Liquid chromatographic determination of mexiletine and tocainide in human plasma with fluorescence detection after reaction with a modified o-phthalaldehyde reagent.
As a significant drawback in this book, in the opinion of this reviewer, that gas chromatographic separations would deserve at least one chapter with an appropriate treatment of basic principles and presentation of some of many outstanding separation examples, especially using open tubular columns coated with novel chiral stationary phases.
The chromatograms of 10 batches aqueous extract intermediate of medicinal material, alcohol extract intermediate of medicinal material and Tianshu capsule samples in HPLC modes were used to establish reference HPLC fingerprints I, II and III respectively, by professional software named Similarity Evaluation System for Chromatographic Fingerprint of Chinese traditional medicine(TCM) (Version 2004A), which was recommended by China food and drug administration (SFDA) for evaluating similarities of chromatographic profiles.
State-of-the-art analytical equipment includes spectroscopy, thermal analysis and chromatographic techniques used to troubleshoot manufacturing quality concerns, determine raw material impurities and characterize trace level additives.
Chidiac-Tannoury entitled "Lactic Acid Dimer: An Artifact in the Gas Chromatographic Analysis of Urine with Massive Lactic Acid Aciduria" contained an error printer regrets the error.
With a series of chromatographic, spectroscopic and synthetic techniques-- coupled with the use of their noses--chemists at Kraft's Basic Flavor group in Glenview, Ill., found the culprit: 4, 4, 6-trimethyl-1, 3-dioxane, formed by the reaction between formaldehyde and a solvent coating used to help ink adhere to the film.