Evolution of ageing
Abstract
An evolutionary view of ageing suggests that mortality may be due to an energy-saving strategy of reduced error regulation in somatic cells. This supports Orgel's `error catastrophe' hypothesis and offers a new basis for the study of normal and abnormal ageing syndromes and of apparently immortal transformed cell lines.
- Publication:
-
Nature
- Pub Date:
- November 1977
- DOI:
- Bibcode:
- 1977Natur.270..301K