Langenbecks Arch Surg
 2014
DOI: 10.1007/s00423-014-1221-7
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Improvement of quality of life in patients with benign goiter after surgical treatment

Branka Bukvić
1
,
Vladan Živaljević
2
,
Sandra Šipetić Grujičić
3
et al.

Abstract: QoL in patients with benign thyroid diseases improves significantly after operative treatment, independent of the extent of the operation.

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Cited by 29 publications

(65 citation statements)
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“…Goitre symptoms continued to show significant improvement over time. This finding is in agreement with other studies, where goitre symptoms all showed significant improvement following surgery for benign thyroid disease 7–12 . Goitre‐related symptoms, namely dysphagia, dyspnoea, voice change and neck discomfort, have previously been reported in separate QOL studies.…”
Section: Discussionsupporting
confidence: 93%
“…In keeping with similar ThyPRO studies looking at thyroidectomy for benign disease, tiredness was the most impaired pre‐operative domain and showed statistically significant improvement post‐operatively 7–12 . In our study, tiredness was the also most impaired score, with a baseline score of 57.1.…”
Section: Discussionsupporting
confidence: 90%
“…Baseline anxiety, depressivity and cognition domain scores showed statistically significant improvement at 6 months post‐operatively. This is consistent with the published literature, which demonstrates significant post‐operative improvement in anxiety scores both for toxic and non‐toxic patients 3,8–12 . Baseline questionnaires were administered on the day of pre‐anaesthetic assessment and may reflect anxiety regarding upcoming surgery.…”
Section: Discussionsupporting
confidence: 87%
See 2 more Smart Citations
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Goitre symptoms continued to show significant improvement over time. This finding is in agreement with other studies, where goitre symptoms all showed significant improvement following surgery for benign thyroid disease 7–12 . Goitre‐related symptoms, namely dysphagia, dyspnoea, voice change and neck discomfort, have previously been reported in separate QOL studies.…”
Section: Discussionsupporting
confidence: 93%
“…In keeping with similar ThyPRO studies looking at thyroidectomy for benign disease, tiredness was the most impaired pre‐operative domain and showed statistically significant improvement post‐operatively 7–12 . In our study, tiredness was the also most impaired score, with a baseline score of 57.1.…”
Section: Discussionsupporting
confidence: 90%
“…Baseline anxiety, depressivity and cognition domain scores showed statistically significant improvement at 6 months post‐operatively. This is consistent with the published literature, which demonstrates significant post‐operative improvement in anxiety scores both for toxic and non‐toxic patients 3,8–12 . Baseline questionnaires were administered on the day of pre‐anaesthetic assessment and may reflect anxiety regarding upcoming surgery.…”
Section: Discussionsupporting
confidence: 87%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…These results are similar to those found in the literature (21,22,23,24,25,26,27,28). At the second postoperative month evaluation, a statistically significant improvement was already observed for GH and MH scores, whereas the RP score was significantly decreased, before increasing above baseline values at month 6.…”
Section: Discussionsupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Similar to Group H, there were no decreases in “hypothyroidism symptoms,” “tiredness,” “appearance,” and “general QoL” domains in Group L. Additionally, “eye symptoms” domain was decreased in Group L. In assessment of whole cohort overall there were no significant differences in domains of “impaired daily life,” “emotional susceptibility,” “appearance,” and “eye symptoms” in postoperative compared to preoperative period, domains other than “emotional susceptibility” were valued<3. Similarly, these domains were also below three in study published by Bukvic et al [16] ; however, they showed a significant decrease after surgery, contrary to present study.…”
Section: Discussioncontrasting
confidence: 90%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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