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Review
. 2023 Apr 5:636:122817.
doi: 10.1016/j.ijpharm.2023.122817. Epub 2023 Mar 9.

Unconventional and conventional Pickering emulsions: Perspectives and challenges in skin applications

Bianca Hazt  1 , Gabriela Pereira Parchen  2 , Lilian Fernanda Martins do Amaral  3 , Patrícia Rondon Gallina  4 , Sandra Martin  5 , Odinei Hess Gonçalves  6 , Rilton Alves de Freitas  7
Affiliations
Free article
Review

Unconventional and conventional Pickering emulsions: Perspectives and challenges in skin applications

Bianca Hazt et al. Int J Pharm. .
Free article

Abstract

Pickering emulsions are free from molecular and classical surfactants and are stabilized by solid particles, creating long-term stability against emulsion coalescence. Additionally, these emulsions are both environmentally and skin-friendly, creating new and unexplored sensorial perceptions. Although the literature mostly describes conventional emulsions (oil-in-water), there are unconventional emulsions (multiple, oil-in-oil and water-in-water) with excellent prospects and challenges in skin application as oil-free systems, permeation enhancers and topical drug delivery agents, with various possibilities in pharmaceutical and cosmetic products. However, up to now, these conventional and unconventional Pickering emulsions are not yet available as commercial products. This review brings to the discussion some important aspects such as the use of phases, particles, rheological and sensorial perception, as well as current trends in the development of these emulsions.

Keywords: Cosmetics; Drug delivery; Pharmaceutical; Pickering emulsions; Topical.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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