Sickle-cell disease, also known as
sickle-cell anemia, is a group of disorders that lead to deformation and break down of red blood cells.
have
sickle-cell disease, most of them African-Americans and Latinos but also people of Middle Eastern, Asian, Indian, and Mediterranean descent.
Sickle-cell anaemia occurs when abnormal haemoglobin makes the red blood cells to become sickleshaped and burst at low oxygen levels.
And like sickle cell, it dramatically shortens patients' life spans--to a median of 37 years for cystic fibrosis, compared to 40 to 45 years for
sickle-cell disease.
Sickle-cell trait as a risk factor for sudden death in physical training.
A preliminary study of
sickle-cell patients with pulmonary hypertension suggests that they can benefit from sildenafil, a blood vessel dilator marketed as the impotence drug Viagra by the New York--based drug company Pfizer.
Using his "designer" mice, Townes plans to test, treatments to relieve or even cure
sickle-cell disease.
Sickle-cell trait and small-for-gestational age babies: Is there a link?
London, June 26 (ANI): King Tutankhamun's death was a result of
sickle-cell disease, and not malaria - according to experts.
A protein found on red blood cells in
sickle-cell disease binds these cells to blood vessel walls, disrupting circulation, a new study suggests.
If S% is greater than A%, then the smaller 'A' has come from a beta-Thalassaemia gene, and the patient has
sickle-cell beta-Thalassaemia (Ache/Ache), not sickle cell trait.
Characterised by abnormal blood cells that have a tendency to take on a rigid, sickle-like shape, the disease leaves sufferers prone to a number of acute and chronic health problems such as infection, attacks of severe pain known as "
sickle-cell crisis" and stroke.
Stem cell transplants have long been a therapy option for children with life-threatening cases of
sickle-cell disease, but the procedure itself can be deadly.
By installing a designer gene that offsets the adverse effects of faulty DNA, scientists have prevented
sickle-cell disease in mice.
"There are simply so many ways it might work that there's a growing excitement about using nitric oxide for
sickle-cell disease," Gladwin says.
