tRNA Maturation: RNA Polymerization without a Nucleic Acid Template
Abstract
The CCA-adding enzyme, which builds and repairs the 3' terminal CCA sequence of tRNA, is the only RNA polymerase that can synthesize a defined nucleotide sequence without using a nucleic acid template. New cocrystal structures tell us how this remarkable enzyme works.
- Publication:
-
Current Biology
- Pub Date:
- 2004
- DOI:
- Bibcode:
- 2004CBio...14.R883W