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A perpetual source of DNA or something really different: ethical issues in the creation of cell lines for African genomics research
Jantina de Vries, Akin Abayomi, James Brandful, Katherine Littler, Ebony Madden, Patricia Marshall, Odile Ouwe Oukem-Boyer & Janet Seeley
BMC Medical Ethics 15 (1):60 (2014)
Abstract
The rise of genomic studies in Africa – not least due to projects funded under H3Africa – is associated with the development of a small number of biorepositories across Africa. For the ultimate success of these biorepositories, the creation of cell lines including those from selected H3Africa samples would be beneficial. In this paper, we map ethical challenges in the creation of cell lines.Other Versions
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Citations of this work
Predictors of consent to cell line creation and immortalisation in a South African schizophrenia genomics study.Megan M. Campbell, Jantina de Vries, Sibonile G. Mqulwana, Michael M. Mndini, Odwa A. Ntola, Deborah Jonker, Megan Malan, Adele Pretorius, Zukiswa Zingela, Stephanus Van Wyk, Dan J. Stein & Ezra Susser - 2018 - BMC Medical Ethics 19 (1):72.
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Commodification of biomaterials and data when funding is contingent to transfer in biobank research.Mantombi Maseme - 2021 - Medicine, Health Care and Philosophy 24 (4):667-675.
Legal and Ethical Challenges of International Direct-to-Participant Genomic Research: Conclusions and Recommendations.Mark A. Rothstein, Ma'N. H. Zawati, Laura M. Beskow, Kathleen M. Brelsford, Kyle B. Brothers, Catherine M. Hammack-Aviran, James W. Hazel, Yann Joly, Michael Lang, Dimitri Patrinos, Andrea Saltzman & Bartha Maria Knoppers - 2019 - Journal of Law, Medicine and Ethics 47 (4):705-731.
Developing an Evidence-base to Guide Ethical Action in Global Challenges Research in Complex and Fragile Contexts: A Scoping Review of the Literature.Clara Calia, Cristóbal Guerra, Corinne Reid, Charles Marley, Paulina Barrera, Abdul-Gafar Tobi Oshodi & Lisa Boden - 2022 - Ethics and Social Welfare 16 (1):54-72.
References found in this work
Broadening consent--and diluting ethics?B. Hofmann - 2009 - Journal of Medical Ethics 35 (2):125-129.
Challenges in biobank governance in Sub-Saharan Africa.Ciara Staunton & Keymanthri Moodley - 2013 - BMC Medical Ethics 14 (1):35.
Voluntary participation and comprehension of informed consent in a genetic epidemiological study of breast cancer in Nigeria.Patricia A. Marshall, Clement A. Adebamowo, Adebowale A. Adeyemo, Temidayo O. Ogundiran, Teri Strenski, Jie Zhou & Charles N. Rotimi - 2014 - BMC Medical Ethics 15 (1):38.
Homo Economicus Commercialization of Body Tissue in the Age of Biotechnology.Dorothy Nelkin & Lori Andrews - 1998 - Hastings Center Report 28 (5):30-39.
The Alienation of Body Tissue and the Biopolitics of Immortalized Cell Lines.Margaret Lock - 2001 - Body and Society 7 (2-3):63-91.
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