Results for 'transgenerational'

165 found
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  1. Transgenerational trauma and worlded brains: an interdisciplinary perspective on ‘post-traumatic slave syndrome’.Machiel Keestra - 2023 - In Stephan Besser & Flora Lysen, Worlding the Brain. Interdisciplinary Explorations in Cognition and Neuroculture. pp. 63-81.
    Trauma and traumatization have arguably always been part of the human experience yet have in the last few decades come to occupy a prominent place in various popular and academic contexts. This chapter offers an interdisciplinary and comparative investigation of trauma and traumatization in different historical contexts. More specifically, my aim is to discuss whether the rich bodies of research in trauma and traumatization in Holocaust survivors and their descendants yield relevant insights for post-slavery contexts. It has been shown that (...)
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  2.  97
    Transgenerational Social Structures and Fictional Actors: Community-Based Responsibility for Future Generations.Tiziana Andina & Fausto Corvino - 2023 - The Monist 106 (2):150-164.
    The notion of transgenerational community is usually based on two diachronic interactions. The first interaction consists of present generations taking up the legacy (not only economic, but also institutional, artistic, cultural, and so forth) of past generations and giving it continuity, exercising a form of active agency. The second interaction occurs when present generations pass on their legacy to future generations. This is supposed to expand the boundaries of the community in a transgenerational sense (both backward- and forward-looking). (...)
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  3.  57
    Transgenerational Projects and Entangled Domination: Revisiting Autonomy in Radioactive Waste Management.Shin-Etsu Sugawara - 2025 - Science and Engineering Ethics 31 (5):1-25.
    This paper explores the ethical implications of long-term, transgenerational projects through the lens of neo-republican theory, focusing on the issue of intergenerational domination. Traditional accounts of intergenerational justice often emphasize one-directional influence from present to future generations. This study proposes a threefold generational framework—the current generation (CG), subsequent generations (SGs), and remote generations (RGs)—to better capture the temporal complexity and multi-layered dependencies that define transgenerational projects such as radioactive waste management. Building on the concept of projectual reciprocity, the (...)
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  4.  78
    Transgenerational Communitarianism in a Global Interconnected World: A Critique.Luigi Bonatti & Lorenza Alexandra Lorenzetti - 2023 - The Monist 106 (2):119-131.
    We discuss how transgenerational communitarianism deals with public decisions involving tradeoffs between different generations’ wellbeing and having global consequences. Policies for tackling climate change are an example. Although there is a natural, evolutionary, basis for intergenerational altruism, most people lack the competencies for constituting a transgenerational community. Moreover, greater attention to future generations’ wellbeing need not substitute for collective action: a lower discount rate reflecting a stronger concern for future generations may even worsen their wellbeing. Finally, in a (...)
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  5.  47
    The Transgenerational Action of Growing Old Together. Ageism and Generationism in Ageing Societies.Alessandro Anzà - 2025 - Phenomenology and Mind 28:32.
    This paper explores ageism and generationism in ageing societies through the lens of transgenerative social ontology and critical phenomenology. It argues that the everyday Lifeworld encompasses multi-age groups coexisting in the same contemporaneousness, which sets up for the constitution of personal attitudes and social interactions, both conflictual and cooperative, between people of different ages and generations. Firstly, I draw on Schützian social phenomenology, focusing on the taxonomy of consociates, contemporaries, predecessors, and successors to analyze the shared experience of growing old (...)
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  6. Transgenerational actions and responsibility.Tiziana Andina - 2018 - Journal of Critical Realism 17 (4):364-373.
    The Imperative of Responsibility, by the German philosopher Hans Jonas, is a work that aspires to a re-foundation of ethics based on an analysis of the contemporary world as well as on a prediction about the fate of globalized humanity. Through a discussion of the fundamental concepts of Jonas’ work, the essay shows that the central themes of his research, which are still very relevant today, should be addressed by moving from the ethical level to that of ontology and social (...)
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  7. Transgenerational Compensation.George Sher - 2005 - Philosophy and Public Affairs 33 (2):181-200.
  8.  62
    Transgenerational transmission in psychoanalysis: A phenomenology of dislocating errands.Maurice Apprey - 2023 - Indo-Pacific Journal of Phenomenology 23 (1).
    In the process of psychical transmission from one generation to the next, who asks what of whom? The evocative expression of an ‘errand’ suggests that a subject is sent on a mission, sent in error, wanders away, and returns home, adversely changed. A vocative imperative is at the heart of a mission. When there is a call from an anterior Other, there must be a response. Before, there was an experience of a call and its response, then, there would be (...)
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  9. Transgenerational obligations: Twenty-first century germany and the holocaust.Doris Schroeder & Bob Brecher - 2003 - Journal of Applied Philosophy 20 (1):45–57.
    Has history assigned special obligations to Germans that can transcend generation borders? Do the grandchildren of Holocaust perpetrators or the grandchildren of inactive bystanders carry any obligations that are only related to their ancestry? These questions will be at the centre of this investigation. It will be argued that five different models of justification are available for or against transgenerational obligations, namely liberalism, the unique evil argument, the psychological view, a form of consequentialist pragmatism and the community-based approach. Only (...)
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  10. Binding the Present and the Future: Transgenerational Social Actions as Joint Commitments.Costanza Penna - 2024 - Rivista di Estetica 86:196-214.
    Transgenerational social actions are collective actions that endure over a considerable period of time and require the cooperation of multiple generations. Yet, it remains unclear what kind of obligations and rights, if any, allow actions to persist through the ages, binding future generations to be part of them. This paper proposes a way forward by considering transgenerational actions as a particular type of long-term joint commitments. Drawing on plural subject theory, I explore the conditions for membership, normativity, and (...)
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  11.  77
    Transgenerational Frontiers: The Capabilities Approach And the New Challenge of Justice.Giulio Sacco - 2024 - International Journal of Philosophical Studies 32 (3):315-332.
    The aim of the paper is to confront some challenges raised by intergenerational justice from the perspective of Martha Nussbaum’s capabilities approach. After having sketched her account, the essay deals with some objections to it from an environmental perspective, arguing that, contrary to some critics, it can be a valuable basis for reflecting on our duties towards future generations. More precisely, I focus on how the CA provides promising insights to address two central problems of intergenerational ethics: 1) the so-called (...)
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  12. Bernard Stiegler on Transgenerational Memory and the Dual Origin of the Human.Michael Haworth - 2016 - Theory, Culture and Society 33 (3):151-173.
    This article reconsiders Stiegler’s account of the emergence of the human species in light of research in the field of transgenerational epigenetics. Stiegler traces this emergence to the appearance of technical artefacts allowing for the intergenerational transmission of acquired memory that would otherwise die along with the organism. This is taken to constitute a rupture in the history of life. The argument that I develop critiques Stiegler’s account at two levels: On the empirical level I argue that emerging neo-Lamarckian (...)
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  13.  65
    Transgenerational transmissions of diasporic lack of home in Jhumpa Lahiri’s The Namesake.Muhammad Zameer Nawaz & Akhtar Aziz - 2025 - Journal of Theoretical and Philosophical Psychology 45 (2):154-165.
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  14.  79
    Non‐genomic transgenerational inheritance of disease risk.Peter D. Gluckman, Mark A. Hanson & Alan S. Beedle - 2007 - Bioessays 29 (2):145-154.
    That there is a heritable or familial component of susceptibility to chronic non‐communicable diseases such as type 2 diabetes, obesity and cardiovascular disease is well established, but there is increasing evidence that some elements of such heritability are transmitted non‐genomically and that the processes whereby environmental influences act during early development to shape disease risk in later life can have effects beyond a single generation. Such heritability may operate through epigenetic mechanisms involving regulation of either imprinted or non‐imprinted genes but (...)
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  15. Transgenerational Epigenetics, or the Spectral History of the Flesh.Darian Meacham & Anna-Pia Papageorgiou - 2007 - Chiasmi International 9:65-93.
  16.  64
    Epigenetic transgenerational inheritance: Should obesity-prevention policies be reconsidered?Mihai Niculescu - 2011 - Synesis: A Journal of Science, Technology, Ethics, and Policy 2 (1):G18 - G26.
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  17. The Extended Body: Vicarious Memories and Mimetic Capacities in Transgenerational Trauma.Nathália de Ávila - 2025 - International Journal of Philosophical Studies 33 (1):50-72.
    Drawing from enactivist theory, this paper examines how certain cases of transgenerational trauma manifest as Post-Traumatic Stress Disorder in the descendants of survivors who did not experience the event directly. It argues that psychopathology develops from an embodied form of vicarious memory, conveyed through mimetic capacities and emotional resonances that involve the transfer of emotional and behavioral patterns from parents to children, affecting their sense of self. Children’s reenactments of their parents’ emotional states do not merely replay the parents’ (...)
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  18. Confucianism and Transgenerational Grounds for Justice.May Sim - 2023 - The Monist 106 (2):181-193.
    This article explores Mencius’s virtue-oriented ethics and its metaphysical foundation for resources they can provide to transgenerational communities. Mencius’s ethics offers moral norms for human actions that transcend those generations with whom they can interact and impact generations of people in the future. These actions range from the preservation of traditional values to the challenges of climate change, offering grounds for transgenerational justice. Mencius’s account of virtues offers a moral justification for the standards of living that are common (...)
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  19. From correlation to causation: The new frontier of transgenerational epigenetic inheritance.Mohd Hafiz Rothi & Eric Lieberman Greer - 2023 - Bioessays 45 (1):2200118.
    While heredity is predominantly controlled by what deoxyribonucleic acid (DNA) sequences are passed from parents to their offspring, a small but growing number of traits have been shown to be regulated in part by the non‐genetic inheritance of information. Transgenerational epigenetic inheritance is defined as heritable information passed from parents to their offspring without changing the DNA sequence. Work of the past seven decades has transitioned what was previously viewed as rare phenomenology, into well‐established paradigms by which numerous traits (...)
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  20.  50
    Heritage, community and future generations: the transgenerational quest for justice.Davide Grasso - 2023 - Rivista di Estetica 84:103-121.
    A theory of transgenerational justice ought to be grounded on intuitions shared in the human community. One is parental responsibility, postulating duties between the generating and the generated in a realm of proximity. To achieve greater political abstraction, it is necessary to deny self-sufficiency to such primary transgenerational level, arguing for its structural need to rely on external sources distant in space and time. A critical cross-examining of concepts relevant to justify the leap from proximity to distance follows (...)
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  21.  66
    Climate issue: the principle of transgenerational responsibility.Tiziana Andina - 2020 - Rivista di Estetica 75:17-32.
    The multidimensional nature of climate change makes it a complex matter, on both the theoretical and practical planes. The urgency and centrality of the issues and problems it poses are of key importance for our species and its survival. In this paper, we propose pairing the principle of common but differentiated responsibilities – the cornerstone of climate talks over the last thirty years – with the criterion of transgenerational responsibility. Such a criterion seeks to focus particular attention on the (...)
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  22. What is Responsibility Toward the Past? Ethical, Existential, and Transgenerational Dimensions.Natan Elgabsi - 2024 - History and Theory:1-24.
    Today, there is a growing interest in the ethics of the human and social sciences, and in the discussions surrounding these topics, notions such as responsibility toward the past are often invoked. But those engaged in these discussions seldom acknowledge that there are at least two distinct logics of responsibility underlying many debates. These logics permeate a Western scholarly tradition but are seldom explicitly discussed. The two logics follow the Latin and Hebrew concepts of responsibility: spondeo and acharayut. The purpose (...)
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  23.  98
    Microbiome‐Germline Interactions and Their Transgenerational Implications.Michael Elgart & Yoav Soen - 2018 - Bioessays 40 (4):1700018.
    It is becoming increasingly clear that most, if not all, animals and plants are associated with a diverse array of resident gut microbiota. This symbiosis is regulated by host-microbiome interactions which influence the development, homeostasis, adaptation and evolution of the host. Recent evidence indicated that these interactions can also affect the host germline and have a potential of supporting transgenerational effects, including inheritance of acquired characteristics. Taken together, the influence of gut bacteria on the host soma and germline could (...)
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  24. Do the Current Poor Owe Anything to Future Persons? The Transgenerational Community Principle and Prioritarianism.Avner de-Shalit - 2023 - The Monist 106 (2):105-118.
    The transgenerational community is based on moral similarity between contemporary and future people, referring to an ongoing moral deliberation across generations. It justifies obligations of justice towards the not yet born. Prioritarianism gives extra weight to the wellbeing of the least advantaged. I argue that both sentiments are egalitarian, and ask whether there is any tension between them. If we assume economic growth, and/or technological improvements and/or inflation, then prioritarianism prima facie implies that we should prefer to spend any (...)
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  25. Reading the Inscriptions of Our Lifeworld: Transgenerational Existence and the Metaphysics of the Grave.Natan Elgabsi - 2022 - Philosophy Today 66 (3):529-545.
    This existential phenomenological exploration concerns how writing is not the mere tool for communication and commemoration, or the supplementary image of a memory, but is closely connected to the phenomenon of the grave. The exploration aims to show a transgenerational mode of human existence and moral life, by considering how the becoming of a historical, which is to say a transgenerational subject through the features that writing and the grave together lets us capture, is also importantly bound to (...)
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  26.  49
    Tax Avoidance in Family Business: The Ethical Perspective of CEO Transgenerational Responsibility.Alessandro Cirillo, Maria Angela Manzi, Jonathan Bauweraerts & Salvatore Sciascia - 2025 - Journal of Business Ethics 198 (4):841-864.
    Exploring the intricacies of heterogeneity in tax avoidance practices within family firms, a growing trend acknowledges the significant role of chief executive officers (CEOs) in setting the ethical tone and shaping corporate tax strategies. However, these studies often overlook the influence of the CEO’s transgenerational orientation, which becomes crucial when assessing ethics in family businesses. Therefore, the paper aims to analyse to what extent the CEO’s transgenerational responsibility (the moral obligation that incumbent leaders have vis-à-vis next generation family (...)
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  27.  88
    Two Modes of Transgenerational Information Transmission.Nicholas Shea - 2013 - In Kim Sterelny, Richard Joyce, Brett Calcott & Ben Fraser, Cooperation and its Evolution. MIT Press. pp. 289-312.
    The explosion of scientific results about epigenetic and other parental effects appears bewilderingly diverse. An important distinction helps to bring order to the data. Firstly, parents can detect adaptively-relevant information and transmit it to their offspring who rely on it to set a plastic phenotype adaptively. Secondly, adaptively-relevant information may be generated by a process of selection on a reliably transmitted parental effect. The distinction is particularly valuable in revealing two quite different ways in which human cultural transmission may operate.
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  28.  82
    Adaptive immunity or evolutionary adaptation? Transgenerational immune systems at the crossroads.Sophie Juliane Veigl - 2022 - Biology and Philosophy 37 (5):1-21.
    In recent years, immune systems have sparked considerable interest within the philosophy of science. One issue that has received increased attention is whether other phyla besides vertebrates display an adaptive immune system. Particularly the discovery of CRISPR-Cas9-based systems has triggered a discussion about how to classify adaptive immune systems. One question that has not been addressed yet is the transgenerational aspect of the CRISPR-Cas9-based response. If immunity is acquired and inherited, how to distinguish evolutionary from immunological adaptation? To shed (...)
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  29. Extended evolutionary psychology: the importance of transgenerational developmental plasticity.Karola Stotz - 2014 - Frontiers in Psychology 5.
    What kind mechanisms one deems central for the evolutionary process deeply influences one's understanding of the nature of organisms, including cognition. Reversely, adopting a certain approach to the nature of life and cognition and the relationship between them or between the organism and its environment should affect one's view of evolutionary theory. This paper explores this reciprocal relationship in more detail. In particular it argues that the view of living and cognitive systems, especially humans, as deeply integrated beings embedded in (...)
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  30.  83
    When the Generational Overlap Is the Challenge Rather Than the Solution. On Some Problematic Versions of Transgenerational Justice.Ferdinando G. Menga - 2023 - The Monist 106 (2):194-208.
    While in the realm of scholarly debate on intergenerational justice the mechanism of a transgenerational intertwinement has been often adopted as a chief conceptual device in view of overcoming ethical short-termism and legitimizing duties towards future generations, this paper aims at showing that there are good reasons for considering the opposite outcome. Drawing on three paradigmatic examples taken from three mainstream approaches in the debate—Rawls’s contractualism, Gauthier’s contractarianism, and indirect reciprocity—I will show how the grammar of presentism is still (...)
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  31. Discursive Democracy in the Transgenerational Context and a Precautionary Turn in Public Reasoning.Genevieve Fuji Johnson - 2007 - Contemporary Political Theory 6 (1):67-85.
    We should seek to justify, from a moral perspective, policies associated with serious and irreversible risks to the health of human beings, their societies, and the environment for these risks may have great impacts on the autonomy of both existing and future persons. The ideal of discursive democracy provides a way of morally justifying such policies to both existing and future persons. It calls for the inclusive, informed, and uncoerced deliberation toward an agreement of both existing and future persons, which (...)
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  32.  79
    Climate Change, the Non-identity Problem, and the Metaphysics of Transgenerational Actions.Tiziana Andina & Fausto Corvino - 2023 - In Gianfranco Pellegrino & Marcello Di Paola, Handbook of the Philosophy of Climate Change. Cham: Springer. pp. 663-684.
    Why should one take action to move toward a greener world if doing so will cause the birth of a totally different group of future people? This chapter starts from the metaphysical evidence that many collective climate actions imply a change in the identity of future generations, as opposed to a counterfactual laissez-faire attitude. The climatic fallout from the non-identity paradox introduced by Derek Parfit is examined to determine if and how a principle of transgenerational responsibility can be defended (...)
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  33. Blurring the germline: Genome editing and transgenerational epigenetic inheritance.Tim Lewens - 2019 - Bioethics 34 (1):7-15.
    Sperm, eggs and embryos are made up of more than genes, and there are indications that changes to non‐genetic structures in these elements of the germline can also be inherited. It is, therefore, a mistake to treat phrases like ‘germline inheritance’ and ‘genetic inheritance’ as simple synonyms, and bioethical discussion should expand its focus beyond alterations to the genome when considering the ethics of germline modification. Moreover, additional research on non‐genetic inheritance draws attention to a variety of means whereby differences (...)
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  34.  31
    Uprooting Violence: Transgenerational Legacies and Entangled Memories in Ananda Devi's L'arbre fouet.Emmanuel Bruno Jean-François - 2025 - Substance 54 (1):210-217.
    Then, the gardener-fisherman looked at me, and he lifted a heavy axe. I stayed at the window and I did not move until he had finished cutting down the whip-tree. I had to, even though I felt every blow of the axe as if it were planted in my flesh. / That was the price of my freedom. I will not come back.But as for me, I am other. As for me, I have decided to say no, and in the (...)
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  35.  74
    Heritable Epigenetic Changes Alter Transgenerational Waveforms Maintained by Cycling Stores of Information.Antony M. Jose - 2020 - Bioessays 42 (7):1900254.
    Our view of heredity can potentially be distorted by the ease of introducing heritable changes in the replicating gene sequences but not in the cycling assembly of regulators around gene sequences. Here, key experiments that have informed the understanding of heredity are reinterpreted to highlight this distortion and the possible variety of heritable changes are considered. Unlike heritable genetic changes, which are always associated with mutations in gene sequence, heritable epigenetic changes can be associated with physical or chemical changes in (...)
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  36.  62
    Group Immortality and Transgenerational Meaning.Matt Dean - 2023 - The Monist 106 (2):209-223.
    Excessive boredom and the inevitability of experiencing a very bad event are two commonly cited objections to the desirability of individual immortality. It isn’t clear, however, that these objections hold weight in the context of group lives—like the lives of reading groups or labor unions. I argue that this intuition is correct: neither of the objections to an immortal individual life apply to the life of an immortal group. In the end, we may not be able to wish immortality for (...)
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  37.  63
    Traumatic chain: Korean–American immigrants’ transgenerational language and racial trauma in Native Speaker.Muhammad Sohail Ahmad, Shazmeen Nawaz, Zainab Bukhari, Mubashar Nadeem & Rana Yassir Hussain - 2022 - Frontiers in Psychology 13.
    The premise of this study is to look at the intergenerational transferal of language and racial trauma of Asian immigrants in general and Korean–American immigrants in particular to a western country, the United States of America. This study investigates trauma from a psychological standpoint, based on Chang-Rae Lee’s novel Native Speaker. In describing a marker of citizenship, the novel’s title also points to who is the native language speaker and who is a native of a country, and why one who (...)
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  38. Existential Ethics and the Philosophy of Historiography: Transgenerational Life and Memory in Literary Culture.Natan Elgabsi - 2025 - Amsterdam University Press (republished by Routlegde).
    What does it mean to bear responsibility for absent others when thinking, reading, and writing about them? The hermeneutic activities of reading and writing often involve ethical relations to absent people who are referred to and spoken about in our present lives. As the human world develops historically through orality and literacy, literary culture is one way in which connections to past and future generations can be deepened. Scrutinizing responsibility in various exhortations to historicize, this book delves into the archaeological (...)
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  39.  8
    Identity and Obligation in a Transgenerational Polity.Janna Thompson - 2009 - In Axel Gosseries & Lukas H. Meyer, Intergenerational Justice. Oxford, Royaume-Uni: Oxford University Press. pp. 25-49.
    Members of a political society typically regard themselves as participating in intergenerational relationships of obligation and entitlement. They value the inheritance they received from past generations, regard themselves as indebted to their forebears, and accept an obligation to pass on their heritage to their descendants. Liberalism, with its emphasis, on rights, contracts, and welfare of existing people, does not provide an adequate basis for intergenerational obligations. Communitarianism, by stressing communal values of the embedded self, is in a better position to (...)
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  40.  61
    Haunting Legacies: Violent Histories and Transgenerational Trauma.Gabriele Schwab - 2010 - Columbia University Press.
    From mass murder to genocide, slavery to colonial suppression, acts of atrocity have lives that extend far beyond the horrific moment. They engender trauma that echoes for generations, in the experiences of those on both sides of the act. Gabriele Schwab reads these legacies in a number of narratives, primarily through the writing of postwar Germans and the descendents of Holocaust survivors. She connects their work to earlier histories of slavery and colonialism and to more recent events, such as South (...)
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  41. Grave Injustice: Disrespect Toward the Dead, Transgenerational Publicity, and Reparations.Timothy Waligore - forthcoming - Journal of Social Philosophy.
    Journal of Social Philosophy, EarlyView.
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  42.  43
    Clarifying the public misrepresentation of transgenerational epigenetic inheritance.Tara-Lyn Camilleri - 2025 - Theoretical Medicine and Bioethics 46 (5):433-435.
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  43.  30
    Three generations, one nation: how mediated national assimilation shapes transgenerational views about “others” in foreign news.Matan Aharoni & Sabina Lissitsa - 2025 - Journal of Information, Communication and Ethics in Society 23 (4):507-525.
    Purpose This study aims to challenge the theoretical assumption of differences in the perception of European asylum seekers as “others” between Generations X, Y and Z in a cross-cultural encounter mediating foreign news. The research examines how media representation influences perceptions of geographically and culturally distant “others” among Israeli heavy news consumers. Design/methodology/approach This study used a qualitative methodology through 36 semi-structured interviews with participants across three generations. The data was analyzed using thematic analysis to identify patterns in perceptions toward (...)
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  44.  84
    The Psychosomatic Relationship As A Symbolic Circular Communication: Subjective And Transgenerational Dreams.Giuseppe Mannino, Veronica Montefiori, Manuela Vitiello, Calogero Iacolino, Monica Pellerone, Giuliana La Fiura, Antonino Bernardone, Erika Faraci & Serena Giunta - 2019 - World Futures 75 (7):426-441.
    The human being can be divided into body and mind, two inextricably linked aspects influencing each other. From birth, the body is the site of emotional experiences thanks to cellular memory. The t...
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  45. The Young Experts Symposium 2022 “Understanding Chinese Culture in the World”: Reflections on a Transgenerational and Interdisciplinary Exchange of Thoughts.David Bartosch & Bei Peng - 2024 - International Communication of Chinese Culture 11 (1):1–9.
    This first contribution to the special issue “Understanding Chinese Culture in the World” represents a philosophical proem regarding the format and general aim of the Young Experts Symposium 2022 (YES 2022), which was held online at Beijing Normal University, Zhuhai (China) and provided a platform for topics related to classical, modern, futuristic, and comparative perspectives on Chinese culture—across generations, cultures, and disciplines. Furthermore, it outlines the basic content of the six papers in this special issue that resulted from this event, (...)
     
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  46.  32
    Jewish Agents of Memory in Linda Grant’s Still Here: A Transgenerational and Intersectional Feminist Reading.Silvia Pellicer-Ortín - 2021 - The European Legacy 26 (3):228-242.
    1. Transmodernity, in the words of Irena Ateljevic, is “an umbrella term that connotes the emerging socio-cultural, economic, political and philosophical shift” which we are experiencing in the era...
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  47.  37
    Meiotic Pairing Inadequacies at the Levels of X Chromosome, Gene, or Base: Epigenetic Tagging for Transgenerational Error-Correction Guided by a Future Homologous Duplex.Virgil R. Reese & Donald R. Forsdyke - 2016 - Biological Theory 11 (3):150-157.
    In contrast to the two X chromosomes that participate equally in oogenic meiosis in mammals, during spermatogenesis the solitary X chromosome can be regarded as an inadequate pairing partner for the Y chromosome. Hence it is epigenetically silenced and consigned to the XY body. This silenced state can transfer between generations. The sleeping X will awake when in a female cell with an accompanying maternally donated X chromosome. Transgene experiments in nematodes indicate that a similar process can operate at the (...)
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  48.  87
    Haunting Legacies: Violent Histories and Transgenerational Trauma. By Gabriele Schwab.Reina Van Der Wiel - 2012 - The European Legacy 17 (6):856-857.
  49.  82
    A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line.Adelheid Soubry, Cathrine Hoyo, Randy L. Jirtle & Susan K. Murphy - 2014 - Bioessays 36 (4):359-371.
    Literature on maternal exposures and the risk of epigenetic changes or diseases in the offspring is growing. Paternal contributions are often not considered. However, some animal and epidemiologic studies on various contaminants, nutrition, and lifestyle‐related conditions suggest a paternal influence on the offspring's future health. The phenotypic outcomes may have been attributed to DNA damage or mutations, but increasing evidence shows that the inheritance of environmentally induced functional changes of the genome, and related disorders, are (also) driven by epigenetic components. (...)
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  50.  90
    Soma to germline inheritance of extrachromosomal genetic information via a LINE‐1 reverse transcriptase‐based mechanism.Corrado Spadafora - 2016 - Bioessays 38 (8):726-733.
    Mature spermatozoa are permeable to foreign DNA and RNA molecules. Here I propose a model, whereby extrachromosomal genetic information, mostly encoded in the form of RNA in somatic cells, can cross the Weismann barrier and reach epididymal spermatozoa. LINE‐1 retrotransposon‐derived reverse transcriptase (RT) can play key roles in the process by expanding the RNA‐encoded information. Retrotransposon‐encoded RT is stored in mature gametes, is highly expressed in early embryos and undifferentiated cells, and becomes downregulated in differentiated cells. In turn, RT plays (...)
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