited continuous symptoms of nystagmus.
Thirty six subjects regularly use cosmetics depigmentation (
depigmented group), and thirty-six were non-pigmented black skin (control group).
Well marginated, irregularly bordered
depigmented macules and patches were seen on distal part of fingers that were negative for vitiligo on Wood's lamp examination.
The examination was normal except for a pigmented choroidal nevus OD with a
depigmented halo around it.
