Inozamin-fosfat amidinotransferaza
Inozamin-fosfat amidinotransferaza (EC 2.1.4.2, L-arginin:inozamin-P-amidinotransferaza, inozamin-P amidinotransferaza, L-arginin:inozamin fosfat amidinotransferaza, inozamin-fosfatna amidinotransferaza) je enzim sa sistematskim imenom L-arginin:1-amino-1-dezoksi-scilo-inozitol-4-fosfat amidinotransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Inozamin-fosfat amidinotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.4.2 | ||||||||
| CAS broj | 52227-63-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- L-arginin + 1-amino-1-dezoksi-scilo-inozitol 4-fosfat L-ornitin + 1-guanidino-1-dezoksi-scilo-inozitol 4-fosfat
1D-1-guanidino-3-amino-1,3-didezoksi-scilo-inozitol 6-fosfat, streptamin fosfat i 2-dezoksistreptamin fosfat mogu takođe da deluju kao akceptori. Kanavanin može da bude donor.
Reference
uredi- ↑ Walker, M.S. and Walker, J.B. (1966). „Enzymic studies on the biosynthesis of streptomycin, transamidation of inosamine and streptamine derivatives”. J. Biol. Chem. 241: 1262-1269. PMID 5935341.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.