2018 The levonorgestrel‐releasing intrauterine system is associated with a reduction in dysmenorrhoea and dyspareunia, a decrease in
The levonorgestrel‐releasing intrauterine system is associated with a reduction in dysmenorrhoea and dyspareunia, a decrease in CA 125 levels, and an increase in quality of life in women with suspected endometriosis
Abstract: Several favourable outcomes were found following LNG-IUS insertion: (i) dyspareunia and dysmenorrhoea were clearly reduced; (ii) the size of endometriomas were decreased; (iii) CA 125 levels significantly decreased; (iv) a few women experienced the typical systemic adverse effects of progestogens; however, LNG-IUS-related adverse events were generally tolerable and the discontinuation rate was as low as 6.66% (3/45).
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Cited by 36 publications
(21 citation statements)
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“…The limitations of this study include the eventual small sample size from within a larger study. The sample size is, however, comparable with similar studies on the topic [33]. As a questionnaire-based study, our results are potentially impacted by the differences in responders and non-responders, with almost a third of patients failing to complete a survey 6-18 months following insertion.…”
Section: Discussionsupporting
confidence: 77%
“…The limitations of this study include the eventual small sample size from within a larger study. The sample size is, however, comparable with similar studies on the topic [33]. As a questionnaire-based study, our results are potentially impacted by the differences in responders and non-responders, with almost a third of patients failing to complete a survey 6-18 months following insertion.…”
Section: Discussionsupporting
confidence: 77%
“…Among these, 32 studies were excluded for the following reasons: abstract only or conference proceeding (n520), absence of extractable data (n55), full text not available (n54), ineligible setting (n52), absent outcome of interest (n51). The remaining full-text articles included in this systematic review originated from Italy, [7][8][9][10][11][12][13][14][15][16][17][18] Japan, [19][20][21][22][23][24][25][26][27][28][29] Turkey, 4,30,31 the United States, [32][33][34] India, 35 Thailand, 36 Denmark, 37 and the United Arab Emirates. 38 See Figure 1 for the PRISMA flow diagram.…”
Section: Resultsmentioning
confidence: 99%
“…Of these studies, 18 aimed to evaluate the effect of the medical treatment for endometriosis on QoL [46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62][63]. The remaining 19 studies aimed to evaluate the impact of surgical treatment upon QoL in endometriosis [64][65][66][67][68][69][70][71][72][73][74][75][76][77][78][79][80][81][82].…”
Section: Resultsmentioning
confidence: 99%
