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Case Reports
. 1999 Feb;23(2):353-7.
doi: 10.1016/s0278-5846(98)00098-0.

Possible association between delusional disorder, somatic type and reduced regional cerebral blood flow

T Wada  1 , S Kawakatsu, A Komatani, N Okuyama, K Otani
Affiliations
Case Reports

Possible association between delusional disorder, somatic type and reduced regional cerebral blood flow

T Wada et al. Prog Neuropsychopharmacol Biol Psychiatry. 1999 Feb.

Abstract

1. A 78-year-old female with DDST and pain disorder was treated by clomipramine 20-100 mg/day. The hypochondriacal delusion was completely resolved, while the pains were partially resolved. 2. The SPECT using Xe-133 taken at the early stage of clomipramine treatment, when she still had hypochondriacal delusions, showed markedly reduced rCBF in the temporal and parietal lobes, with predominance on the left hemisphere. Meanwhile, the SPECT taken after resolution of the hypochondriacal delusions showed a marked improvement in the reduced rCBF. 3. This report suggests that DDST has some association with reduced rCBF in the temporal and parietal lobes.

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