Tenuivirus (taxid:12329)
VIRION
Virions consist of four to five non enveloped nucleocapsids, about 3-10 nm in diameter
GENOME
The genome is segmented and consists of four or five segments of linear negative-sense and ambisense single-stranded RNA. The complete genome is around 16 kb.
GENE EXPRESSION
The viral RNA dependent RNA polymerase (L) binds to a promoter on each encapsidated segment, and transcribes the mRNAs. These are capped by L protein during synthesis using cap snatching . Segments 2, 3 and 4 are ambisens.
ENZYMES
REPLICATION
CYTOPLASMIC
- Virus enters into host cells by mechanical injection or through plasmodesmatas
- Transcription, viral mRNAs are capped in the cytoplasm.
- Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
- The ribonucleocapsids migrates to new cells using movement proteins.
Matching UniProtKB/Swiss-Prot entries
(all links/actions below point to uniprot.org website)18 entries grouped by protein
1 entry
Putative envelope glycoprotein (GP) (Protein pc2)
1 entry
RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) (Transcriptase)
3 entries
Movement protein (Non-structural protein 4) (NS4) (Protein pc4)
4 entries
Nucleoprotein (Coat protein) (CP) (Nucleocapsid protein) (Protein N) (Protein pc3)
3 entries
Major non-capsid protein (NCP) (20.5 kDa protein) (Protein p4) (Stripe disease-specific protein) (Protein S)
1 entry
Protein p2
1 entry
Non-structural protein NS5
4 entries