2018
DOI: 10.1111/ajo.12773
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The levonorgestrel‐releasing intrauterine system is associated with a reduction in dysmenorrhoea and dyspareunia, a decrease in CA 125 levels, and an increase in quality of life in women with suspected endometriosis

Abstract: Several favourable outcomes were found following LNG-IUS insertion: (i) dyspareunia and dysmenorrhoea were clearly reduced; (ii) the size of endometriomas were decreased; (iii) CA 125 levels significantly decreased; (iv) a few women experienced the typical systemic adverse effects of progestogens; however, LNG-IUS-related adverse events were generally tolerable and the discontinuation rate was as low as 6.66% (3/45).

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Cited by 36 publications

(21 citation statements)
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“…The limitations of this study include the eventual small sample size from within a larger study. The sample size is, however, comparable with similar studies on the topic [33]. As a questionnaire-based study, our results are potentially impacted by the differences in responders and non-responders, with almost a third of patients failing to complete a survey 6-18 months following insertion.…”
Section: Discussionsupporting
confidence: 77%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The limitations of this study include the eventual small sample size from within a larger study. The sample size is, however, comparable with similar studies on the topic [33]. As a questionnaire-based study, our results are potentially impacted by the differences in responders and non-responders, with almost a third of patients failing to complete a survey 6-18 months following insertion.…”
Section: Discussionsupporting
confidence: 77%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Among these, 32 studies were excluded for the following reasons: abstract only or conference proceeding (n520), absence of extractable data (n55), full text not available (n54), ineligible setting (n52), absent outcome of interest (n51). The remaining full-text articles included in this systematic review originated from Italy, [7][8][9][10][11][12][13][14][15][16][17][18] Japan, [19][20][21][22][23][24][25][26][27][28][29] Turkey, 4,30,31 the United States, [32][33][34] India, 35 Thailand, 36 Denmark, 37 and the United Arab Emirates. 38 See Figure 1 for the PRISMA flow diagram.…”
Section: Resultsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Of these studies, 18 aimed to evaluate the effect of the medical treatment for endometriosis on QoL [46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62][63]. The remaining 19 studies aimed to evaluate the impact of surgical treatment upon QoL in endometriosis [64][65][66][67][68][69][70][71][72][73][74][75][76][77][78][79][80][81][82].…”
Section: Resultsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.