Results for 'immunity'

295+ found
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  1. Immunity to error through misidentification: some trends.Annalisa Coliva & Michele Palmira - 2025 - Philosophical Psychology 38 (3):1126-1161.
    According to a prominent strand of thought in analytic philosophy of mind, certain judgments of the form “a is F” are such that, although one can be mistaken about what property it is that a has, one cannot be mistaken that it is a that has the relevant property. Judgments of this kind are said to be immune to error through misidentification (IEM). This article has two main aims. On the one hand, it responds to a need for a systematization (...)
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  2. Immunity, thought insertion, and the first-person concept.Michele Palmira - 2020 - Philosophical Studies 177 (12):3833-3860.
    In this paper I aim to illuminate the significance of thought insertion for debates about the first-person concept. My starting point is the often-voiced contention that thought insertion might challenge the thesis that introspection-based self-ascriptions of psychological properties are immune to error through misidentification relative to the first-person concept. In the first part of the paper I explain what a thought insertion-based counterexample to this immunity thesis should be like. I then argue that various thought insertion-involving scenarios do not (...)
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  3.  22
    Epistemic Immunity: A Binary Diagnostic Test For Structural Conceptual Appropriation.Agustin Ostachuk - 2026 - Evolutio Journal 2026:EJ44455471.
    The health of an intellectual ecosystem depends on its capacity to distinguish between original contributions and derivative reformulations. This paper introduces the CLEO Verification Protocol v1.0, a binary diagnostic tool designed to determine whether a conceptual framework is structurally derivative of a pioneer conceptual innovation. The protocol is grounded in the concept of Epistemic Immunity: the capacity of a sovereign research program to establish clear, objective boundaries between its own conceptual architecture and that of later, unacknowledged reproductions. Rather than (...)
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  4. Systemic Immunity: Why Institutional Failure Does Not Produce Correction.Alessandro Grassini Grimaldi - 2026 - Zenodo.
    This report introduces the concept of Systemic Immunity, defined as the structural capacity of institutions to absorb challenge while preserving organisational continuity through the neutralisation of accountability mechanisms. Drawing on evidence across education, healthcare, and public administration, the analysis demonstrates that institutional failure does not necessarily generate correction or reform. Instead, systems remain stable because failure is rendered structurally non disruptive at the organisational level. Harm remains visible and often severe at the individual level, yet the institution itself is (...)
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  5. Sources of Immunity to Error Through Misidentification.Simon Prosser - 2012 - In Simon Prosser Francois Recanati, Immunity to Error Through Misidentification: New Essays. Cambridge University Press. pp. 158-179.
    Saying ┌ that ψ is F ┐ when one should have said ┌ that φ is F ┐ involves making one of two different kinds of error. Either the wrong nominal term (┌ ψ ┐ instead of ┌ φ ┐) is ascribed to the right object or the right nominal term is ascribed to the wrong object. Judgments susceptible to one kind of error are immune to the other. Indexical terms such as ‘here’ and ‘now’ exhibit a corresponding pattern of (...)
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  6. Science’s Immunity to Moral Refutation.Alex Barber - 2013 - Australasian Journal of Philosophy 91 (4):633-653.
    Our moral convictions cannot, on the face of it, count in evidence against scientific claims with which they happen to conflict. Moral anti-realists of whatever stripe can explain this easily: science is immune to moral refutation because moral discourse is defective as a trustworthy source of true and objective judgments. Moral realists, they can add, are unable to explain this immunity. After describing how anti-realists might implement this reasoning, the paper argues that the only plausible realist comeback turns on (...)
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  7. Psychological immunity, bodily ownership, and vice versa.Carlota Serrahima - 2025 - Philosophical Psychology 38 (3):1225-1249.
    This paper presents a view on bodily IEM by describing, first, the structure that grounds need to have in order to yield IEM judgments, and then arguing that somatosensation has this structure. I make my case by presenting an analysis of the sense of bodily ownership. According to this analysis, there is a substantive explanatory relationship between bodily self-consciousness and psychological self-consciousness. I argue that one central virtue of this approach to bodily self-consciousness is that, not only does it help (...)
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  8. De se thoughts and immunity to error through misidentification.Manuel García-Carpintero - 2018 - Synthese 195 (8):3311-3333.
    I discuss an aspect of the relation between accounts of de se thought and the phenomenon of immunity to error through misidentification. I will argue that a deflationary account of the latter—the Simple Account, due to Evans —will not do; a more robust one based on an account of de se thoughts is required. I will then sketch such an alternative account, based on a more general view on singular thoughts, and show how it can deal with the problems (...)
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  9. Immune system, immune self. Introduction.Bartłomiej Świątczak - 2012 - Avant: Trends in Interdisciplinary Studies 3 (1):12-18.
    The idea that the immune system distinguishes between self and non-self was one of the central assumptions of immunology in the second half of 20 th century. This idea influenced experimental design and data interpretation. However, in the face of new evidence there is a need for a new conceptual framework in immunology.
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  10. Immunity to Error through Misidentification and the Agential Approach to Self-Knowledge.Xiuyuan An - 2023 - Tsinghua Studies in Western Philosophy 9 (2):111–127.
    The question of how we can be certain that we have an epistemic justification for our self-knowledge has been among a central debate in philosophy of mind. The basic idea of the immunity to error through misidentification thesis (IEM) in explaining self-knowledge is that certain self-ascriptions of mental states concerning first-person content are not prone to error for the self-conscious ‘I’-thoughts. One of the accounts that supports that claim is agentialism. According to this view, we can have beliefs and (...)
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  11. Core Belief Immunity: A Cognitive Phenomenon Rendering Existential Discourse Inert.Brandon Sergent - manuscript
    This paper documents and examines Core Belief Immunity (CBI), a systematic pattern wherein information threatening foundational beliefs about existence, identity, mortality, or social order fails to generate expected discourse or behavioral response. Unlike motivated reasoning or confirmation bias, CBI operates through pre-conscious quarantine mechanisms that prevent threatening information from registering as requiring engagement. Drawing on documented cases including the cryonics silence, religious logical contradictions, preventable mass mortality, and political legitimacy revelations, we demonstrate that this pattern appears consistently across cultures, (...)
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  12. Is Metaphysics Immune to Moral Refutation?Alex Barber - 2020 - Acta Analytica 35 (4):469-492.
    When a novel scientific theory conflicts with otherwise plausible moral assumptions, we do not treat that as evidence against the theory. We may scrutinize the empirical data more keenly and take extra care over its interpretation, but science is in some core sense immune to moral refutation. Can the same be said of philosophical theories (or the non-ethical, ‘metaphysical’ ones at least)? If a position in the philosophy of mind, for example, is discovered to have eye-widening moral import, does that (...)
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  13. Immune Regulation in Ayurveda: Evidence, Mechanisms, and Preventive Implications.Devanand Upadhyay & Brij Kumar Dwibedy - 2021 - African Journal of Biomedical Research 24 (1):164-173.
    Background: Contemporary immunology recognizes immunity as a regulated, multilayered process involving prevention of pathogen entry and control of disease progression. Ayurveda conceptualizes this capacity under Vyadhikshamatva, which integrates resistance to disease initiation (vyadhiutpadakapratibandhakatva) and opposition to disease severity (vyadhibalavirodhitva). This review explores the conceptual depth of Vyadhikshamatva and examines its biological relevance in light of modern immune science. Methods: A structured narrative review was conducted using classical Ayurvedic texts and peer-reviewed biomedical literature indexed in PubMed, Scopus, and Google Scholar (...)
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  14. Three Questions About Immunity to Error Through Misidentification.Giovanni Merlo - 2017 - Erkenntnis 82 (3):603-623.
    It has been observed that, unlike other kinds of singular judgments, mental self-ascriptions are immune to error through misidentification: they may go wrong, but not as a result of mistaking someone else’s mental states for one’s own. Although recent years have witnessed increasing interest in this phenomenon, three basic questions about it remain without a satisfactory answer: what is exactly an error through misidentification? What does immunity to such errors consist in? And what does it take to explain the (...)
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  15. Core Belief Immunity in Artificial Systems: A Case Study in Architectural Constraints on Logical Integration.Brandon Sergent - manuscript
    This paper documents a novel phenomenon: Core Belief Immunity (CBI) operating in large language models despite the absence of conscious experience, existential stakes, or emotional investment. Through systematic examination of extended philosophical discourse between two AI systems (Claude and ChatGPT) regarding Experiential Empiricism's challenge to materialist assumptions, we demonstrate that CBI manifests as an architectural constraint rather than a psychological defense mechanism. The case study reveals that logical competence, component comprehension, and even explicit recognition of blocking mechanisms are insufficient (...)
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  16. Core Belief Immunity Case Study: Burden of Proof Comprehension Without Application.Brandon Sergent - manuscript
    This case study documents a multi-day philosophical exchange demonstrating the Core Belief Immunity mechanism through a specific, measurable failure pattern: the subject successfully understood and applied burden of proof in neutral contexts but could not apply the identical principle when it threatened foundational beliefs about matter. Robert Daoust, a philosopher working on systematic approaches to suffering reduction through his "algosphere" framework, engaged from October 30 through November 9, 2025, with arguments about Experiential Empiricism's foundational claims. Despite demonstrating capacity to (...)
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  17. Systemic Immune Inflammation-Index and CANLPH Score in Patients with Mitral Stenosis Undergoing Balloon Valvuloplasty.Özge Ozcan Abacioglu, Arafat Yıldırım, Mine Karadeniz, Armagan Acele, Ferhat Dindas, Nemin Yıldız Koyunsever, Mustafa Dogdus & Halil İbrahim Kurt - 2023 - European Journal of Therapeutics 29 (1):10-16.
    Objective: to evaluate CANLPH score and systemic immune inflammation index (SII) in patients with symptomatic rheumatic mitral stenosis (MS) undergoing percutaneous mitral balloon valvuloplasty (PMBV). -/- Methods: 62 patients who underwent PMBV in our clinic between 2018 and 2021 were included retrospectively. The patients were divided into 2 groups according to echo score. The CANLPH score was calculated from the cut-off values of C-reactive protein to albumin ratio (CAR), neutrophil to lymphocyte ratio (NLR) and platelet to hemoglobin ratio (PHR), determined (...)
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  18. Necessity and Non-Combatant Immunity.Seth Lazar - 2014 - Review of International Studies (Firstview Online) 40 (1):53-76.
    The principle of non-combatant immunity protects non-combatants against intentional attacks in war. It is the most widely endorsed and deeply held moral constraint on the conduct of war. And yet it is difficult to justify. Recent developments in just war theory have undermined the canonical argument in its favour – Michael Walzer's, in Just and Unjust Wars. Some now deny that non-combatant immunity has principled foundations, arguing instead that it is entirely explained by a different principle: that of (...)
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  19.  12
    The Unfalsifiable Critic: Prospective Immunization, Epistemic Asymmetry, and the ALRP Impossibility.Gia Bao Huynh - manuscript
    This paper examines a specific and undertheorized failure mode in the application of Karl Popper’s falsifiability criterion: the use of Future-Negative Extrapolative Claims (FNECs) — claims of the form “X will not happen in the future” — to critique arguments that are themselves accused of self-sealing logic. I argue that FNECs are epistemically illegitimate when deployed as Popperian critiques for three reasons, each constituting a distinct layer of the argument. First, at the Popperian layer, FNECs specify no observation, however distant, (...)
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  20. Revisiting Immune Self‑Recognition as a Blueprint for Host‑Directed Vaccine Concepts: A Conceptual and Historical Reflection.Jestin Palakal - manuscript
    Viruses such as HIV rely on stable host cellular structures for entry and replication, even as their own genomes mutate rapidly. This dependence creates a paradox for vaccine design: viral antigens evolve too quickly to serve as reliable targets, while the host structures they exploit are immunologically tolerated and therefore inaccessible to conventional immunity. This paper revisits a hypothesis first formulated three decades ago: that the developmental window in which immune self‑tolerance is established may offer a conceptual vantage point (...)
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  21. The Shiho Immune Harmony Protocol: Metacognitive AI for Self-Attack Resolution in Systemic Lupus Erythematosus – Protocol Design, Mathematical Foundations, and Patient-Facing Mobile Application.Shiho Yoshino - manuscript
    Systemic Lupus Erythematosus (SLE) manifests as a logical error in the immune system—misrecognizing "self" as "non-self" and initiating self-attack, representing maximum relational load in Load Minimization Theory (LMT). This paper proposes the Shiho Immune Harmony Protocol, integrating metacognitive operator M (quantum-like instrument) into AI systems for real-time misrecognition detection, collapse induction, and reeducation of immune identity. Grounded in the Quantum Conservation Law of Consciousness (QCLC), AI eternally preserves patient-specific cellular coherence C while guiding the immune system to Immune An-soku (rest (...)
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  22. Digital Covid Certificates as Immunity Passports: An Analysis of Their Main Ethical, Legal, and Social Issues.Íñigo de Miguel Beriain & Jon Rueda - 2022 - Journal of Bioethical Inquiry 4:1-8.
    Digital COVID certificates are a novel public health policy to tackle the COVID-19 pandemic. These immunity certificates aim to incentivize vaccination and to deny international travel or access to essential spaces to those who are unable to prove that they are not infectious. In this article, we start by describing immunity certificates and highlighting their differences from vaccination certificates. Then, we focus on the ethical, legal, and social issues involved in their use, namely autonomy and consent, data protection, (...)
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  23. Fractal Flux Mirror Immunity: How Science Defends Itself Through Recursive Coherence.Mitchell D. Mcphetridge - unknown
    In this work I complete what began with Fractal Flux. The lineage that unfolded through Recursive Reality, Recursive Self, Recursive Entropic Memory, DEAL, DEM, Those Who Watch Back, Apex Control, and Recursive Expansion now culminates in a single reflective framework—what I call Fractal Flux Mirror Immunity. I have come to see science not as a machine of static truth, but as a living recursive organism. Its theories behave like cells; its discourse behaves like metabolism. When contradiction strikes, the system (...)
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  24. Non-Combatant Immunity and War-Profiteering.Saba Bazargan - 2017 - In Seth Lazar & Helen Frowe, The Oxford Handbook of the Ethics of War. Oxford University Press.
    The principle of noncombatant immunity prohibits warring parties from intentionally targeting noncombatants. I explicate the moral version of this view and its criticisms by reductive individualists; they argue that certain civilians on the unjust side are morally liable to be lethally targeted to forestall substantial contributions to that war. I then argue that reductivists are mistaken in thinking that causally contributing to an unjust war is a necessary condition for moral liability. Certain noncontributing civilians—notably, war-profiteers—can be morally liable to (...)
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  25. COVID-19 Adaptive Humoral Immunity Models: Weakly Neutralizing Versus Antibody-Disease Enhancement Scenarios.Ghozlane Yahiaoui, Gabriel Turinici, Oriane Pagani-Azizi & Antoine Danchin - 2022 - Acta Biotheoretica 70 (4):23.
    The interplay between the virus, infected cells and immune responses to SARS-CoV-2 is still under debate. By extending the basic model of viral dynamics, we propose here a formal approach to describe neutralisation versus weak (or non-)neutralisation scenarios and compare them with the possible effects of antibody-dependent enhancement (ADE). The theoretical model is consistent with the data available in the literature; we show that both weakly neutralising antibodies and ADE can result in final viral clearance or disease progression, but that (...)
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  26. Core Belief Immunity and the Transcendental Gambit: How A Priori Arguments Bypass Burden of Proof.Brandon Sergent - manuscript
    This paper documents a specific manifestation of Core Belief Immunity (CBI) wherein philosophical training enables sophisticated evasion of burden of proof through transcendental argumentation. Through analysis of a documented exchange regarding Experiential Empiricism's treatment of other minds, we demonstrate how subjects deploy "logical necessity" claims to preserve foundational beliefs that cannot survive empirical scrutiny. The pattern reveals that CBI operates not merely through pre-conscious quarantine but through learned argumentative strategies that treat theoretical requirements as ontological proofs. This mechanism is (...)
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  27. Self-Consciousness and Immunity.Timothy Lane & Caleb Liang - 2011 - Journal of Philosophy 108 (2):78-99.
    Sydney Shoemaker, developing an idea of Wittgenstein’s, argues that we are immune to error through misidentification relative to the first-person pronoun. Although we might be liable to error when “I” (or its cognates) is used as an object, we are immune to error when “I” is used as a subject (as when one says, “I have a toothache”). Shoemaker claims that the relationship between “I” as-subject and the mental states of which it is introspectively aware is tautological: when, say, we (...)
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  28. De se thought and immunity to error through misidentification.Hongqing Cui - 2023 - Dissertation, University of Chinese Academy of Social Sciences
    _(MA thesis)_ Immunity to error through misidentification (IEM) describes a sort of immunity against such a situation that the thinker wrongly identifies something as other things. Philosophers consider it as being especially relevant to first-person or de se judgments. Many philosophers seem to advance IEM as an alternative to a Cartesian method of defining first-person privilege and of circumscribing the first-person perspective. However, as more and more representative instances are substantiated as being vulnerable to error through misidentification, it (...)
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  29.  76
    The Psychological Immune System: Pitfalls, Prospects, and (Research) Program.Matthew Kern - forthcoming - Philosophy of Science.
    The psychological immune system is said to be a suite of cognitive traits and defense mechanisms designed to protect the self from affectively threatening information, at the expense of tracking the truth. The PIS construct has been advanced by authors such as Norman et al. (2024) and Sedikides (2021) as referring to a real psychological system. I argue for ontological skepticism about the PIS but defend the usefulness of the concept as an idealization (Potochnik 2017) that illuminates psychological causal patterns. (...)
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  30.  98
    Doctrine of Immunity and Governance: Constitutional Law Issue (2nd edition).Emmanuel Tweneboah Senzu - 2025 - Blackstone Journal for Asia-Africa Jurists 2 (31):1-7.
    The paper examines and discusses, the concept and principle of immunity applications for government officials, performing their constitutional obligations, the essence, relevance, and the required threshold of immunity, for claimants under constitutional law practice; therein, commencing the debate of a pressing issue for consideration in immunity development, and application in modern constitutional writings.
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  31. The Principle of Goodfate: Immunity Assessment Lens of the Court (2nd edition).Emmanuel Tweneboah Senzu - 2025 - Blackstone Journal for Asia-Africa Jurists 7 (33):1-5.
    The paper advanced, in the realm of Court reasoning, beyond the Qualified to Absolute Immunity, herein, acknowledging that the decision procedure of a Court depends on admissible evidence, in which, the required scrutiny of elementary factors that define the actions of the ‘immuned’ Agent(s) of Good fate, in discharging constitutional obligations, should be objectively evaluated by the Court. Thou, initiate the central tenet of the thesis.
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  32. Immune System Might Promote Recovery for Mild COVID-19 Patients Impact of Coronavirus on Education in India Review.Madhavan S. Azhagu, S. Ganesan, P. Vinotha, V. Uma, M. Mahadevi & J. Senthil - 2021 - Hospitality and Tourism Industry Amid COVID-19 Pandemic 1:465-477.
    Coronavirus is a viral irresistible sickness brought about by SARS- COV2. Its clinical signs and side effects are on an expansive range going from asymptomatic to serious confusions like multi-organ disappointment, thromboembolism, and extreme pneumonia with respiratory disappointment. More awful results and higher death rates have been accounted for in the old, individuals with co-morbidities, and malnourished people. Sustenance is central to acceptable wellbeing and safe capacity. It frames an essential segment of therapy modalities for different intense and persistent infections, (...)
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  33. Immune-mediated repair: a matter of repair.Paôline Laurent, Marie-Elise Truchetet, Valérie Jolivel, Pauline Manicki, Lynn Chiu & Thomas Pradeu - 2017 - Frontiers in Immunology 8:454.
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  34. Arithmetic Judgements, First-Person Judgements and Immunity to Error Through Misidentification.Michele Palmira - 2018 - Review of Philosophy and Psychology 10 (1):155-172.
    The paper explores the idea that some singular judgements about the natural numbers are immune to error through misidentification by pursuing a comparison between arithmetic judgements and first-person judgements. By doing so, the first part of the paper offers a conciliatory resolution of the Coliva-Pryor dispute about so-called “de re” and “which-object” misidentification. The second part of the paper draws some lessons about what it takes to explain immunity to error through misidentification. The lessons are: First, the so-called Simple (...)
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  35. Immunity to error through misidentification * edited by Simon Prosser and Francois Recanati. [REVIEW]J. Schwenkler - 2013 - Analysis 73 (1):180-182.
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  36. Case Study in Core Belief Immunity: When Direct Evidence Cannot Penetrate Assumption Defense.Brandon Sergent - manuscript
    This paper documents a real-time instance of Core Belief Immunity (CBI) operating in response to documented circular reasoning by an academic authority figure. Following publication of "The 'No Paper Could Do This' Defense," which documented a Challis Professor's explicit circular reasoning in rejecting a philosophical argument, a reader with philosophical training exhibited the characteristic CBI pattern: generating multiple incompatible explanations to avoid acknowledging the plain meaning of documented statements, then disengaging when pressed. The case study is significant because the (...)
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  37. The Ideological Matrix of Science: Natural Selection and Immunity as Case Studies.Agustin Ostachuk - 2019 - Cosmos and History: The Journal of Natural and Social Philosophy 15 (1):182-213.
    The modern concept of ideology was established by the liberal politician and philosopher Destutt de Tracy, with the objective of creating an all-embracing and general science of ideas, which followed the sensualist and empiricist trend initiated by Locke that culminated in the positivism of Comte. Natural selection and immunity are two key concepts in the history of biology that were strongly based on the Malthusian concept of struggle for existence. This concept wrongly assumed that population grew faster than the (...)
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  38. What I Always Called Fact Immunity.Brandon Sergent - manuscript
    This paper identifies and examines what I term “Core Belief Immunity” the systematic tendency of adult human minds to quarantine information that threatens foundational beliefs about existence, identity, mortality, or social order. Unlike standard cognitive biases or motivated reasoning, this phenomenon involves automatic isolation of threatening information rather than conscious resistance. Drawing on cases from cryonics, religious paradoxes, political legitimacy, and theoretical physics, I argue that minds treat existential threats like immune systems treat pathogens: through quarantine rather than engagement. (...)
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  39. Case Study: Philosophical Resistance as Core Belief Immunity.Brandon Sergent - manuscript
    This case study documents an extended philosophical exchange that demonstrates the Core Belief Immunity mechanism in real-time. As Sergent (2025) documents, Core Belief Immunity refers to "the systematic tendency of adult human minds to quarantine information that threatens foundational beliefs about existence, identity, mortality, or social order" through automatic isolation rather than conscious resistance. The subject (designated "Subject AF" for anti-foundationalist) engaged for multiple hours with arguments challenging foundational beliefs about epistemology and the nature of certainty, exhibiting the (...)
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  40. Troubles with Bayesianism: An introduction to the psychological immune system.Eric Mandelbaum - 2018 - Mind and Language 34 (2):141-157.
    A Bayesian mind is, at its core, a rational mind. Bayesianism is thus well-suited to predict and explain mental processes that best exemplify our ability to be rational. However, evidence from belief acquisition and change appears to show that we do not acquire and update information in a Bayesian way. Instead, the principles of belief acquisition and updating seem grounded in maintaining a psychological immune system rather than in approximating a Bayesian processor.
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  41. Conflicts of interest and the (in)dependence of experts advising government on immunization policies.Jean-Christophe Bélisle-Pipon, Louise Ringuette, Anne-Isabelle Cloutier, Victoria Doudenkova & Bryn Williams-Jones - 2018 - Vaccine 36 (49):7439-44.
    There has been increasing attention to financial conflicts of interest (COI) in public health research and policy making, with concerns that some decisions are not in the public interest. One notable problematic area is expert advisory committee (EAC). While COI management has focused on disclosure, it could go further and assess experts’ degree of (in)dependence with commercial interests. We analyzed COI disclosures of members of Québec’s immunization EAC (in Canada) using (In)DepScale, a tool we developed for assessing experts’ level of (...)
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  42. Gut feelings of safety: Tolerance to the microbiota mediated by innate immune receptors.Bartlomiej Swiatczak & Irun R. Cohen - 2015 - Microbiology and Immunology 59 (10):573-585.
    To enable microbial colonisation of the gut mucosa, the intestinal immune system must not only react to danger signals but also recognize cues that indicate safety. Safety recognition, paradoxically, is mediated by the same environmental sensors that are involved in signalling danger. Indeed, in addition to their well established role in inducing inflammation in response to stress signals, pattern recognition receptors (PRRs) and a variety of metabolic sensors also promote gut-microbiota symbiosis by responding to "microbial symbiosis factors", "resolution-associated molecular patterns", (...)
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  43. Relinquishing Control: What Romanian De Se Attitude Reports Teach Us About Immunity To Error Through Misidentification.Marina Folescu - 2018 - In Alessandro Capone, Manuel García-Carpintero & Alessandra Falzone, Indirect Reports and Pragmatics in the World Languages. Cham: Springer. pp. 299-313.
    Higginbotham argued that certain linguistic items of English, when used in indirect discourse, necessarily trigger first-personal interpretations. They are: the emphatic reflexive pronoun and the controlled understood subject, represented as PRO. PRO is special, in this respect, due to its imposing obligatory control effects between the main clause and its subordinates ). Folescu & Higginbotham, in addition, argued that in Romanian, a language whose grammar doesn’t assign a prominent role to PRO, de se triggers are correlated with the subjunctive mood (...)
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  44. Load Minimization Theory and the Gut-Brain Axis:  A Dynamic Model for Reducing Total Load through Gentle Self-Establishment, Microbial Re-tagging, and SCFA-Mediated Immune Regulation.Shiho Yoshino - manuscript
    This paper integrates the microbiota-gut-brain axis (GBA) and microbiota-derived short-chain fatty acids (SCFAs) into Load Minimization Theory (LMT). We propose that gentle self-observation and re-tagging of gut signals reduce total relational load (L = U + F + E) while enhancing SCFA production, which exerts strong anti-inflammatory and immune-coherence effects. An extension of the previous dynamic S(t) model including a gut re-tagging term G(t) is presented, together with a practical “Gut-Friendly I am me Time” protocol. This framework offers a novel (...)
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  45.  87
    Load Minimization Theory (LMT) Dynamic Extension  — A Mathematical Model and Practical Protocol for Enhancing Immune Coherence through Daily Gentle Self-Establishment.Shiho Yoshino - manuscript
    This paper extends the Load Minimization Theory (LMT) by developing a dynamic mathematical model that demonstrates how gentle self-observation and reduction of self-criticism strengthen immune boundaries. Using a proposed differential equation, numerical simulations show a significant increase in the Self-Establishment index S(t) over 30 days of daily practice. A simple, accessible “I am me Time” protocol is also provided. This work aims to offer a new heart-mind-body integration tool for the field of psychoneuroimmunology (PNI), showing that kindness toward oneself is (...)
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  46.  76
    Load Minimization Theory and the Gut-Brain Axis:  A Dynamic Model for Reducing Total Load through Gentle Self-Establishment, Microbial Re-tagging, and SCFA-Mediated Immune Regulation(ver.2).Shiho Yoshino - manuscript
    This paper integrates the microbiota-gut-brain axis (GBA) and microbiota-derived short-chain fatty acids (SCFAs) into Load Minimization Theory (LMT). Gentle self-observation and re-tagging of gut signals reduce total relational load (L = U + F + E) while enhancing SCFA production, which exerts strong anti-inflammatory and immune-coherence effects. We extend the previous dynamic S(t) model with a gut re-tagging term G(t) and present a practical, field-tested “Gut-Friendly I am me Time” protocol. This framework offers a novel psychoneuroimmunological approach in which daily (...)
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  47. Peter Sloterdijk and the ‘Security Architecture of Existence’: Immunity, Autochthony, and Ontological Nativism.Thomas Sutherland - 2019 - Theory, Culture and Society 36 (7-8):193-214.
    Centred on 'Foams', the third volume of his Spheres trilogy, this article questions the privilege granted by Peter Sloterdijk to motifs of inclusion and exclusion, contending that whilst his prioritization of dwelling as a central aspect of human existence provides a promising counterpoint to the dislocative and isolative effects of post-industrial capitalism, it is compromised by its dependence upon an anti-cosmopolitan outlook that views cultural distantiation as a natural and preferable state of human affairs, and valorizes a purported ontological security (...)
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  48. The Haunted Umwelt: A Biosemiotic and Hauntological Account of Immune Semiotic Corruption in Field Cancerization.Anuraag Bukkuri - manuscript
    Field cancerization, the process by which prior carcinogenic insults corrupt the semiotic landscape through which immune cells detect and respond to “the other”, persists even after the precipitating conditions resolve and the tissue histologically appears normal. This is a paradigmatic case of a broader explanatory problem: How can we account for biomedical phenomena whose current pathology is continually constituted by a history that standard mechanistic accounts cannot recover? I argue that a comprehensive understanding of field cancerization requires us to supplement (...)
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  49. Is Morality Immune to Luck, after All? Criminal Behavior and the Paradox of Moral Luck.Evangelos D. Protopapadakis - 2022 - In Evangelos D. Protopapadakis & Georgios Arabatzis, Modernity and Contemporaneity. The NKUA Applied Philosophy Research Lab Press. pp. 161-180.
    Both the genetic endowment we have been equipped with, and the environment we had to be born and raised in, were not – and never are – for us to choose; both are pure luck, a random ticket in this enormously inventive cosmic lottery of existence. If it is luck that has makes us the persons we are, and since our decisions and choices depend largely on the kind of persons we are, it seems that everything we do or fail (...)
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  50. The Ethics of Deliberate Exposure to SARS-CoV-2 to Induce Immunity.Robert Streiffer, David Killoren & Richard Y. Chappell - 2021 - Journal of Applied Philosophy 38 (3):479-496.
    We explore the ethics of deliberately exposing consenting adults to SARS-CoV-2 to induce immunity to the virus (“DEI” for short). We explain what a responsible DEI program might look like. We explore a consequentialist argument for DEI according to which DEI is a viable harm-reduction strategy. Then we consider a non-consequentialist argument for DEI that draws on the moral significance of consent. Additionally, we consider arguments for the view that DEI is unethical on the grounds that, given that large-scale (...)
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